353 related articles for article (PubMed ID: 12186904)
1. Subversion of cell signaling pathways by hepatitis C virus nonstructural 5A protein via interaction with Grb2 and P85 phosphatidylinositol 3-kinase.
He Y; Nakao H; Tan SL; Polyak SJ; Neddermann P; Vijaysri S; Jacobs BL; Katze MG
J Virol; 2002 Sep; 76(18):9207-17. PubMed ID: 12186904
[TBL] [Abstract][Full Text] [Related]
2. NS5A, a nonstructural protein of hepatitis C virus, binds growth factor receptor-bound protein 2 adaptor protein in a Src homology 3 domain/ligand-dependent manner and perturbs mitogenic signaling.
Tan SL; Nakao H; He Y; Vijaysri S; Neddermann P; Jacobs BL; Mayer BJ; Katze MG
Proc Natl Acad Sci U S A; 1999 May; 96(10):5533-8. PubMed ID: 10318918
[TBL] [Abstract][Full Text] [Related]
3. ERK negatively regulates the epidermal growth factor-mediated interaction of Gab1 and the phosphatidylinositol 3-kinase.
Yu CF; Liu ZX; Cantley LG
J Biol Chem; 2002 May; 277(22):19382-8. PubMed ID: 11896055
[TBL] [Abstract][Full Text] [Related]
4. Signaling complexes and protein-protein interactions involved in the activation of the Ras and phosphatidylinositol 3-kinase pathways by the c-Ret receptor tyrosine kinase.
Besset V; Scott RP; Ibáñez CF
J Biol Chem; 2000 Dec; 275(50):39159-66. PubMed ID: 10995764
[TBL] [Abstract][Full Text] [Related]
5. The neuron-specific Rai (ShcC) adaptor protein inhibits apoptosis by coupling Ret to the phosphatidylinositol 3-kinase/Akt signaling pathway.
Pelicci G; Troglio F; Bodini A; Melillo RM; Pettirossi V; Coda L; De Giuseppe A; Santoro M; Pelicci PG
Mol Cell Biol; 2002 Oct; 22(20):7351-63. PubMed ID: 12242309
[TBL] [Abstract][Full Text] [Related]
6. The multisubstrate adapter Gab1 regulates hepatocyte growth factor (scatter factor)-c-Met signaling for cell survival and DNA repair.
Fan S; Ma YX; Gao M; Yuan RQ; Meng Q; Goldberg ID; Rosen EM
Mol Cell Biol; 2001 Aug; 21(15):4968-84. PubMed ID: 11438654
[TBL] [Abstract][Full Text] [Related]
7. Activated STAT5 proteins induce activation of the PI 3-kinase/Akt and Ras/MAPK pathways via the Gab2 scaffolding adapter.
Nyga R; Pecquet C; Harir N; Gu H; Dhennin-Duthille I; Régnier A; Gouilleux-Gruart V; Lassoued K; Gouilleux F
Biochem J; 2005 Aug; 390(Pt 1):359-66. PubMed ID: 15833084
[TBL] [Abstract][Full Text] [Related]
8. Role of the Grb2-associated binder 1/SHP-2 interaction in cell growth and transformation.
Holgado-Madruga M; Wong AJ
Cancer Res; 2004 Mar; 64(6):2007-15. PubMed ID: 15026337
[TBL] [Abstract][Full Text] [Related]
9. Characterization of intracellular signals via tyrosine 1062 in RET activated by glial cell line-derived neurotrophic factor.
Hayashi H; Ichihara M; Iwashita T; Murakami H; Shimono Y; Kawai K; Kurokawa K; Murakumo Y; Imai T; Funahashi H; Nakao A; Takahashi M
Oncogene; 2000 Sep; 19(39):4469-75. PubMed ID: 11002419
[TBL] [Abstract][Full Text] [Related]
10. Receptor-specific regulation of phosphatidylinositol 3'-kinase activation by the protein tyrosine phosphatase Shp2.
Zhang SQ; Tsiaras WG; Araki T; Wen G; Minichiello L; Klein R; Neel BG
Mol Cell Biol; 2002 Jun; 22(12):4062-72. PubMed ID: 12024020
[TBL] [Abstract][Full Text] [Related]
11. Hepatitis C Virus Nonstructural 5A Protein Interacts with Abelson Interactor 1 and Modulates Epidermal Growth Factor-mediated MEK/ERK Signaling Pathway.
