BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

148 related articles for article (PubMed ID: 12198119)

  • 1. Differential cytostatic and apoptotic effects of ecteinascidin-743 in cancer cells. Transcription-dependent cell cycle arrest and transcription-independent JNK and mitochondrial mediated apoptosis.
    Gajate C; An F; Mollinedo F
    J Biol Chem; 2002 Nov; 277(44):41580-9. PubMed ID: 12198119
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Rapid and selective apoptosis in human leukemic cells induced by Aplidine through a Fas/CD95- and mitochondrial-mediated mechanism.
    Gajate C; An F; Mollinedo F
    Clin Cancer Res; 2003 Apr; 9(4):1535-45. PubMed ID: 12684430
    [TBL] [Abstract][Full Text] [Related]  

  • 3. [The role of mitogen-activated protein kinase cascades in inhibition of proliferation in human prostate carcinoma cells by raloxifene: an in vitro experiment].
    Zhang YX; Kong CZ
    Zhonghua Yi Xue Za Zhi; 2008 Jan; 88(4):271-5. PubMed ID: 18361842
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Induction of apoptosis in leukemic cells by the reversible microtubule-disrupting agent 2-methoxy-5-(2',3',4'-trimethoxyphenyl)-2,4,6-cycloheptatrien-1 -one: protection by Bcl-2 and Bcl-X(L) and cell cycle arrest.
    Gajate C; Barasoain I; Andreu JM; Mollinedo F
    Cancer Res; 2000 May; 60(10):2651-9. PubMed ID: 10825137
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Asiatic acid, a triterpene, induces apoptosis and cell cycle arrest through activation of extracellular signal-regulated kinase and p38 mitogen-activated protein kinase pathways in human breast cancer cells.
    Hsu YL; Kuo PL; Lin LT; Lin CC
    J Pharmacol Exp Ther; 2005 Apr; 313(1):333-44. PubMed ID: 15626723
    [TBL] [Abstract][Full Text] [Related]  

  • 6. RRR-alpha-tocopheryl succinate-induced apoptosis of human breast cancer cells involves Bax translocation to mitochondria.
    Yu W; Sanders BG; Kline K
    Cancer Res; 2003 May; 63(10):2483-91. PubMed ID: 12750270
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Plumbagin (5-hydroxy-2-methyl-1,4-naphthoquinone) induces apoptosis and cell cycle arrest in A549 cells through p53 accumulation via c-Jun NH2-terminal kinase-mediated phosphorylation at serine 15 in vitro and in vivo.
    Hsu YL; Cho CY; Kuo PL; Huang YT; Lin CC
    J Pharmacol Exp Ther; 2006 Aug; 318(2):484-94. PubMed ID: 16632641
    [TBL] [Abstract][Full Text] [Related]  

  • 8. DNA and non-DNA targets in the mechanism of action of the antitumor drug trabectedin.
    David-Cordonnier MH; Gajate C; Olmea O; Laine W; de la Iglesia-Vicente J; Perez C; Cuevas C; Otero G; Manzanares I; Bailly C; Mollinedo F
    Chem Biol; 2005 Nov; 12(11):1201-10. PubMed ID: 16298299
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Acacetin-induced apoptosis of human breast cancer MCF-7 cells involves caspase cascade, mitochondria-mediated death signaling and SAPK/JNK1/2-c-Jun activation.
    Shim HY; Park JH; Paik HD; Nah SY; Kim DS; Han YS
    Mol Cells; 2007 Aug; 24(1):95-104. PubMed ID: 17846503
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Inhibition of c-Jun-N-terminal-kinase sensitizes tumor cells to CD95-induced apoptosis and induces G2/M cell cycle arrest.
    Kuntzen C; Sonuc N; De Toni EN; Opelz C; Mucha SR; Gerbes AL; Eichhorst ST
    Cancer Res; 2005 Aug; 65(15):6780-8. PubMed ID: 16061660
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Involvement of Asp-Glu-Val-Asp-directed, caspase-mediated mitogen-activated protein kinase kinase 1 Cleavage, c-Jun N-terminal kinase activation, and subsequent Bcl-2 phosphorylation for paclitaxel-induced apoptosis in HL-60 cells.
    Shiah SG; Chuang SE; Kuo ML
    Mol Pharmacol; 2001 Feb; 59(2):254-62. PubMed ID: 11160861
    [TBL] [Abstract][Full Text] [Related]  

  • 12. CD437, a synthetic retinoid, induces apoptosis in human respiratory epithelial cells via caspase-independent mitochondrial and caspase-8-dependent pathways both up-regulated by JNK signaling pathway.
    Boisvieux-Ulrich E; Sourdeval M; Marano F
    Exp Cell Res; 2005 Jul; 307(1):76-90. PubMed ID: 15922728
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Essential role of mitochondria in apoptosis of cancer cells induced by the marine alkaloid Lamellarin D.
    Ballot C; Kluza J; Martoriati A; Nyman U; Formstecher P; Joseph B; Bailly C; Marchetti P
    Mol Cancer Ther; 2009 Dec; 8(12):3307-17. PubMed ID: 19952118
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The novel antimicrotubule agent cryptophycin 52 (LY355703) induces apoptosis via multiple pathways in human prostate cancer cells.
    Drew L; Fine RL; Do TN; Douglas GP; Petrylak DP
    Clin Cancer Res; 2002 Dec; 8(12):3922-32. PubMed ID: 12473608
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Phosphorylation of Fas-associated death domain contributes to enhancement of etoposide-induced apoptosis in prostate cancer cells.
    Shimada K; Nakamura M; Ishida E; Kishi M; Yonehara S; Konishi N
    Jpn J Cancer Res; 2002 Oct; 93(10):1164-74. PubMed ID: 12417047
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Endoplasmic reticulum stress in the proapoptotic action of edelfosine in solid tumor cells.
    Nieto-Miguel T; Fonteriz RI; Vay L; Gajate C; López-Hernández S; Mollinedo F
    Cancer Res; 2007 Nov; 67(21):10368-78. PubMed ID: 17974980
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Signaling and function of caspase and c-jun N-terminal kinase in cisplatin-induced apoptosis.
    Koo MS; Kwo YG; Park JH; Choi WJ; Billiar TR; Kim YM
    Mol Cells; 2002 Apr; 13(2):194-201. PubMed ID: 12018840
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mollugin induces apoptosis in human Jurkat T cells through endoplasmic reticulum stress-mediated activation of JNK and caspase-12 and subsequent activation of mitochondria-dependent caspase cascade regulated by Bcl-xL.
    Kim SM; Park HS; Jun DY; Woo HJ; Woo MH; Yang CH; Kim YH
    Toxicol Appl Pharmacol; 2009 Dec; 241(2):210-20. PubMed ID: 19716835
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The novel triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid (CDDO) potently enhances apoptosis induced by tumor necrosis factor in human leukemia cells.
    Stadheim TA; Suh N; Ganju N; Sporn MB; Eastman A
    J Biol Chem; 2002 May; 277(19):16448-55. PubMed ID: 11880365
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mitogen-activated protein kinase/extracellular signal-regulated kinase signaling in activated T cells abrogates TRAIL-induced apoptosis upstream of the mitochondrial amplification loop and caspase-8.
    Söderström TS; Poukkula M; Holmström TH; Heiskanen KM; Eriksson JE
    J Immunol; 2002 Sep; 169(6):2851-60. PubMed ID: 12218097
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.