BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

149 related articles for article (PubMed ID: 12183451)

  • 1. Alkyl-lysophospholipid accumulates in lipid rafts and induces apoptosis via raft-dependent endocytosis and inhibition of phosphatidylcholine synthesis.
    van der Luit AH; Budde M; Ruurs P; Verheij M; van Blitterswijk WJ
    J Biol Chem; 2002 Oct; 277(42):39541-7. PubMed ID: 12183451
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Different modes of internalization of apoptotic alkyl-lysophospholipid and cell-rescuing lysophosphatidylcholine.
    Van Der Luit AH; Budde M; Verheij M; Van Blitterswijk WJ
    Biochem J; 2003 Sep; 374(Pt 3):747-53. PubMed ID: 12837133
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Resistance to alkyl-lysophospholipid-induced apoptosis due to downregulated sphingomyelin synthase 1 expression with consequent sphingomyelin- and cholesterol-deficiency in lipid rafts.
    Van der Luit AH; Budde M; Zerp S; Caan W; Klarenbeek JB; Verheij M; Van Blitterswijk WJ
    Biochem J; 2007 Jan; 401(2):541-9. PubMed ID: 17049047
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A new class of anticancer alkylphospholipids uses lipid rafts as membrane gateways to induce apoptosis in lymphoma cells.
    van der Luit AH; Vink SR; Klarenbeek JB; Perrissoud D; Solary E; Verheij M; van Blitterswijk WJ
    Mol Cancer Ther; 2007 Aug; 6(8):2337-45. PubMed ID: 17699729
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Fas/CD95 down-regulation in lymphoma cells through acquired alkyllysophospholipid resistance: partial role of associated sphingomyelin deficiency.
    van Blitterswijk WJ; Klarenbeek JB; van der Luit AH; Alderliesten MC; van Lummel M; Verheij M
    Biochem J; 2009 Dec; 425(1):225-34. PubMed ID: 19824885
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Lysophosphatidylcholine and 1-O-octadecyl-2-O-methyl-rac-glycero-3-phosphocholine inhibit the CDP-choline pathway of phosphatidylcholine synthesis at the CTP:phosphocholine cytidylyltransferase step.
    Boggs KP; Rock CO; Jackowski S
    J Biol Chem; 1995 Mar; 270(13):7757-64. PubMed ID: 7706325
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The antiproliferative effect of hexadecylphosphocholine toward HL60 cells is prevented by exogenous lysophosphatidylcholine.
    Boggs K; Rock CO; Jackowski S
    Biochim Biophys Acta; 1998 Jan; 1389(1):1-12. PubMed ID: 9443598
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Lipid rafts and metabolic energy differentially determine uptake of anti-cancer alkylphospholipids in lymphoma versus carcinoma cells.
    Vink SR; van der Luit AH; Klarenbeek JB; Verheij M; van Blitterswijk WJ
    Biochem Pharmacol; 2007 Nov; 74(10):1456-65. PubMed ID: 17803969
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Apoptosis triggered by 1-O-octadecyl-2-O-methyl-rac-glycero-3-phosphocholine is prevented by increased expression of CTP:phosphocholine cytidylyltransferase.
    Baburina I; Jackowski S
    J Biol Chem; 1998 Jan; 273(4):2169-73. PubMed ID: 9442058
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Regulation of the high-affinity choline transporter activity and trafficking by its association with cholesterol-rich lipid rafts.
    Cuddy LK; Winick-Ng W; Rylett RJ
    J Neurochem; 2014 Mar; 128(5):725-40. PubMed ID: 24127780
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Effect of alkyl-lysophospholipids on phosphatidylcholine biosynthesis in leukemic cell lines.
    Vogler WR; Whigham E; Bennett WD; Olson AC
    Exp Hematol; 1985 Aug; 13(7):629-33. PubMed ID: 3861326
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Endocytosis of resveratrol via lipid rafts and activation of downstream signaling pathways in cancer cells.
    Colin D; Limagne E; Jeanningros S; Jacquel A; Lizard G; Athias A; Gambert P; Hichami A; Latruffe N; Solary E; Delmas D
    Cancer Prev Res (Phila); 2011 Jul; 4(7):1095-106. PubMed ID: 21467134
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Phosphoinositide phosphatase SHIP-1 regulates apoptosis induced by edelfosine, Fas ligation and DNA damage in mouse lymphoma cells.
    Alderliesten MC; Klarenbeek JB; van der Luit AH; van Lummel M; Jones DR; Zerp S; Divecha N; Verheij M; van Blitterswijk WJ
    Biochem J; 2011 Nov; 440(1):127-35. PubMed ID: 21793801
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The ratio of phosphatidylcholine to phosphatidylethanolamine does not predict integrity of growing MT58 Chinese hamster ovary cells.
    Niebergall LJ; Vance DE
    Biochim Biophys Acta; 2012 Feb; 1821(2):324-34. PubMed ID: 22079326
    [TBL] [Abstract][Full Text] [Related]  

  • 15. In vitro and In vivo selective antitumor activity of Edelfosine against mantle cell lymphoma and chronic lymphocytic leukemia involving lipid rafts.
    Mollinedo F; de la Iglesia-Vicente J; Gajate C; Estella-Hermoso de Mendoza A; Villa-Pulgarin JA; de Frias M; Roué G; Gil J; Colomer D; Campanero MA; Blanco-Prieto MJ
    Clin Cancer Res; 2010 Apr; 16(7):2046-54. PubMed ID: 20233887
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The alpha1a-adrenergic receptor occupies membrane rafts with its G protein effectors but internalizes via clathrin-coated pits.
    Morris DP; Lei B; Wu YX; Michelotti GA; Schwinn DA
    J Biol Chem; 2008 Feb; 283(5):2973-85. PubMed ID: 18048357
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Inhibition of phosphatidylcholine synthesis induces expression of the endoplasmic reticulum stress and apoptosis-related protein CCAAT/enhancer-binding protein-homologous protein (CHOP/GADD153).
    van der Sanden MH; Houweling M; van Golde LM; Vaandrager AB
    Biochem J; 2003 Feb; 369(Pt 3):643-50. PubMed ID: 12370080
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Lipid raft disruption prevents apoptosis induced by 2-chloro-2'-deoxyadenosine (Cladribine) in leukemia cell lines.
    Takahashi E; Inanami O; Ohta T; Matsuda A; Kuwabara M
    Leuk Res; 2006 Dec; 30(12):1555-61. PubMed ID: 16730061
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Contribution of lipid second messengers to the regulation of phosphatidylcholine synthesis during cell cycle re-entry.
    Ng MN; Kitos TE; Cornell RB
    Biochim Biophys Acta; 2004 Nov; 1686(1-2):85-99. PubMed ID: 15522825
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Disruption of lipid rafts enhances activity of botulinum neurotoxin serotype A.
    Petro KA; Dyer MA; Yowler BC; Schengrund CL
    Toxicon; 2006 Dec; 48(8):1035-45. PubMed ID: 17046039
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.