BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

203 related articles for article (PubMed ID: 12183412)

  • 1. Phosphorylation of serine 1387 in Brca1 is specifically required for the Atm-mediated S-phase checkpoint after ionizing irradiation.
    Xu B; O'Donnell AH; Kim ST; Kastan MB
    Cancer Res; 2002 Aug; 62(16):4588-91. PubMed ID: 12183412
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Involvement of Brca1 in S-phase and G(2)-phase checkpoints after ionizing irradiation.
    Xu B; Kim St ; Kastan MB
    Mol Cell Biol; 2001 May; 21(10):3445-50. PubMed ID: 11313470
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Differing effects of breast cancer 1, early onset (BRCA1) and ataxia-telangiectasia mutated (ATM) mutations on cellular responses to ionizing radiation.
    Mamon HJ; Dahlberg W; Azzam EI; Nagasawa H; Muto MG; Little JB
    Int J Radiat Biol; 2003 Oct; 79(10):817-29. PubMed ID: 14630541
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Role for ATM in DNA damage-induced phosphorylation of BRCA1.
    Gatei M; Scott SP; Filippovitch I; Soronika N; Lavin MF; Weber B; Khanna KK
    Cancer Res; 2000 Jun; 60(12):3299-304. PubMed ID: 10866324
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Two molecularly distinct G(2)/M checkpoints are induced by ionizing irradiation.
    Xu B; Kim ST; Lim DS; Kastan MB
    Mol Cell Biol; 2002 Feb; 22(4):1049-59. PubMed ID: 11809797
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Both DNA topoisomerase II-binding protein 1 and BRCA1 regulate the G2-M cell cycle checkpoint.
    Yamane K; Chen J; Kinsella TJ
    Cancer Res; 2003 Jun; 63(12):3049-53. PubMed ID: 12810625
    [TBL] [Abstract][Full Text] [Related]  

  • 7. BRCA1-BARD1 complexes are required for p53Ser-15 phosphorylation and a G1/S arrest following ionizing radiation-induced DNA damage.
    Fabbro M; Savage K; Hobson K; Deans AJ; Powell SN; McArthur GA; Khanna KK
    J Biol Chem; 2004 Jul; 279(30):31251-8. PubMed ID: 15159397
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Functional link of BRCA1 and ataxia telangiectasia gene product in DNA damage response.
    Li S; Ting NS; Zheng L; Chen PL; Ziv Y; Shiloh Y; Lee EY; Lee WH
    Nature; 2000 Jul; 406(6792):210-5. PubMed ID: 10910365
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Involvement of the cohesin protein, Smc1, in Atm-dependent and independent responses to DNA damage.
    Kim ST; Xu B; Kastan MB
    Genes Dev; 2002 Mar; 16(5):560-70. PubMed ID: 11877376
    [TBL] [Abstract][Full Text] [Related]  

  • 10. BRCA1-mediated G2/M cell cycle arrest requires ERK1/2 kinase activation.
    Yan Y; Spieker RS; Kim M; Stoeger SM; Cowan KH
    Oncogene; 2005 May; 24(20):3285-96. PubMed ID: 15735702
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Requirement of ATM-dependent phosphorylation of brca1 in the DNA damage response to double-strand breaks.
    Cortez D; Wang Y; Qin J; Elledge SJ
    Science; 1999 Nov; 286(5442):1162-6. PubMed ID: 10550055
    [TBL] [Abstract][Full Text] [Related]  

  • 12. ATM-dependent hyper-radiosensitivity in mammalian cells irradiated by heavy ions.
    Xue L; Yu D; Furusawa Y; Cao J; Okayasu R; Fan S
    Int J Radiat Oncol Biol Phys; 2009 Sep; 75(1):235-43. PubMed ID: 19695441
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis.
    Falck J; Mailand N; SyljuÄsen RG; Bartek J; Lukas J
    Nature; 2001 Apr; 410(6830):842-7. PubMed ID: 11298456
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The mismatch repair system is required for S-phase checkpoint activation.
    Brown KD; Rathi A; Kamath R; Beardsley DI; Zhan Q; Mannino JL; Baskaran R
    Nat Genet; 2003 Jan; 33(1):80-4. PubMed ID: 12447371
    [TBL] [Abstract][Full Text] [Related]  

  • 15. ATM activation by ionizing radiation requires BRCA1-associated BAAT1.
    Aglipay JA; Martin SA; Tawara H; Lee SW; Ouchi T
    J Biol Chem; 2006 Apr; 281(14):9710-8. PubMed ID: 16452482
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Dynamic changes of BRCA1 subnuclear location and phosphorylation state are initiated by DNA damage.
    Scully R; Chen J; Ochs RL; Keegan K; Hoekstra M; Feunteun J; Livingston DM
    Cell; 1997 Aug; 90(3):425-35. PubMed ID: 9267023
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cdk1 participates in BRCA1-dependent S phase checkpoint control in response to DNA damage.
    Johnson N; Cai D; Kennedy RD; Pathania S; Arora M; Li YC; D'Andrea AD; Parvin JD; Shapiro GI
    Mol Cell; 2009 Aug; 35(3):327-39. PubMed ID: 19683496
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Nbs1 promotes ATM dependent phosphorylation events including those required for G1/S arrest.
    Girard PM; Riballo E; Begg AC; Waugh A; Jeggo PA
    Oncogene; 2002 Jun; 21(27):4191-9. PubMed ID: 12082606
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A subset of ATM- and ATR-dependent phosphorylation events requires the BRCA1 protein.
    Foray N; Marot D; Gabriel A; Randrianarison V; Carr AM; Perricaudet M; Ashworth A; Jeggo P
    EMBO J; 2003 Jun; 22(11):2860-71. PubMed ID: 12773400
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Genistein induces G2/M cell cycle arrest and apoptosis of human ovarian cancer cells via activation of DNA damage checkpoint pathways.
    Ouyang G; Yao L; Ruan K; Song G; Mao Y; Bao S
    Cell Biol Int; 2009 Dec; 33(12):1237-44. PubMed ID: 19732843
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.