Huynh VT; Lim YS; Tran SC; Pham TM; Nguyen LN; Hwang SB
J Biol Chem; 2016 Oct; 291(43):22607-22617. PubMed ID: 27551040
[TBL] [Abstract][Full Text] [Related]
12. Morphine induces desensitization of insulin receptor signaling.
Li Y; Eitan S; Wu J; Evans CJ; Kieffer B; Sun X; Polakiewicz RD
Mol Cell Biol; 2003 Sep; 23(17):6255-66. PubMed ID: 12917346
[TBL] [Abstract][Full Text] [Related]
13. Hepatitis C virus NS5A activates the mammalian target of rapamycin (mTOR) pathway, contributing to cell survival by disrupting the interaction between FK506-binding protein 38 (FKBP38) and mTOR.
Peng L; Liang D; Tong W; Li J; Yuan Z
J Biol Chem; 2010 Jul; 285(27):20870-81. PubMed ID: 20439463
[TBL] [Abstract][Full Text] [Related]
14. 1Hepatitis C virus NS5A protein modulates c-Jun N-terminal kinase through interaction with tumor necrosis factor receptor-associated factor 2.
Park KJ; Choi SH; Choi DH; Park JM; Yie SW; Lee SY; Hwang SB
J Biol Chem; 2003 Aug; 278(33):30711-8. PubMed ID: 12796506
[TBL] [Abstract][Full Text] [Related]
15. Insulin-like growth factor-I stimulates Shc-dependent phosphatidylinositol 3-kinase activation via Grb2-associated p85 in vascular smooth muscle cells.
Radhakrishnan Y; Maile LA; Ling Y; Graves LM; Clemmons DR
J Biol Chem; 2008 Jun; 283(24):16320-31. PubMed ID: 18420583
[TBL] [Abstract][Full Text] [Related]
16. PACSIN2 Interacts with Nonstructural Protein 5A and Regulates Hepatitis C Virus Assembly.
Nguyen LP; Tran SC; Suetsugu S; Lim YS; Hwang SB
J Virol; 2020 Feb; 94(5):. PubMed ID: 31801866
[TBL] [Abstract][Full Text] [Related]
17. Biochemical and biological responses induced by coupling of Gab1 to phosphatidylinositol 3-kinase in RET-expressing cells.
Maeda K; Murakami H; Yoshida R; Ichihara M; Abe A; Hirai M; Murohara T; Takahashi M
Biochem Biophys Res Commun; 2004 Oct; 323(1):345-54. PubMed ID: 15351743
[TBL] [Abstract][Full Text] [Related]
18. The nonstructural NS5A protein of hepatitis C virus: an expanding, multifunctional role in enhancing hepatitis C virus pathogenesis.
Reyes GR
J Biomed Sci; 2002; 9(3):187-97. PubMed ID: 12065893
[TBL] [Abstract][Full Text] [Related]
19. Stimulation of phosphatidylinositol 3-kinase by fibroblast growth factor receptors is mediated by coordinated recruitment of multiple docking proteins.
Ong SH; Hadari YR; Gotoh N; Guy GR; Schlessinger J; Lax I
Proc Natl Acad Sci U S A; 2001 May; 98(11):6074-9. PubMed ID: 11353842
[TBL] [Abstract][Full Text] [Related]
20. Phosphorylation of the Grb2- and phosphatidylinositol 3-kinase p85-binding p36/38 by Syk in Lck-negative T cells.
von Willebrand M; Williams S; Tailor P; Mustelin T
Cell Signal; 1998 Jun; 10(6):407-13. PubMed ID: 9720763
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]