187 related articles for article (PubMed ID: 12196022)
1. An unexpected interaction between the modular polyketide synthases, erythromycin DEBS1 and pikromycin PikAIV, leads to efficient triketide lactone synthesis.
Kim BS; Cropp TA; Florova G; Lindsay Y; Sherman DH; Reynolds KA
Biochemistry; 2002 Sep; 41(35):10827-33. PubMed ID: 12196022
[TBL] [Abstract][Full Text] [Related]
2. Mechanisms of molecular recognition in the pikromycin polyketide synthase.
Chen S; Xue Y; Sherman DH; Reynolds KA
Chem Biol; 2000 Dec; 7(12):907-18. PubMed ID: 11137814
[TBL] [Abstract][Full Text] [Related]
3. The hidden steps of domain skipping: macrolactone ring size determination in the pikromycin modular polyketide synthase.
Beck BJ; Yoon YJ; Reynolds KA; Sherman DH
Chem Biol; 2002 May; 9(5):575-83. PubMed ID: 12031664
[TBL] [Abstract][Full Text] [Related]
4. Iterative chain elongation by a pikromycin monomodular polyketide synthase.
Beck BJ; Aldrich CC; Fecik RA; Reynolds KA; Sherman DH
J Am Chem Soc; 2003 Apr; 125(16):4682-3. PubMed ID: 12696866
[TBL] [Abstract][Full Text] [Related]
5. Active-site residue, domain and module swaps in modular polyketide synthases.
Del Vecchio F; Petkovic H; Kendrew SG; Low L; Wilkinson B; Lill R; Cortés J; Rudd BA; Staunton J; Leadlay PF
J Ind Microbiol Biotechnol; 2003 Aug; 30(8):489-94. PubMed ID: 12811585
[TBL] [Abstract][Full Text] [Related]
6. Chain initiation on the soraphen-producing modular polyketide synthase from Sorangium cellulosum.
Wilkinson CJ; Frost EJ; Staunton J; Leadlay PF
Chem Biol; 2001 Dec; 8(12):1197-208. PubMed ID: 11755398
[TBL] [Abstract][Full Text] [Related]
7. Functional modular dissection of DEBS1-TE changes triketide lactone ratios and provides insight into Acyl group loading, hydrolysis, and ACP transfer.
Yan J; Hazzard C; Bonnett SA; Reynolds KA
Biochemistry; 2012 Nov; 51(46):9333-41. PubMed ID: 23116287
[TBL] [Abstract][Full Text] [Related]
8. Biochemical evidence for an editing role of thioesterase II in the biosynthesis of the polyketide pikromycin.
Kim BS; Cropp TA; Beck BJ; Sherman DH; Reynolds KA
J Biol Chem; 2002 Dec; 277(50):48028-34. PubMed ID: 12368286
[TBL] [Abstract][Full Text] [Related]
9. Acyltransferase domain substitutions in erythromycin polyketide synthase yield novel erythromycin derivatives.
Ruan X; Pereda A; Stassi DL; Zeidner D; Summers RG; Jackson M; Shivakumar A; Kakavas S; Staver MJ; Donadio S; Katz L
J Bacteriol; 1997 Oct; 179(20):6416-25. PubMed ID: 9335291
[TBL] [Abstract][Full Text] [Related]
10. Substrate recognition and channeling of monomodules from the pikromycin polyketide synthase.
Beck BJ; Aldrich CC; Fecik RA; Reynolds KA; Sherman DH
J Am Chem Soc; 2003 Oct; 125(41):12551-7. PubMed ID: 14531700
[TBL] [Abstract][Full Text] [Related]
11. The Streptomyces venezuelae pikAV gene contains a transcription unit essential for expression of enzymes involved in glycosylation of narbonolide and 10-deoxymethynolide.
Chen S; Roberts JB; Xue Y; Sherman DH; Reynolds KA
Gene; 2001 Jan; 263(1-2):255-64. PubMed ID: 11223265
[TBL] [Abstract][Full Text] [Related]
12. Alternative modular polyketide synthase expression controls macrolactone structure.
Xue Y; Sherman DH
Nature; 2000 Feb; 403(6769):571-5. PubMed ID: 10676969
[TBL] [Abstract][Full Text] [Related]
13. Polyketide synthesis in vitro on a modular polyketide synthase.
Wiesmann KE; Cortés J; Brown MJ; Cutter AL; Staunton J; Leadlay PF
Chem Biol; 1995 Sep; 2(9):583-9. PubMed ID: 9383462
[TBL] [Abstract][Full Text] [Related]
14. A hybrid modular polyketide synthase obtained by domain swapping.
Oliynyk M; Brown MJ; Cortés J; Staunton J; Leadlay PF
Chem Biol; 1996 Oct; 3(10):833-9. PubMed ID: 8939702
[TBL] [Abstract][Full Text] [Related]
15. Engineering broader specificity into an antibiotic-producing polyketide synthase.
Marsden AF; Wilkinson B; Cortés J; Dunster NJ; Staunton J; Leadlay PF
Science; 1998 Jan; 279(5348):199-202. PubMed ID: 9422686
[TBL] [Abstract][Full Text] [Related]
16. Interrogating the molecular basis for multiple macrolactone ring formation by the pikromycin polyketide synthase.
Kittendorf JD; Beck BJ; Buchholz TJ; Seufert W; Sherman DH
Chem Biol; 2007 Aug; 14(8):944-54. PubMed ID: 17719493
[TBL] [Abstract][Full Text] [Related]
17. Repositioning of a domain in a modular polyketide synthase to promote specific chain cleavage.
Cortes J; Wiesmann KE; Roberts GA; Brown MJ; Staunton J; Leadlay PF
Science; 1995 Jun; 268(5216):1487-9. PubMed ID: 7770773
[TBL] [Abstract][Full Text] [Related]
18. Engineering specificity of starter unit selection by the erythromycin-producing polyketide synthase.
Long PF; Wilkinson CJ; Bisang CP; Cortés J; Dunster N; Oliynyk M; McCormick E; McArthur H; Mendez C; Salas JA; Staunton J; Leadlay PF
Mol Microbiol; 2002 Mar; 43(5):1215-25. PubMed ID: 11918808
[TBL] [Abstract][Full Text] [Related]
19. Elucidating the mechanism of chain termination switching in the picromycin/methymycin polyketide synthase.
Tang L; Fu H; Betlach MC; McDaniel R
Chem Biol; 1999 Aug; 6(8):553-8. PubMed ID: 10421766
[TBL] [Abstract][Full Text] [Related]
20. Precursor-directed biosynthesis of novel triketide lactones.
Regentin R; Kennedy J; Wu N; Carney JR; Licari P; Galazzo J; Desai R
Biotechnol Prog; 2004; 20(1):122-7. PubMed ID: 14763833
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
