BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

189 related articles for article (PubMed ID: 12196149)

  • 1. Controlling the reactivity of radical intermediates by coenzyme B(12)-dependent methylmalonyl-CoA mutase.
    Banerjee R; Vlasie M
    Biochem Soc Trans; 2002 Aug; 30(4):621-4. PubMed ID: 12196149
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Characterization of a succinyl-CoA radical-cob(II)alamin spin triplet intermediate in the reaction catalyzed by adenosylcobalamin-dependent methylmalonyl-CoA mutase.
    Mansoorabadi SO; Padmakumar R; Fazliddinova N; Vlasie M; Banerjee R; Reed GH
    Biochemistry; 2005 Mar; 44(9):3153-8. PubMed ID: 15736925
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The synthetic substrate succinyl(carbadethia)-CoA generates cob(II)alamin on adenosylcobalamin-dependent methylmalonyl-CoA mutase.
    Keep NH; Smith GA; Evans MC; Diakun GP; Leadlay PF
    Biochem J; 1993 Oct; 295 ( Pt 2)(Pt 2):387-92. PubMed ID: 7902085
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Conformational changes on substrate binding to methylmalonyl CoA mutase and new insights into the free radical mechanism.
    Mancia F; Evans PR
    Structure; 1998 Jun; 6(6):711-20. PubMed ID: 9655823
    [TBL] [Abstract][Full Text] [Related]  

  • 5. When a spectator turns killer: suicidal electron transfer from cobalamin in methylmalonyl-CoA mutase.
    Vlasie MD; Banerjee R
    Biochemistry; 2004 Jul; 43(26):8410-7. PubMed ID: 15222752
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Alternative pathways for radical dissipation in an active site mutant of B12-dependent methylmalonyl-CoA mutase.
    Padovani D; Banerjee R
    Biochemistry; 2006 Mar; 45(9):2951-9. PubMed ID: 16503649
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Stabilization of radical intermediates by an active-site tyrosine residue in methylmalonyl-CoA mutase.
    Thomä NH; Meier TW; Evans PR; Leadlay PF
    Biochemistry; 1998 Oct; 37(41):14386-93. PubMed ID: 9772164
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Protection of radical intermediates at the active site of adenosylcobalamin-dependent methylmalonyl-CoA mutase.
    Thomä NH; Evans PR; Leadlay PF
    Biochemistry; 2000 Aug; 39(31):9213-21. PubMed ID: 10924114
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Solvent polarity effects and limited acid catalysis in rearrangements of model radicals for the methylmalonyl-CoA mutase- and isobutyryl-CoA mutase-catalyzed isomerization reactions.
    Daublain P; Horner JH; Kuznetsov A; Newcomb M
    J Am Chem Soc; 2004 May; 126(17):5368-9. PubMed ID: 15113202
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Tritium isotope effects in adenosylcobalamin-dependent methylmalonyl-CoA mutase.
    Meier TW; Thomä NH; Leadlay PF
    Biochemistry; 1996 Sep; 35(36):11791-6. PubMed ID: 8794760
    [TBL] [Abstract][Full Text] [Related]  

  • 11. How coenzyme B12 radicals are generated: the crystal structure of methylmalonyl-coenzyme A mutase at 2 A resolution.
    Mancia F; Keep NH; Nakagawa A; Leadlay PF; McSweeney S; Rasmussen B; Bösecke P; Diat O; Evans PR
    Structure; 1996 Mar; 4(3):339-50. PubMed ID: 8805541
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Evidence that cobalt-carbon bond homolysis is coupled to hydrogen atom abstraction from substrate in methylmalonyl-CoA mutase.
    Padmakumar R; Padmakumar R; Banerjee R
    Biochemistry; 1997 Mar; 36(12):3713-8. PubMed ID: 9132024
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The elusive 5'-deoxyadenosyl radical in coenzyme-B12-mediated reactions.
    Bucher D; Sandala GM; Durbeej B; Radom L; Smith DM
    J Am Chem Soc; 2012 Jan; 134(3):1591-9. PubMed ID: 22229941
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Molecular basis for dysfunction of some mutant forms of methylmalonyl-CoA mutase: deductions from the structure of methionine synthase.
    Drennan CL; Matthews RG; Rosenblatt DS; Ledley FD; Fenton WA; Ludwig ML
    Proc Natl Acad Sci U S A; 1996 May; 93(11):5550-5. PubMed ID: 8643613
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The error in the cryptic stereospecificity of methylmalonyl-CoA mutase. The use of carba-(dethia)-coenzyme A substrate analogues gives new insight into the enzyme mechanism.
    Hull WE; Michenfelder M; Rétey J
    Eur J Biochem; 1988 Apr; 173(1):191-201. PubMed ID: 2895708
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Epimerase (Msed_0639) and mutase (Msed_0638 and Msed_2055) convert (S)-methylmalonyl-coenzyme A (CoA) to succinyl-CoA in the Metallosphaera sedula 3-hydroxypropionate/4-hydroxybutyrate cycle.
    Han Y; Hawkins AS; Adams MW; Kelly RM
    Appl Environ Microbiol; 2012 Sep; 78(17):6194-202. PubMed ID: 22752162
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Proton transfer from histidine 244 may facilitate the 1,2 rearrangement reaction in coenzyme B(12)-dependent methylmalonyl-CoA mutase.
    Maiti N; Widjaja L; Banerjee R
    J Biol Chem; 1999 Nov; 274(46):32733-7. PubMed ID: 10551831
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Energetic and stereochemical effects of the protein environment on substrate: a theoretical study of methylmalonyl-CoA mutase.
    Loferer MJ; Webb BM; Grant GH; Liedl KR
    J Am Chem Soc; 2003 Jan; 125(4):1072-8. PubMed ID: 12537507
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Thermodynamic and kinetic characterization of Co-C bond homolysis catalyzed by coenzyme B(12)-dependent methylmalonyl-CoA mutase.
    Chowdhury S; Banerjee R
    Biochemistry; 2000 Jul; 39(27):7998-8006. PubMed ID: 10891081
    [TBL] [Abstract][Full Text] [Related]  

  • 20. On the mechanism of action of methylmalonyl-CoA mutase. Change of the steric course on isotope substitution.
    Wölfle K; Michenfelder M; König A; Hull WE; Rétey J
    Eur J Biochem; 1986 May; 156(3):545-54. PubMed ID: 2870921
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.