BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

448 related articles for article (PubMed ID: 12202832)

  • 1. Medulloblastoma growth inhibition by hedgehog pathway blockade.
    Berman DM; Karhadkar SS; Hallahan AR; Pritchard JI; Eberhart CG; Watkins DN; Chen JK; Cooper MK; Taipale J; Olson JM; Beachy PA
    Science; 2002 Aug; 297(5586):1559-61. PubMed ID: 12202832
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours.
    Berman DM; Karhadkar SS; Maitra A; Montes De Oca R; Gerstenblith MR; Briggs K; Parker AR; Shimada Y; Eshleman JR; Watkins DN; Beachy PA
    Nature; 2003 Oct; 425(6960):846-51. PubMed ID: 14520411
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Treatment of medulloblastoma with hedgehog pathway inhibitor GDC-0449.
    Rudin CM; Hann CL; Laterra J; Yauch RL; Callahan CA; Fu L; Holcomb T; Stinson J; Gould SE; Coleman B; LoRusso PM; Von Hoff DD; de Sauvage FJ; Low JA
    N Engl J Med; 2009 Sep; 361(12):1173-8. PubMed ID: 19726761
    [TBL] [Abstract][Full Text] [Related]  

  • 4. PTEN loss mitigates the response of medulloblastoma to Hedgehog pathway inhibition.
    Metcalfe C; Alicke B; Crow A; Lamoureux M; Dijkgraaf GJ; Peale F; Gould SE; de Sauvage FJ
    Cancer Res; 2013 Dec; 73(23):7034-42. PubMed ID: 24154871
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Shh pathway activity is down-regulated in cultured medulloblastoma cells: implications for preclinical studies.
    Sasai K; Romer JT; Lee Y; Finkelstein D; Fuller C; McKinnon PJ; Curran T
    Cancer Res; 2006 Apr; 66(8):4215-22. PubMed ID: 16618744
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Statins Synergize with Hedgehog Pathway Inhibitors for Treatment of Medulloblastoma.
    Gordon RE; Zhang L; Peri S; Kuo YM; Du F; Egleston BL; Ng JMY; Andrews AJ; Astsaturov I; Curran T; Yang ZJ
    Clin Cancer Res; 2018 Mar; 24(6):1375-1388. PubMed ID: 29437795
    [No Abstract]   [Full Text] [Related]  

  • 7. Two-hit model for progression of medulloblastoma preneoplasia in Patched heterozygous mice.
    Pazzaglia S; Tanori M; Mancuso M; Gessi M; Pasquali E; Leonardi S; Oliva MA; Rebessi S; Di Majo V; Covelli V; Giangaspero F; Saran A
    Oncogene; 2006 Sep; 25(40):5575-80. PubMed ID: 16636673
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Clinical implications of hedgehog signaling pathway inhibitors.
    Liu H; Gu D; Xie J
    Chin J Cancer; 2011 Jan; 30(1):13-26. PubMed ID: 21192841
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Identification of pseudolaric acid B as a novel Hedgehog pathway inhibitor in medulloblastoma.
    Wei SF; He DH; Zhang SB; Lu Y; Ye X; Fan XZ; Wang H; Wang Q; Liu YQ
    Biochem Pharmacol; 2021 Aug; 190():114593. PubMed ID: 33964282
    [TBL] [Abstract][Full Text] [Related]  

  • 10. MK-4101, a Potent Inhibitor of the Hedgehog Pathway, Is Highly Active against Medulloblastoma and Basal Cell Carcinoma.
    Filocamo G; Brunetti M; Colaceci F; Sasso R; Tanori M; Pasquali E; Alfonsi R; Mancuso M; Saran A; Lahm A; Di Marcotullio L; Steinkühler C; Pazzaglia S
    Mol Cancer Ther; 2016 Jun; 15(6):1177-89. PubMed ID: 26960983
    [TBL] [Abstract][Full Text] [Related]  

  • 11. AT-101 inhibits hedgehog pathway activity and cancer growth.
    Wang J; Peng Y; Liu Y; Yang J; Huang M; Tan W
    Cancer Chemother Pharmacol; 2015 Sep; 76(3):461-9. PubMed ID: 26113054
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A five-gene hedgehog signature developed as a patient preselection tool for hedgehog inhibitor therapy in medulloblastoma.
    Shou Y; Robinson DM; Amakye DD; Rose KL; Cho YJ; Ligon KL; Sharp T; Haider AS; Bandaru R; Ando Y; Geoerger B; Doz F; Ashley DM; Hargrave DR; Casanova M; Tawbi HA; Rodon J; Thomas AL; Mita AC; MacDonald TJ; Kieran MW
    Clin Cancer Res; 2015 Feb; 21(3):585-93. PubMed ID: 25473003
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Targeting medulloblastoma: small-molecule inhibitors of the Sonic Hedgehog pathway as potential cancer therapeutics.
    Romer J; Curran T
    Cancer Res; 2005 Jun; 65(12):4975-8. PubMed ID: 15958535
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The hedgehog pathway and neurological disorders.
    Dellovade T; Romer JT; Curran T; Rubin LL
    Annu Rev Neurosci; 2006; 29():539-63. PubMed ID: 16776596
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Canonical Notch signaling is not required for the growth of Hedgehog pathway-induced medulloblastoma.
    Julian E; Dave RK; Robson JP; Hallahan AR; Wainwright BJ
    Oncogene; 2010 Jun; 29(24):3465-76. PubMed ID: 20418906
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Suppression of the Shh pathway using a small molecule inhibitor eliminates medulloblastoma in Ptc1(+/-)p53(-/-) mice.
    Romer JT; Kimura H; Magdaleno S; Sasai K; Fuller C; Baines H; Connelly M; Stewart CF; Gould S; Rubin LL; Curran T
    Cancer Cell; 2004 Sep; 6(3):229-40. PubMed ID: 15380514
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Null mutation of DNA strand break-binding molecule poly(ADP-ribose) polymerase causes medulloblastomas in p53(-/-) mice.
    Tong WM; Ohgaki H; Huang H; Granier C; Kleihues P; Wang ZQ
    Am J Pathol; 2003 Jan; 162(1):343-52. PubMed ID: 12507917
    [TBL] [Abstract][Full Text] [Related]  

  • 18. SHH inhibitors for the treatment of medulloblastoma.
    Samkari A; White J; Packer R
    Expert Rev Neurother; 2015; 15(7):763-70. PubMed ID: 26027634
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Medulloblastoma stem cells.
    Fan X; Eberhart CG
    J Clin Oncol; 2008 Jun; 26(17):2821-7. PubMed ID: 18539960
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Hitting the target in medulloblastoma therapy.
    Bradbury J
    Drug Discov Today; 2004 Dec; 9(23):994-5. PubMed ID: 15574311
    [No Abstract]   [Full Text] [Related]  

    [Next]    [New Search]
    of 23.