451 related articles for article (PubMed ID: 12196628)
21. Mechanistic insights into specificity, activity, and regulatory elements of the regulator of G-protein signaling (RGS)-containing Rho-specific guanine nucleotide exchange factors (GEFs) p115, PDZ-RhoGEF (PRG), and leukemia-associated RhoGEF (LARG).
Jaiswal M; Gremer L; Dvorsky R; Haeusler LC; Cirstea IC; Uhlenbrock K; Ahmadian MR
J Biol Chem; 2011 May; 286(20):18202-12. PubMed ID: 21454492
[TBL] [Abstract][Full Text] [Related]
22. Leukemia-associated Rho guanine nucleotide exchange factor (LARG) links heterotrimeric G proteins of the G(12) family to Rho.
Fukuhara S; Chikumi H; Gutkind JS
FEBS Lett; 2000 Nov; 485(2-3):183-8. PubMed ID: 11094164
[TBL] [Abstract][Full Text] [Related]
23. Characterization of the expression of PDZ-RhoGEF, LARG and G(alpha)12/G(alpha)13 proteins in the murine nervous system.
Kuner R; Swiercz JM; Zywietz A; Tappe A; Offermanns S
Eur J Neurosci; 2002 Dec; 16(12):2333-41. PubMed ID: 12492428
[TBL] [Abstract][Full Text] [Related]
24. Agonist-induced Ca2+ sensitization in smooth muscle: redundancy of Rho guanine nucleotide exchange factors (RhoGEFs) and response kinetics, a caged compound study.
Artamonov MV; Momotani K; Stevenson A; Trentham DR; Derewenda U; Derewenda ZS; Read PW; Gutkind JS; Somlyo AV
J Biol Chem; 2013 Nov; 288(47):34030-34040. PubMed ID: 24106280
[TBL] [Abstract][Full Text] [Related]
25. Structural determinants of RhoA binding and nucleotide exchange in leukemia-associated Rho guanine-nucleotide exchange factor.
Kristelly R; Gao G; Tesmer JJ
J Biol Chem; 2004 Nov; 279(45):47352-62. PubMed ID: 15331592
[TBL] [Abstract][Full Text] [Related]
26. The molecular basis of RhoA specificity in the guanine nucleotide exchange factor PDZ-RhoGEF.
Oleksy A; Opaliński Ł; Derewenda U; Derewenda ZS; Otlewski J
J Biol Chem; 2006 Oct; 281(43):32891-7. PubMed ID: 16954208
[TBL] [Abstract][Full Text] [Related]
27. PDZ-RhoGEF and LARG are essential for embryonic development and provide a link between thrombin and LPA receptors and Rho activation.
Mikelis CM; Palmby TR; Simaan M; Li W; Szabo R; Lyons R; Martin D; Yagi H; Fukuhara S; Chikumi H; Galisteo R; Mukouyama YS; Bugge TH; Gutkind JS
J Biol Chem; 2013 Apr; 288(17):12232-43. PubMed ID: 23467409
[TBL] [Abstract][Full Text] [Related]
28. Physical and functional interactions of the lysophosphatidic acid receptors with PDZ domain-containing Rho guanine nucleotide exchange factors (RhoGEFs).
Yamada T; Ohoka Y; Kogo M; Inagaki S
J Biol Chem; 2005 May; 280(19):19358-63. PubMed ID: 15755723
[TBL] [Abstract][Full Text] [Related]
29. The Semaphorin 4D-RhoA-Akt Signal Cascade Regulates Enamel Matrix Secretion in Coordination With Cell Polarization During Ameloblast Differentiation.
Otsu K; Ida-Yonemochi H; Fujiwara N; Harada H
J Bone Miner Res; 2016 Nov; 31(11):1943-1954. PubMed ID: 27218883
[TBL] [Abstract][Full Text] [Related]
30. Plexin-A1 and plexin-B1 specifically interact at their cytoplasmic domains.
Usui H; Taniguchi M; Yokomizo T; Shimizu T
Biochem Biophys Res Commun; 2003 Jan; 300(4):927-31. PubMed ID: 12559962
[TBL] [Abstract][Full Text] [Related]
31. Binding of PDZ-RhoGEF to ATP-binding cassette transporter A1 (ABCA1) induces cholesterol efflux through RhoA activation and prevention of transporter degradation.
