BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

334 related articles for article (PubMed ID: 12193602)

  • 1. Probing the molecular basis for potent and selective protein-tyrosine phosphatase 1B inhibition.
    Guo XL; Shen K; Wang F; Lawrence DS; Zhang ZY
    J Biol Chem; 2002 Oct; 277(43):41014-22. PubMed ID: 12193602
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Crystal structure of PTP1B complexed with a potent and selective bidentate inhibitor.
    Sun JP; Fedorov AA; Lee SY; Guo XL; Shen K; Lawrence DS; Almo SC; Zhang ZY
    J Biol Chem; 2003 Apr; 278(14):12406-14. PubMed ID: 12547827
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Allele-specific inhibitors of protein tyrosine phosphatases.
    Hoffman HE; Blair ER; Johndrow JE; Bishop AC
    J Am Chem Soc; 2005 Mar; 127(9):2824-5. PubMed ID: 15740097
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Steric hindrance as a basis for structure-based design of selective inhibitors of protein-tyrosine phosphatases.
    Iversen LF; Andersen HS; Møller KB; Olsen OH; Peters GH; Branner S; Mortensen SB; Hansen TK; Lau J; Ge Y; Holsworth DD; Newman MJ; Hundahl Møller NP
    Biochemistry; 2001 Dec; 40(49):14812-20. PubMed ID: 11732900
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A novel strategy for the development of selective active-site inhibitors of the protein tyrosine phosphatase-like proteins islet-cell antigen 512 (IA-2) and phogrin (IA-2beta).
    Drake PG; Peters GH; Andersen HS; Hendriks W; Møller NP
    Biochem J; 2003 Jul; 373(Pt 2):393-401. PubMed ID: 12697028
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Molecular dynamics simulations of interaction between protein-tyrosine phosphatase 1B and a bidentate inhibitor.
    Liu GX; Tan JZ; Niu CY; Shen JH; Luo XM; Shen X; Chen KX; Jiang HL
    Acta Pharmacol Sin; 2006 Jan; 27(1):100-10. PubMed ID: 16364216
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Discovery of a potent, selective protein tyrosine phosphatase 1B inhibitor using a linked-fragment strategy.
    Szczepankiewicz BG; Liu G; Hajduk PJ; Abad-Zapatero C; Pei Z; Xin Z; Lubben TH; Trevillyan JM; Stashko MA; Ballaron SJ; Liang H; Huang F; Hutchins CW; Fesik SW; Jirousek MR
    J Am Chem Soc; 2003 Apr; 125(14):4087-96. PubMed ID: 12670229
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Drugging the Undruggable: Therapeutic Potential of Targeting Protein Tyrosine Phosphatases.
    Zhang ZY
    Acc Chem Res; 2017 Jan; 50(1):122-129. PubMed ID: 27977138
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Generation of inhibitor-sensitive protein tyrosine phosphatases via active-site mutations.
    Bishop AC; Zhang XY; Lone AM
    Methods; 2007 Jul; 42(3):278-88. PubMed ID: 17532515
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Recent development of small molecular specific inhibitor of protein tyrosine phosphatase 1B.
    Lee S; Wang Q
    Med Res Rev; 2007 Jul; 27(4):553-73. PubMed ID: 17039461
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Protein-tyrosine phosphatases: structure, mechanism, and inhibitor discovery.
    Burke TR; Zhang ZY
    Biopolymers; 1998; 47(3):225-41. PubMed ID: 9817026
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Functional studies of protein tyrosine phosphatases with chemical approaches.
    Zhang ZY
    Biochim Biophys Acta; 2005 Dec; 1754(1-2):100-7. PubMed ID: 16226063
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cellular inhibition of protein tyrosine phosphatase 1B by uncharged thioxothiazolidinone derivatives.
    Stuible M; Zhao L; Aubry I; Schmidt-Arras D; Böhmer FD; Li CJ; Tremblay ML
    Chembiochem; 2007 Jan; 8(2):179-86. PubMed ID: 17191286
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Bidentate inhibitors of protein tyrosine phosphatases.
    Low JL; Chai CL; Yao SQ
    Antioxid Redox Signal; 2014 May; 20(14):2225-50. PubMed ID: 24206395
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Residues distant from the active site influence protein-tyrosine phosphatase 1B inhibitor binding.
    Montalibet J; Skorey K; McKay D; Scapin G; Asante-Appiah E; Kennedy BP
    J Biol Chem; 2006 Feb; 281(8):5258-66. PubMed ID: 16332678
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Small molecule tools for functional interrogation of protein tyrosine phosphatases.
    He R; Zeng LF; He Y; Zhang S; Zhang ZY
    FEBS J; 2013 Jan; 280(2):731-50. PubMed ID: 22816879
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Protein tyrosine phosphatases: structure and function, substrate specificity, and inhibitor development.
    Zhang ZY
    Annu Rev Pharmacol Toxicol; 2002; 42():209-34. PubMed ID: 11807171
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Chemical and mechanistic approaches to the study of protein tyrosine phosphatases.
    Zhang ZY
    Acc Chem Res; 2003 Jun; 36(6):385-92. PubMed ID: 12809524
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Peptidyl aldehydes as reversible covalent inhibitors of protein tyrosine phosphatases.
    Fu H; Park J; Pei D
    Biochemistry; 2002 Aug; 41(34):10700-9. PubMed ID: 12186556
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Effects of SOV-induced phosphatase inhibition and expression of protein tyrosine phosphatases in rat corneal endothelial cells.
    Chen WL; Harris DL; Joyce NC
    Exp Eye Res; 2005 Nov; 81(5):570-80. PubMed ID: 15950220
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.