155 related articles for article (PubMed ID: 12185072)
1. Phosphorylation and mutations of Ser(16) in human phenylalanine hydroxylase. Kinetic and structural effects.
Miranda FF; Teigen K; Thórólfsson M; Svebak RM; Knappskog PM; Flatmark T; Martínez A
J Biol Chem; 2002 Oct; 277(43):40937-43. PubMed ID: 12185072
[TBL] [Abstract][Full Text] [Related]
2. Further studies of the role of Ser-16 in the regulation of the activity of phenylalanine hydroxylase.
Kowlessur D; Yang XJ; Kaufman S
Proc Natl Acad Sci U S A; 1995 May; 92(11):4743-7. PubMed ID: 7761394
[TBL] [Abstract][Full Text] [Related]
3. Activation of phenylalanine hydroxylase: effect of substitutions at Arg68 and Cys237.
Thórólfsson M; Teigen K; Martínez A
Biochemistry; 2003 Apr; 42(12):3419-28. PubMed ID: 12653545
[TBL] [Abstract][Full Text] [Related]
4. Structural and stability effects of phosphorylation: Localized structural changes in phenylalanine hydroxylase.
Miranda FF; Thórólfsson M; Teigen K; Sanchez-Ruiz JM; Martínez A
Protein Sci; 2004 May; 13(5):1219-26. PubMed ID: 15096628
[TBL] [Abstract][Full Text] [Related]
5. A comparison of kinetic and regulatory properties of the tetrameric and dimeric forms of wild-type and Thr427-->Pro mutant human phenylalanine hydroxylase: contribution of the flexible hinge region Asp425-Gln429 to the tetramerization and cooperative substrate binding.
Bjørgo E; de Carvalho RM; Flatmark T
Eur J Biochem; 2001 Feb; 268(4):997-1005. PubMed ID: 11179966
[TBL] [Abstract][Full Text] [Related]
6. Phosphorylation of recombinant human phenylalanine hydroxylase: effect on catalytic activity, substrate activation and protection against non-specific cleavage of the fusion protein by restriction protease.
Døskeland AP; Martinez A; Knappskog PM; Flatmark T
Biochem J; 1996 Jan; 313 ( Pt 2)(Pt 2):409-14. PubMed ID: 8573072
[TBL] [Abstract][Full Text] [Related]
7. Deamidations in recombinant human phenylalanine hydroxylase. Identification of labile asparagine residues and functional characterization of Asn --> Asp mutant forms.
Carvalho RN; Solstad T; Bjørgo E; Barroso JF; Flatmark T
J Biol Chem; 2003 Apr; 278(17):15142-52. PubMed ID: 12554741
[TBL] [Abstract][Full Text] [Related]
8. Probing the role of crystallographically defined/predicted hinge-bending regions in the substrate-induced global conformational transition and catalytic activation of human phenylalanine hydroxylase by single-site mutagenesis.
Stokka AJ; Carvalho RN; Barroso JF; Flatmark T
J Biol Chem; 2004 Jun; 279(25):26571-80. PubMed ID: 15060071
[TBL] [Abstract][Full Text] [Related]
9. Structural characterization of the N-terminal autoregulatory sequence of phenylalanine hydroxylase.
Horne J; Jennings IG; Teh T; Gooley PR; Kobe B
Protein Sci; 2002 Aug; 11(8):2041-7. PubMed ID: 12142458
[TBL] [Abstract][Full Text] [Related]
10. cAMP-specific phosphodiesterase HSPDE4D3 mutants which mimic activation and changes in rolipram inhibition triggered by protein kinase A phosphorylation of Ser-54: generation of a molecular model.
Hoffmann R; Wilkinson IR; McCallum JF; Engels P; Houslay MD
Biochem J; 1998 Jul; 333 ( Pt 1)(Pt 1):139-49. PubMed ID: 9639573
[TBL] [Abstract][Full Text] [Related]
11. Recombinant human phenylalanine hydroxylase: novel regulatory and structural properties.
Kowlessur D; Citron BA; Kaufman S
Arch Biochem Biophys; 1996 Sep; 333(1):85-95. PubMed ID: 8806757
[TBL] [Abstract][Full Text] [Related]
12. Deamidation of labile asparagine residues in the autoregulatory sequence of human phenylalanine hydroxylase.
Solstad T; Carvalho RN; Andersen OA; Waidelich D; Flatmark T
Eur J Biochem; 2003 Mar; 270(5):929-38. PubMed ID: 12603326
[TBL] [Abstract][Full Text] [Related]
13. Essential role of the N-terminal autoregulatory sequence in the regulation of phenylalanine hydroxylase.
Jennings IG; Teh T; Kobe B
FEBS Lett; 2001 Jan; 488(3):196-200. PubMed ID: 11163771
[TBL] [Abstract][Full Text] [Related]
14. The active site residue tyrosine 325 influences iron binding and coupling efficiency in human phenylalanine hydroxylase.
Miranda FF; Kolberg M; Andersson KK; Geraldes CF; Martínez A
J Inorg Biochem; 2005 Jun; 99(6):1320-8. PubMed ID: 15917086
[TBL] [Abstract][Full Text] [Related]
15. Change in the N-terminal domain conformation of annexin I that correlates with liposome aggregation is impaired by Ser-27 to Glu mutation that mimics phosphorylation.
Porte F; de Santa Barbara P; Phalipou S; Liautard JP; Widada JS
Biochim Biophys Acta; 1996 Apr; 1293(2):177-84. PubMed ID: 8620027
[TBL] [Abstract][Full Text] [Related]
16. Substrate-induced conformational transition in human phenylalanine hydroxylase as studied by surface plasmon resonance analyses: the effect of terminal deletions, substrate analogues and phosphorylation.
Stokka AJ; Flatmark T
Biochem J; 2003 Feb; 369(Pt 3):509-18. PubMed ID: 12379147
[TBL] [Abstract][Full Text] [Related]
17. Electrostatic activation of rat phenylalanine hydroxylase.
Citron BA; Davis MD; Kaufman S
Biochem Biophys Res Commun; 1994 Jan; 198(1):174-80. PubMed ID: 7904815
[TBL] [Abstract][Full Text] [Related]
18. Partial characterization and three-dimensional-structural localization of eight mutations in exon 7 of the human phenylalanine hydroxylase gene associated with phenylketonuria.
Bjørgo E; Knappskog PM; Martinez A; Stevens RC; Flatmark T
Eur J Biochem; 1998 Oct; 257(1):1-10. PubMed ID: 9799096
[TBL] [Abstract][Full Text] [Related]
19. Structure/function relationships in human phenylalanine hydroxylase. Effect of terminal deletions on the oligomerization, activation and cooperativity of substrate binding to the enzyme.
Knappskog PM; Flatmark T; Aarden JM; Haavik J; Martínez A
Eur J Biochem; 1996 Dec; 242(3):813-21. PubMed ID: 9022714
[TBL] [Abstract][Full Text] [Related]
20. Molecular characterization of human stathmin expressed in Escherichia coli: site-directed mutagenesis of two phosphorylatable serines (Ser-25 and Ser-63).
Curmi PA; Maucuer A; Asselin S; Lecourtois M; Chaffotte A; Schmitter JM; Sobel A
Biochem J; 1994 Jun; 300 ( Pt 2)(Pt 2):331-8. PubMed ID: 8002936
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
