BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

363 related articles for article (PubMed ID: 12183468)

  • 1. Costimulation of Gi- and G12/G13-mediated signaling pathways induces integrin alpha IIbbeta 3 activation in platelets.
    Nieswandt B; Schulte V; Zywietz A; Gratacap MP; Offermanns S
    J Biol Chem; 2002 Oct; 277(42):39493-8. PubMed ID: 12183468
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Coordinated signaling through both G12/13 and G(i) pathways is sufficient to activate GPIIb/IIIa in human platelets.
    Dorsam RT; Kim S; Jin J; Kunapuli SP
    J Biol Chem; 2002 Dec; 277(49):47588-95. PubMed ID: 12297512
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Thrombopoietin complements G(i)- but not G(q)-dependent pathways for integrin {alpha}(IIb){beta}(3) activation and platelet aggregation.
    Campus F; Lova P; Bertoni A; Sinigaglia F; Balduini C; Torti M
    J Biol Chem; 2005 Jul; 280(26):24386-95. PubMed ID: 15863506
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Activation of G12/G13 results in shape change and Rho/Rho-kinase-mediated myosin light chain phosphorylation in mouse platelets.
    Klages B; Brandt U; Simon MI; Schultz G; Offermanns S
    J Cell Biol; 1999 Feb; 144(4):745-54. PubMed ID: 10037795
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Distinct role of Pyk2 in mediating thromboxane generation downstream of both G12/13 and integrin αIIbβ3 in platelets.
    Kim S; Cipolla L; Guidetti G; Okigaki M; Jin J; Torti M; Kunapuli SP
    J Biol Chem; 2013 Jun; 288(25):18194-203. PubMed ID: 23640884
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Unresponsiveness of platelets lacking both Galpha(q) and Galpha(13). Implications for collagen-induced platelet activation.
    Moers A; Wettschureck N; Grüner S; Nieswandt B; Offermanns S
    J Biol Chem; 2004 Oct; 279(44):45354-9. PubMed ID: 15326177
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Costimulation of the Gi-coupled ADP receptor and the Gq-coupled TXA2 receptor is required for ERK2 activation in collagen-induced platelet aggregation.
    Roger S; Pawlowski M; Habib A; Jandrot-Perrus M; Rosa JP; Bryckaert M
    FEBS Lett; 2004 Jan; 556(1-3):227-35. PubMed ID: 14706855
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Protein kinase C- and calcium-regulated pathways independently synergize with Gi pathways in agonist-induced fibrinogen receptor activation.
    Quinton TM; Kim S; Dangelmaier C; Dorsam RT; Jin J; Daniel JL; Kunapuli SP
    Biochem J; 2002 Dec; 368(Pt 2):535-43. PubMed ID: 12215172
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Critical role of ADP interaction with P2Y12 receptor in the maintenance of alpha(IIb)beta3 activation: association with Rap1B activation.
    Kamae T; Shiraga M; Kashiwagi H; Kato H; Tadokoro S; Kurata Y; Tomiyama Y; Kanakura Y
    J Thromb Haemost; 2006 Jun; 4(6):1379-87. PubMed ID: 16706985
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The roles of alpha IIb beta 3-mediated outside-in signal transduction, thromboxane A2, and adenosine diphosphate in collagen-induced platelet aggregation.
    Cho MJ; Liu J; Pestina TI; Steward SA; Thomas DW; Coffman TM; Wang D; Jackson CW; Gartner TK
    Blood; 2003 Apr; 101(7):2646-51. PubMed ID: 12446460
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Protease-activated receptors 1 and 4 do not stimulate G(i) signaling pathways in the absence of secreted ADP and cause human platelet aggregation independently of G(i) signaling.
    Kim S; Foster C; Lecchi A; Quinton TM; Prosser DM; Jin J; Cattaneo M; Kunapuli SP
    Blood; 2002 May; 99(10):3629-36. PubMed ID: 11986217
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Adenosine diphosphate (ADP)-induced thromboxane A(2) generation in human platelets requires coordinated signaling through integrin alpha(IIb)beta(3) and ADP receptors.
    Jin J; Quinton TM; Zhang J; Rittenhouse SE; Kunapuli SP
    Blood; 2002 Jan; 99(1):193-8. PubMed ID: 11756171
    [TBL] [Abstract][Full Text] [Related]  

  • 13. G(12/13) signaling pathways substitute for integrin αIIbβ3-signaling for thromboxane generation in platelets.
    Bhavaraju K; Lakhani PR; Dorsam RT; Jin J; Hitchcock IS; Sanjay A; Kunapuli SP
    PLoS One; 2011 Feb; 6(2):e16586. PubMed ID: 21347357
    [TBL] [Abstract][Full Text] [Related]  

  • 14. ADP secretion and subsequent P2Y12 receptor signalling play a crucial role in thrombin-induced ERK2 activation in human platelets.
    Fälker K; Lange D; Presek P
    Thromb Haemost; 2004 Jul; 92(1):114-23. PubMed ID: 15213852
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Different G protein-coupled signaling pathways are involved in alpha granule release from human platelets.
    Quinton TM; Murugappan S; Kim S; Jin J; Kunapuli SP
    J Thromb Haemost; 2004 Jun; 2(6):978-84. PubMed ID: 15140134
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Difference of (Ca2+)i movements in platelets stimulated by thrombin and TRAP: the involvement of alpha(IIb)beta3-mediated TXA2 synthesis.
    Aoki T; Tomiyama Y; Honda S; Senzaki K; Tanaka A; Okubo M; Takahashi F; Takasugi H; Seki J
    Thromb Haemost; 1998 Jun; 79(6):1184-90. PubMed ID: 9657446
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Galpha12 and galpha13 are phosphorylated during platelet activation.
    Offermanns S; Hu YH; Simon MI
    J Biol Chem; 1996 Oct; 271(42):26044-8. PubMed ID: 8824244
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A Gi-dependent pathway is required for activation of the small GTPase Rap1B in human platelets.
    Lova P; Paganini S; Sinigaglia F; Balduini C; Torti M
    J Biol Chem; 2002 Apr; 277(14):12009-15. PubMed ID: 11815620
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The Gi-coupled P2Y12 receptor regulates diacylglycerol-mediated signaling in human platelets.
    Guidetti GF; Lova P; Bernardi B; Campus F; Baldanzi G; Graziani A; Balduini C; Torti M
    J Biol Chem; 2008 Oct; 283(43):28795-805. PubMed ID: 18755689
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Identification of Galpha13 as one of the G-proteins that couple to human platelet thromboxane A2 receptors.
    Djellas Y; Manganello JM; Antonakis K; Le Breton GC
    J Biol Chem; 1999 May; 274(20):14325-30. PubMed ID: 10318854
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.