BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

452 related articles for article (PubMed ID: 12209150)

  • 1. Protein tyrosine phosphatase 1B inhibitors for diabetes.
    Johnson TO; Ermolieff J; Jirousek MR
    Nat Rev Drug Discov; 2002 Sep; 1(9):696-709. PubMed ID: 12209150
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Protein tyrosine phosphatase 1B as a target for the treatment of impaired glucose tolerance and type II diabetes.
    Liu G; Trevillyan JM
    Curr Opin Investig Drugs; 2002 Nov; 3(11):1608-16. PubMed ID: 12476961
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Novel protein tyrosine phosphatase 1B inhibitors: interaction requirements for improved intracellular efficacy in type 2 diabetes mellitus and obesity control.
    Popov D
    Biochem Biophys Res Commun; 2011 Jul; 410(3):377-81. PubMed ID: 21683066
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Protein tyrosine phosphatase 1B inhibitors for the treatment of type 2 diabetes and obesity: recent advances.
    Harley EA; Levens N
    Curr Opin Investig Drugs; 2003 Oct; 4(10):1179-89. PubMed ID: 14649209
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inhibition of the protein tyrosine phosphatase PTP1B: potential therapy for obesity, insulin resistance and type-2 diabetes mellitus.
    Koren S; Fantus IG
    Best Pract Res Clin Endocrinol Metab; 2007 Dec; 21(4):621-40. PubMed ID: 18054739
    [TBL] [Abstract][Full Text] [Related]  

  • 6. In silico structure-based design of a potent and selective small peptide inhibitor of protein tyrosine phosphatase 1B, a novel therapeutic target for obesity and type 2 diabetes mellitus: a computer modeling approach.
    Rao GS; Ramachandran MV; Bajaj JS
    J Biomol Struct Dyn; 2006 Feb; 23(4):377-84. PubMed ID: 16363874
    [TBL] [Abstract][Full Text] [Related]  

  • 7. PTP1B as a drug target: recent developments in PTP1B inhibitor discovery.
    Zhang S; Zhang ZY
    Drug Discov Today; 2007 May; 12(9-10):373-81. PubMed ID: 17467573
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Dammaranes from Gynostemma pentaphyllum and synthesis of their derivatives as inhibitors of protein tyrosine phosphatase 1B.
    Xu JQ; Shen Q; Li J; Hu LH
    Bioorg Med Chem; 2010 Jun; 18(11):3934-9. PubMed ID: 20472439
    [TBL] [Abstract][Full Text] [Related]  

  • 9. [Does inhibition of tyrosine phosphatase 1B protect from obesity and type 2 diabetes?].
    Ukkola O; Santaniemi M
    Duodecim; 2002; 118(18):1857-62. PubMed ID: 12422667
    [No Abstract]   [Full Text] [Related]  

  • 10. Recent advances in the development of small molecule inhibitors of PTP1B for the treatment of insulin resistance and type 2 diabetes.
    Tobin JF; Tam S
    Curr Opin Drug Discov Devel; 2002 Jul; 5(4):500-12. PubMed ID: 12197308
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structure-based optimization of benzoic acids as inhibitors of protein tyrosine phosphatase 1B and low molecular weight protein tyrosine phosphatase.
    Maccari R; Ottanà R; Ciurleo R; Paoli P; Manao G; Camici G; Laggner C; Langer T
    ChemMedChem; 2009 Jun; 4(6):957-62. PubMed ID: 19288492
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis of functionalized acetophenones as protein tyrosine phosphatase 1B inhibitors.
    Dixit M; Tripathi BK; Srivastava AK; Goel A
    Bioorg Med Chem Lett; 2005 Jul; 15(14):3394-7. PubMed ID: 15951172
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Targeting protein tyrosine phosphatase to enhance insulin action for the potential treatment of diabetes.
    Kasibhatla B; Wos J; Peters KG
    Curr Opin Investig Drugs; 2007 Oct; 8(10):805-13. PubMed ID: 17907056
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis, activity and molecular modeling of a new series of chromones as low molecular weight protein tyrosine phosphatase inhibitors.
    Forghieri M; Laggner C; Paoli P; Langer T; Manao G; Camici G; Bondioli L; Prati F; Costantino L
    Bioorg Med Chem; 2009 Apr; 17(7):2658-72. PubMed ID: 19297174
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Prodrug delivery of novel PTP1B inhibitors to enhance insulin signalling.
    Erbe DV; Klaman LD; Wilson DP; Wan ZK; Kirincich SJ; Will S; Xu X; Kung L; Wang S; Tam S; Lee J; Tobin JF
    Diabetes Obes Metab; 2009 Jun; 11(6):579-88. PubMed ID: 19383031
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis and biological evaluation of 4,4-dimethyl lithocholic acid derivatives as novel inhibitors of protein tyrosine phosphatase 1B.
    He HB; Gao LX; Deng QF; Ma WP; Tang CL; Qiu WW; Tang J; Li JY; Li J; Yang F
    Bioorg Med Chem Lett; 2012 Dec; 22(23):7237-42. PubMed ID: 23067554
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Protein-tyrosine phosphatase 1B (PTP1B): a novel therapeutic target for type 2 diabetes mellitus, obesity and related states of insulin resistance.
    Goldstein BJ
    Curr Drug Targets Immune Endocr Metabol Disord; 2001 Nov; 1(3):265-75. PubMed ID: 12477292
    [TBL] [Abstract][Full Text] [Related]  

  • 18. PTP1B inhibitors as potential therapeutics in the treatment of type 2 diabetes and obesity.
    Zhang ZY; Lee SY
    Expert Opin Investig Drugs; 2003 Feb; 12(2):223-33. PubMed ID: 12556216
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Inhibition of protein tyrosine phosphatase 1B by ursane-type triterpenes isolated from Symplocos paniculata.
    Na M; Yang S; He L; Oh H; Kim BS; Oh WK; Kim BY; Ahn JS
    Planta Med; 2006 Feb; 72(3):261-3. PubMed ID: 16534732
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Establishment of a cell-based drug screening model for identifying down-regulators of Protein Tyrosine Phosphatase 1B expression.
    Lian JH; Guo L; Hu WR; Wu GL; Ji W; Gong BQ
    Exp Clin Endocrinol Diabetes; 2007 Jan; 115(1):24-8. PubMed ID: 17286230
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 23.