These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

132 related articles for article (PubMed ID: 12182861)

  • 1. Quaternary salts of E2020 analogues as acetylcholinesterase inhibitors for the reversal of neuromuscular block.
    Clark JK; Cowley P; Muir AW; Palin R; Pow E; Prosser AB; Taylor R; Zhang MQ
    Bioorg Med Chem Lett; 2002 Sep; 12(18):2565-8. PubMed ID: 12182861
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Novel piperidinium and pyridinium agents as water-soluble acetylcholinesterase inhibitors for the reversal of neuromuscular blockade.
    Palin R; Clark JK; Cowley P; Muir AW; Pow E; Prosser AB; Taylor R; Zhang MQ
    Bioorg Med Chem Lett; 2002 Sep; 12(18):2569-72. PubMed ID: 12182862
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis and acetylcholinesterase inhibitory activity of huperzine A-E2020 combined compound.
    Zeng F; Jiang H; Zhai Y; Zhang H; Chen K; Ji R
    Bioorg Med Chem Lett; 1999 Dec; 9(23):3279-84. PubMed ID: 10612585
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Kinetic study on the inhibition of acetylcholinesterase by 1-benzyl-4-[(5,6-dimethoxy-1-indanon)-2-yl]methylpiperidine hydrochloride (E2020).
    Nochi S; Asakawa N; Sato T
    Biol Pharm Bull; 1995 Aug; 18(8):1145-7. PubMed ID: 8535413
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structure of acetylcholinesterase complexed with E2020 (Aricept): implications for the design of new anti-Alzheimer drugs.
    Kryger G; Silman I; Sussman JL
    Structure; 1999 Mar; 7(3):297-307. PubMed ID: 10368299
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis and evaluation of tacrine-E2020 hybrids as acetylcholinesterase inhibitors for the treatment of Alzheimer's disease.
    Shao D; Zou C; Luo C; Tang X; Li Y
    Bioorg Med Chem Lett; 2004 Sep; 14(18):4639-42. PubMed ID: 15324879
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Donepezil-Based Central Acetylcholinesterase Inhibitors by Means of a "Bio-Oxidizable" Prodrug Strategy: Design, Synthesis, and in Vitro Biological Evaluation.
    Peauger L; Azzouz R; Gembus V; Ţînţaş ML; Sopková-de Oliveira Santos J; Bohn P; Papamicaël C; Levacher V
    J Med Chem; 2017 Jul; 60(13):5909-5926. PubMed ID: 28613859
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Design, synthesis and biological activity of novel donepezil derivatives bearing N-benzyl pyridinium moiety as potent and dual binding site acetylcholinesterase inhibitors.
    Lan JS; Zhang T; Liu Y; Yang J; Xie SS; Liu J; Miao ZY; Ding Y
    Eur J Med Chem; 2017 Jun; 133():184-196. PubMed ID: 28388521
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Targeting Alzheimer's disease by investigating previously unexplored chemical space surrounding the cholinesterase inhibitor donepezil.
    van Greunen DG; Cordier W; Nell M; van der Westhuyzen C; Steenkamp V; Panayides JL; Riley DL
    Eur J Med Chem; 2017 Feb; 127():671-690. PubMed ID: 27823887
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Design, synthesis and evaluation of novel heterodimers of donepezil and huperzine fragments as acetylcholinesterase inhibitors.
    Hu Y; Zhang J; Chandrashankra O; Ip FC; Ip NY
    Bioorg Med Chem; 2013 Feb; 21(3):676-83. PubMed ID: 23273608
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The rationale for E2020 as a potent acetylcholinesterase inhibitor.
    Kawakami Y; Inoue A; Kawai T; Wakita M; Sugimoto H; Hopfinger AJ
    Bioorg Med Chem; 1996 Sep; 4(9):1429-46. PubMed ID: 8894101
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Dynamic mechanism of E2020 binding to acetylcholinesterase: a steered molecular dynamics simulation.
    Niu C; Xu Y; Xu Y; Luo X; Duan W; Silman I; Sussman JL; Zhu W; Chen K; Shen J; Jiang H
    J Phys Chem B; 2005 Dec; 109(49):23730-8. PubMed ID: 16375354
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Acetylcholinesterase protection and the anti-diisopropylfluorophosphate efficacy of E2020.
    Galli A; Mori F; Benini L; Cacciarelli N
    Eur J Pharmacol; 1994 Apr; 270(2-3):189-93. PubMed ID: 8039548
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis and biological activity of new donepezil-hydrazinonicotinamide hybrids.
    Zurek E; Szymański P; Mikiciuk-Olasik E
    Drug Res (Stuttg); 2013 Mar; 63(3):137-44. PubMed ID: 23447117
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Neostigmine reversal of vecuronium neuromuscular block and the influence of renal failure.
    Dhonneur G; Rebaine C; Slavov V; Ruggier R; De Chaubry V; Duvaldestin P
    Anesth Analg; 1996 Jan; 82(1):134-8. PubMed ID: 8712389
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Donepezil hydrochloride: a treatment drug for Alzheimer's disease.
    Sugimoto H
    Chem Rec; 2001; 1(1):63-73. PubMed ID: 11893059
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis and structure-activity relationships of acetylcholinesterase inhibitors: 1-benzyl-4-[(5,6-dimethoxy-1-oxoindan-2-yl)methyl]piperidine hydrochloride and related compounds.
    Sugimoto H; Iimura Y; Yamanishi Y; Yamatsu K
    J Med Chem; 1995 Nov; 38(24):4821-9. PubMed ID: 7490731
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Three-dimensional structure of a complex of E2020 with acetylcholinesterase from Torpedo californica.
    Kryger G; Silman I; Sussman JL
    J Physiol Paris; 1998; 92(3-4):191-4. PubMed ID: 9789806
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Kinetic and structural studies on the interactions of Torpedo californica acetylcholinesterase with two donepezil-like rigid analogues.
    Caliandro R; Pesaresi A; Cariati L; Procopio A; Oliverio M; Lamba D
    J Enzyme Inhib Med Chem; 2018 Dec; 33(1):794-803. PubMed ID: 29651884
    [TBL] [Abstract][Full Text] [Related]  

  • 20. [Advances in search for acetylcholinesterase inhibitor based on the double active sites hypothesis].
    Jin GY; Xia Y; Bai DL
    Yao Xue Xue Bao; 2002 Sep; 37(9):749-52. PubMed ID: 12567905
    [No Abstract]   [Full Text] [Related]  

    [Next]    [New Search]
    of 7.