Okuhira K; Fitzgerald ML; Tamehiro N; Ohoka N; Suzuki K; Sawada J; Naito M; Nishimaki-Mogami T
J Biol Chem; 2010 May; 285(21):16369-77. PubMed ID: 20348106
[TBL] [Abstract][Full Text] [Related]
32. Secondary PDZ domain-binding site on class B plexins enhances the affinity for PDZ-RhoGEF.
Pascoe HG; Gutowski S; Chen H; Brautigam CA; Chen Z; Sternweis PC; Zhang X
Proc Natl Acad Sci U S A; 2015 Dec; 112(48):14852-7. PubMed ID: 26627240
[TBL] [Abstract][Full Text] [Related]
33. Leukemia-associated Rho guanine nucleotide exchange factor, a Dbl family protein found mutated in leukemia, causes transformation by activation of RhoA.
Reuther GW; Lambert QT; Booden MA; Wennerberg K; Becknell B; Marcucci G; Sondek J; Caligiuri MA; Der CJ
J Biol Chem; 2001 Jul; 276(29):27145-51. PubMed ID: 11373293
[TBL] [Abstract][Full Text] [Related]
34. Molecular dissection of the semaphorin 4D receptor plexin-B1-stimulated R-Ras GTPase-activating protein activity and neurite remodeling in hippocampal neurons.
Oinuma I; Katoh H; Negishi M
J Neurosci; 2004 Dec; 24(50):11473-80. PubMed ID: 15601954
[TBL] [Abstract][Full Text] [Related]
35. Crystal structure of the plexin A3 intracellular region reveals an autoinhibited conformation through active site sequestration.
He H; Yang T; Terman JR; Zhang X
Proc Natl Acad Sci U S A; 2009 Sep; 106(37):15610-5. PubMed ID: 19717441
[TBL] [Abstract][Full Text] [Related]
36. Degenerate specificity of PDZ domains from RhoA-specific nucleotide exchange factors PDZRhoGEF and LARG.
Smietana K; Kasztura M; Paduch M; Derewenda U; Derewenda ZS; Otlewski J
Acta Biochim Pol; 2008; 55(2):269-80. PubMed ID: 18542831
[TBL] [Abstract][Full Text] [Related]
37. Modular architecture and novel protein-protein interactions regulating the RGS-containing Rho guanine nucleotide exchange factors.
Vázquez-Prado J; Basile J; Gutkind JS
Methods Enzymol; 2004; 390():259-85. PubMed ID: 15488183
[TBL] [Abstract][Full Text] [Related]
38. Regulation of G protein-linked guanine nucleotide exchange factors for Rho, PDZ-RhoGEF, and LARG by tyrosine phosphorylation: evidence of a role for focal adhesion kinase.
Chikumi H; Fukuhara S; Gutkind JS
J Biol Chem; 2002 Apr; 277(14):12463-73. PubMed ID: 11799111
[TBL] [Abstract][Full Text] [Related]
39. Real-time NMR study of guanine nucleotide exchange and activation of RhoA by PDZ-RhoGEF.
Gasmi-Seabrook GM; Marshall CB; Cheung M; Kim B; Wang F; Jang YJ; Mak TW; Stambolic V; Ikura M
J Biol Chem; 2010 Feb; 285(8):5137-45. PubMed ID: 20018869
[TBL] [Abstract][Full Text] [Related]
40. Sphingosine 1-phosphate receptor 2 signals through leukemia-associated RhoGEF (LARG), to promote smooth muscle cell differentiation.
Medlin MD; Staus DP; Dubash AD; Taylor JM; Mack CP
Arterioscler Thromb Vasc Biol; 2010 Sep; 30(9):1779-86. PubMed ID: 20702813
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
