BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

301 related articles for article (PubMed ID: 12192082)

  • 21. Superior cytotoxicity with ganciclovir compared with acyclovir and 1-beta-D-arabinofuranosylthymine in herpes simplex virus-thymidine kinase-expressing cells: a novel paradigm for cell killing.
    Rubsam LZ; Davidson BL; Shewach DS
    Cancer Res; 1998 Sep; 58(17):3873-82. PubMed ID: 9731497
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Transduction of human pancreatic tumor cells with vesicular stomatitis virus G-pseudotyped retroviral vectors containing a herpes simplex virus thymidine kinase mutant gene enhances bystander effects and sensitivity to ganciclovir.
    Howard BD; Boenicke L; Schniewind B; Henne-Bruns D; Kalthoff H
    Cancer Gene Ther; 2000 Jun; 7(6):927-38. PubMed ID: 10880025
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Optimizing prostate cancer suicide gene therapy using herpes simplex virus thymidine kinase active site variants.
    Pantuck AJ; Matherly J; Zisman A; Nguyen D; Berger F; Gambhir SS; Black ME; Belldegrun A; Wu L
    Hum Gene Ther; 2002 May; 13(7):777-89. PubMed ID: 11975845
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Enhanced cytotoxicity of antiviral drugs mediated by adenovirus directed transfer of the herpes simplex virus thymidine kinase gene in rat glioma cells.
    Shewach DS; Zerbe LK; Hughes TL; Roessler BJ; Breakefield XO; Davidson BL
    Cancer Gene Ther; 1994 Jun; 1(2):107-12. PubMed ID: 7621241
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Differential ganciclovir-mediated cell killing by glutamine 125 mutants of herpes simplex virus type 1 thymidine kinase.
    Drake RR; Wilbert TN; Hinds TA; Gilbert KM
    J Biol Chem; 1999 Dec; 274(52):37186-92. PubMed ID: 10601281
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Polyamine biosynthesis inhibition enhances HSV-1 thymidine kinase/ganciclovir-mediated cytotoxicity in tumor cells.
    Pasanen T; Karppinen A; Alhonen L; Jänne J; Wahlfors J
    Int J Cancer; 2003 Apr; 104(3):380-8. PubMed ID: 12569563
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Molecular imaging with 123I-FIAU, 18F-FUdR, 18F-FET, and 18F-FDG for monitoring herpes simplex virus type 1 thymidine kinase and ganciclovir prodrug activation gene therapy of cancer.
    Wang HE; Yu HM; Liu RS; Lin M; Gelovani JG; Hwang JJ; Wei HJ; Deng WP
    J Nucl Med; 2006 Jul; 47(7):1161-71. PubMed ID: 16818951
    [TBL] [Abstract][Full Text] [Related]  

  • 28. A mutant herpes simplex virus type 1 thymidine kinase reporter gene shows improved sensitivity for imaging reporter gene expression with positron emission tomography.
    Gambhir SS; Bauer E; Black ME; Liang Q; Kokoris MS; Barrio JR; Iyer M; Namavari M; Phelps ME; Herschman HR
    Proc Natl Acad Sci U S A; 2000 Mar; 97(6):2785-90. PubMed ID: 10716999
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Mutation of Gln125 to Asn selectively abolishes the thymidylate kinase activity of herpes simplex virus type 1 thymidine kinase.
    Degrève B; Esnouf R; De Clercq E; Balzarini J
    Mol Pharmacol; 2001 Feb; 59(2):285-93. PubMed ID: 11160865
    [TBL] [Abstract][Full Text] [Related]  

  • 30. The Epstein-Barr virus (EBV)-encoded protein kinase, EBV-PK, but not the thymidine kinase (EBV-TK), is required for ganciclovir and acyclovir inhibition of lytic viral production.
    Meng Q; Hagemeier SR; Fingeroth JD; Gershburg E; Pagano JS; Kenney SC
    J Virol; 2010 May; 84(9):4534-42. PubMed ID: 20181711
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Importance of C-terminus of herpes simplex virus type 1 thymidine kinase for maintaining thymidine kinase and acyclovir-phosphorylation activities.
    Saijo M; Suzutani T; Niikura M; Morikawa S; Kurane I
    J Med Virol; 2002 Mar; 66(3):388-93. PubMed ID: 11793392
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Analysis of the thymidine kinase of a herpes simplex virus type 1 isolate that exhibits resistance to (E)-5-(2-bromovinyl)-2'-deoxyuridine.
    Wilber BA; Docherty JJ
    J Gen Virol; 1994 Jul; 75 ( Pt 7)():1743-7. PubMed ID: 8021603
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Human herpesvirus 8 open reading frame 21 is a thymidine and thymidylate kinase of narrow substrate specificity that efficiently phosphorylates zidovudine but not ganciclovir.
    Gustafson EA; Schinazi RF; Fingeroth JD
    J Virol; 2000 Jan; 74(2):684-92. PubMed ID: 10623730
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Synergy between the herpes simplex virus tk/ganciclovir prodrug suicide system and the topoisomerase I inhibitor topotecan.
    Wildner O; Blaese RM; Morris JC
    Hum Gene Ther; 1999 Nov; 10(16):2679-87. PubMed ID: 10566896
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Efficacy of adenovirus-mediated CD/5-FC and HSV-1 thymidine kinase/ganciclovir suicide gene therapies concomitant with p53 gene therapy.
    Xie Y; Gilbert JD; Kim JH; Freytag SO
    Clin Cancer Res; 1999 Dec; 5(12):4224-32. PubMed ID: 10632364
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Liposomal encapsulation of ganciclovir enhances the efficacy of herpes simplex virus type 1 thymidine kinase suicide gene therapy against hepatic tumors in rats.
    Engelmann C; Panis Y; Bolard J; Diquet B; Fabre M; Nagy H; Soubrane O; Houssin D; Klatzmann D
    Hum Gene Ther; 1999 Jun; 10(9):1545-51. PubMed ID: 10395379
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Coexpression of guanylate kinase with thymidine kinase enhances prodrug cell killing in vitro and suppresses vascular smooth muscle cell proliferation in vivo.
    Akyürek LM; Nallamshetty S; Aoki K; San H; Yang ZY; Nabel GJ; Nabel EG
    Mol Ther; 2001 May; 3(5 Pt 1):779-86. PubMed ID: 11356082
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Analysis of antiviral drug properties of thymidine kinase of herpes B virus using recombinant herpes simplex virus 1.
    Nguyen PHA; Fukushi S; Yamada S; Harada S; Yoshikawa T; Kinoshita H; Kawahara M; Ogawa T; Ebihara H; Moi ML; Saijo M
    Microbiol Spectr; 2024 Jan; 12(1):e0309123. PubMed ID: 38095468
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Effects of mutations on herpes simplex virus 1 thymidine kinase functionality: an in vitro assay based on detection of monophosphate forms of acyclovir and thymidine using HPLC/DAD.
    Malartre N; Boulieu R; Falah N; Cortay JC; Lina B; Morfin F; Frobert E
    Antiviral Res; 2012 Sep; 95(3):224-8. PubMed ID: 22796575
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Potentiation of ganciclovir toxicity in the herpes simplex virus thymidine kinase/ganciclovir administration system by ponicidin.
    Hayashi K; Hayashi T; Sun HD; Takeda Y
    Cancer Gene Ther; 2000 Jan; 7(1):45-52. PubMed ID: 10678355
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 16.