BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

106 related articles for article (PubMed ID: 12207005)

  • 1. Codon 12 and codon 13 mutations at the K-ras gene induce different soft tissue sarcoma types in nude mice.
    Guerrero S; Figueras A; Casanova I; Farré L; Lloveras B; Capellà G; Trias M; Mangues R
    FASEB J; 2002 Oct; 16(12):1642-4. PubMed ID: 12207005
    [TBL] [Abstract][Full Text] [Related]  

  • 2. K-ras codon 12 mutation induces higher level of resistance to apoptosis and predisposition to anchorage-independent growth than codon 13 mutation or proto-oncogene overexpression.
    Guerrero S; Casanova I; Farré L; Mazo A; Capellà G; Mangues R
    Cancer Res; 2000 Dec; 60(23):6750-6. PubMed ID: 11118062
    [TBL] [Abstract][Full Text] [Related]  

  • 3. K-ras Asp12 mutant neither interacts with Raf, nor signals through Erk and is less tumorigenic than K-ras Val12.
    Céspedes MV; Sancho FJ; Guerrero S; Parreño M; Casanova I; Pavón MA; Marcuello E; Trias M; Cascante M; Capellà G; Mangues R
    Carcinogenesis; 2006 Nov; 27(11):2190-200. PubMed ID: 16679305
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Rit, a non-lipid-modified Ras-related protein, transforms NIH3T3 cells without activating the ERK, JNK, p38 MAPK or PI3K/Akt pathways.
    Rusyn EV; Reynolds ER; Shao H; Grana TM; Chan TO; Andres DA; Cox AD
    Oncogene; 2000 Sep; 19(41):4685-94. PubMed ID: 11032018
    [TBL] [Abstract][Full Text] [Related]  

  • 5. K-ras codon-specific mutations produce distinctive metabolic phenotypes in NIH3T3 mice [corrected] fibroblasts.
    Vizan P; Boros LG; Figueras A; Capella G; Mangues R; Bassilian S; Lim S; Lee WN; Cascante M
    Cancer Res; 2005 Jul; 65(13):5512-5. PubMed ID: 15994921
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Activation of K-ras by codon 13 mutations in C57BL/6 X C3H F1 mouse tumors induced by exposure to 1,3-butadiene.
    Goodrow T; Reynolds S; Maronpot R; Anderson M
    Cancer Res; 1990 Aug; 50(15):4818-23. PubMed ID: 2196119
    [TBL] [Abstract][Full Text] [Related]  

  • 7. p21Ras downstream effectors are increased in activity or expression in mouse liver tumors but do not differ between ras-mutated and ras-wild-type lesions.
    Kalkuhl A; Troppmair J; Buchmann A; Stinchcombe S; Buenemann CL; Rapp UR; Kaestner K; Schwarz M
    Hepatology; 1998 Apr; 27(4):1081-8. PubMed ID: 9537449
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Correlation between successful heterotransplantation of lung tumors in nude mice, poor prognosis of patients and expression of Fos, Jun, ErbB1, and Ras.
    Volm M; Mattern J
    Anticancer Res; 1993; 13(6A):2021-5. PubMed ID: 8297109
    [TBL] [Abstract][Full Text] [Related]  

  • 9. H-ras and K-ras gene mutations in primary human soft tissue sarcoma: concomitant mutations of the ras genes.
    Yoo J; Robinson RA; Lee JY
    Mod Pathol; 1999 Aug; 12(8):775-80. PubMed ID: 10463479
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Oncogenic Ras, but not (V600E)B-RAF, protects from cholesterol depletion-induced apoptosis through the PI3K/AKT pathway in colorectal cancer cells.
    Calleros L; Sánchez-Hernández I; Baquero P; Toro MJ; Chiloeches A
    Carcinogenesis; 2009 Oct; 30(10):1670-7. PubMed ID: 19700418
    [TBL] [Abstract][Full Text] [Related]  

  • 11. K-ras gene mutation enhances motility of immortalized airway cells and lung adenocarcinoma cells via Akt activation: possible contribution to non-invasive expansion of lung adenocarcinoma.
    Okudela K; Hayashi H; Ito T; Yazawa T; Suzuki T; Nakane Y; Sato H; Ishi H; KeQin X; Masuda A; Takahashi T; Kitamura H
    Am J Pathol; 2004 Jan; 164(1):91-100. PubMed ID: 14695323
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mutational and nonmutational activation of p21ras in rat colonic azoxymethane-induced tumors: effects on mitogen-activated protein kinase, cyclooxygenase-2, and cyclin D1.
    Bissonnette M; Khare S; von Lintig FC; Wali RK; Nguyen L; Zhang Y; Hart J; Skarosi S; Varki N; Boss GR; Brasitus TA
    Cancer Res; 2000 Aug; 60(16):4602-9. PubMed ID: 10969813
    [TBL] [Abstract][Full Text] [Related]  

  • 13. An overexpressed N-ras proto-oncogene cooperates with N-methylnitrosourea in mouse mammary carcinogenesis.
    Mangues R; Kahn JM; Seidman I; Pellicer A
    Cancer Res; 1994 Dec; 54(24):6395-401. PubMed ID: 7987834
    [TBL] [Abstract][Full Text] [Related]  

  • 14. p53 and Egr-1 additively suppress transformed growth in HT1080 cells but Egr-1 counteracts p53-dependent apoptosis.
    de Belle I; Huang RP; Fan Y; Liu C; Mercola D; Adamson ED
    Oncogene; 1999 Jun; 18(24):3633-42. PubMed ID: 10380885
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Stepwise neoplastic transformation of a telomerase immortalized fibroblast cell line.
    Zongaro S; de Stanchina E; Colombo T; D'Incalci M; Giulotto E; Mondello C
    Cancer Res; 2005 Dec; 65(24):11411-8. PubMed ID: 16357149
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Regulation of epidermal growth factor receptor by activated H-ras and V-myc oncogenes in mouse Balb/3T3 cells: possible roles of AP-1.
    Okimoto T; Kohno K; Kuwano M; Gopas J; Kung HF; Ono M
    Oncogene; 1996 Apr; 12(8):1625-33. PubMed ID: 8622882
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Generation of stable CD4+ and CD8+ T cell lines from patients immunized with ras oncogene-derived peptides reflecting codon 12 mutations.
    Abrams SI; Khleif SN; Bergmann-Leitner ES; Kantor JA; Chung Y; Hamilton JM; Schlom J
    Cell Immunol; 1997 Dec; 182(2):137-51. PubMed ID: 9514698
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Extracellular matrix regulates glomerular epithelial cell survival and proliferation.
    Bijian K; Takano T; Papillon J; Khadir A; Cybulsky AV
    Am J Physiol Renal Physiol; 2004 Feb; 286(2):F255-66. PubMed ID: 14559718
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Activation of the K-ras oncogene in colorectal neoplasms is associated with decreased apoptosis.
    Ward RL; Todd AV; Santiago F; O'Connor T; Hawkins NJ
    Cancer; 1997 Mar; 79(6):1106-13. PubMed ID: 9070487
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Resistance to chemotherapy via Stat3-dependent overexpression of Bcl-2 in metastatic breast cancer cells.
    Real PJ; Sierra A; De Juan A; Segovia JC; Lopez-Vega JM; Fernandez-Luna JL
    Oncogene; 2002 Oct; 21(50):7611-8. PubMed ID: 12400004
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.