BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

108 related articles for article (PubMed ID: 12186544)

  • 21. Proprotein convertases in amphioxus: predicted structure and expression of proteases SPC2 and SPC3.
    Oliva AA; Steiner DF; Chan SJ
    Proc Natl Acad Sci U S A; 1995 Apr; 92(8):3591-5. PubMed ID: 7724604
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Site-directed mutagenesis and yeast two-hybrid studies of the insulin and insulin-like growth factor-1 receptors: the Src homology-2 domain-containing protein hGrb10 binds to the autophosphorylated tyrosine residues in the kinase domain of the insulin receptor.
    Dong LQ; Farris S; Christal J; Liu F
    Mol Endocrinol; 1997 Nov; 11(12):1757-65. PubMed ID: 9369444
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Hydroxyl group of insulin A19Tyr is essential for receptor binding: studies on (A19Phe)insulin.
    Du X; Tang JG
    Biochem Mol Biol Int; 1998 Jun; 45(2):255-60. PubMed ID: 9678246
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Importance of aliphatic side-chain structure at positions 2 and 3 of the insulin A chain in insulin-receptor interactions.
    Nakagawa SH; Tager HS
    Biochemistry; 1992 Mar; 31(12):3204-14. PubMed ID: 1554705
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Shortened insulin analogues: marked changes in biological activity resulting from replacement of TyrB26 and N-methylation of peptide bonds in the C-terminus of the B-chain.
    Záková L; Barth T; Jirácek J; Barthová J; Zórad S
    Biochemistry; 2004 Mar; 43(8):2323-31. PubMed ID: 14979729
    [TBL] [Abstract][Full Text] [Related]  

  • 26. The different folding behavior of insulin and insulin-like growth factor 1 is mainly controlled by their B-chain/domain.
    Guo ZY; Shen L; Feng YM
    Biochemistry; 2002 Feb; 41(5):1556-67. PubMed ID: 11814349
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Binding of mutant insulins to a mutated insulin receptor.
    Rafaeloff R; Yip CC; Goldfine ID
    Biochem Biophys Res Commun; 1992 Oct; 188(1):318-22. PubMed ID: 1329746
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Direct determination of the insulin-insulin receptor interface using transferred cross-saturation experiments.
    Nakamura T; Takahashi H; Takahashi M; Shimba N; Suzuki E; Shimada I
    J Med Chem; 2010 Mar; 53(5):1917-22. PubMed ID: 20158183
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Contribution of the residue Glu9, Glu46, and Phe49 to the biological activity of insulin-like growth factor-1.
    Chen H; Feng YM
    IUBMB Life; 2001 Jan; 51(1):33-7. PubMed ID: 11419693
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Ligand-induced activation of the insulin receptor: a multi-step process involving structural changes in both the ligand and the receptor.
    Ward CW; Lawrence MC
    Bioessays; 2009 Apr; 31(4):422-34. PubMed ID: 19274663
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Studies on receptor binding site of insulin: the hydrophobic B12Val can be substituted by hydrophilic thr.
    Wang QQ; Feng YM; Zhang YS
    Biochem Mol Biol Int; 1996 Aug; 39(6):1245-54. PubMed ID: 8876979
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Chiral mutagenesis of insulin's hidden receptor-binding surface: structure of an allo-isoleucine(A2) analogue.
    Xu B; Hua QX; Nakagawa SH; Jia W; Chu YC; Katsoyannis PG; Weiss MA
    J Mol Biol; 2002 Feb; 316(3):435-41. PubMed ID: 11866509
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Insulin analogs with B24 or B25 phenylalanine replaced by biphenylalanine.
    Du H; Shi J; Cui D; Zhang Y
    Acta Biochim Biophys Sin (Shanghai); 2008 Feb; 40(2):133-9. PubMed ID: 18235975
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Non-standard insulin design: structure-activity relationships at the periphery of the insulin receptor.
    Weiss MA; Wan Z; Zhao M; Chu YC; Nakagawa SH; Burke GT; Jia W; Hellmich R; Katsoyannis PG
    J Mol Biol; 2002 Jan; 315(2):103-11. PubMed ID: 11779231
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Molecular identification of an insulin growth factor binding protein (IGFBP) and its potential role in an insulin-like peptide system of the pearl oyster, Pinctada fucata.
    Zhang H; Shi Y; He M
    Comp Biochem Physiol B Biochem Mol Biol; 2017 Dec; 214():27-35. PubMed ID: 28939196
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Mutational analysis of invariant valine B12 in insulin: implications for receptor binding.
    Nakagawa SH; Tager HS; Steiner DF
    Biochemistry; 2000 Dec; 39(51):15826-35. PubMed ID: 11123908
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Interaction between the A2 and A19 amino acid residues is of critical importance for high biological activity in insulin: [19-leucine-A]insulin.
    Kitagawa K; Ogawa H; Burke GT; Chanley JD; Katsoyannis PG
    Biochemistry; 1984 Sep; 23(19):4444-8. PubMed ID: 6386048
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Complex with a phage display-derived peptide provides insight into the function of insulin-like growth factor I.
    Schaffer ML; Deshayes K; Nakamura G; Sidhu S; Skelton NJ
    Biochemistry; 2003 Aug; 42(31):9324-34. PubMed ID: 12899619
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Diabetes-associated mutations in human insulin: crystal structure and photo-cross-linking studies of a-chain variant insulin Wakayama.
    Wan ZL; Huang K; Xu B; Hu SQ; Wang S; Chu YC; Katsoyannis PG; Weiss MA
    Biochemistry; 2005 Apr; 44(13):5000-16. PubMed ID: 15794638
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Interaction mechanism of insulin-like peptide 5 with relaxin family peptide receptor 4.
    Hu MJ; Wei D; Shao XX; Wang JH; Liu YL; Xu ZG; Guo ZY
    Arch Biochem Biophys; 2017 Apr; 619():27-34. PubMed ID: 28274616
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 6.