452 related articles for article (PubMed ID: 12209150)
1. Protein tyrosine phosphatase 1B inhibitors for diabetes.
Johnson TO; Ermolieff J; Jirousek MR
Nat Rev Drug Discov; 2002 Sep; 1(9):696-709. PubMed ID: 12209150
[TBL] [Abstract][Full Text] [Related]
2. Protein tyrosine phosphatase 1B as a target for the treatment of impaired glucose tolerance and type II diabetes.
Liu G; Trevillyan JM
Curr Opin Investig Drugs; 2002 Nov; 3(11):1608-16. PubMed ID: 12476961
[TBL] [Abstract][Full Text] [Related]
3. Novel protein tyrosine phosphatase 1B inhibitors: interaction requirements for improved intracellular efficacy in type 2 diabetes mellitus and obesity control.
Popov D
Biochem Biophys Res Commun; 2011 Jul; 410(3):377-81. PubMed ID: 21683066
[TBL] [Abstract][Full Text] [Related]
4. Protein tyrosine phosphatase 1B inhibitors for the treatment of type 2 diabetes and obesity: recent advances.
Harley EA; Levens N
Curr Opin Investig Drugs; 2003 Oct; 4(10):1179-89. PubMed ID: 14649209
[TBL] [Abstract][Full Text] [Related]
5. Inhibition of the protein tyrosine phosphatase PTP1B: potential therapy for obesity, insulin resistance and type-2 diabetes mellitus.
Koren S; Fantus IG
Best Pract Res Clin Endocrinol Metab; 2007 Dec; 21(4):621-40. PubMed ID: 18054739
[TBL] [Abstract][Full Text] [Related]
6. In silico structure-based design of a potent and selective small peptide inhibitor of protein tyrosine phosphatase 1B, a novel therapeutic target for obesity and type 2 diabetes mellitus: a computer modeling approach.
Rao GS; Ramachandran MV; Bajaj JS
J Biomol Struct Dyn; 2006 Feb; 23(4):377-84. PubMed ID: 16363874
[TBL] [Abstract][Full Text] [Related]
7. PTP1B as a drug target: recent developments in PTP1B inhibitor discovery.
Zhang S; Zhang ZY
Drug Discov Today; 2007 May; 12(9-10):373-81. PubMed ID: 17467573
[TBL] [Abstract][Full Text] [Related]
8. Dammaranes from Gynostemma pentaphyllum and synthesis of their derivatives as inhibitors of protein tyrosine phosphatase 1B.
Xu JQ; Shen Q; Li J; Hu LH
Bioorg Med Chem; 2010 Jun; 18(11):3934-9. PubMed ID: 20472439
[TBL] [Abstract][Full Text] [Related]
9. [Does inhibition of tyrosine phosphatase 1B protect from obesity and type 2 diabetes?].
Ukkola O; Santaniemi M
Duodecim; 2002; 118(18):1857-62. PubMed ID: 12422667
[No Abstract] [Full Text] [Related]
10. Recent advances in the development of small molecule inhibitors of PTP1B for the treatment of insulin resistance and type 2 diabetes.
Tobin JF; Tam S
Curr Opin Drug Discov Devel; 2002 Jul; 5(4):500-12. PubMed ID: 12197308
[TBL] [Abstract][Full Text] [Related]
11. Structure-based optimization of benzoic acids as inhibitors of protein tyrosine phosphatase 1B and low molecular weight protein tyrosine phosphatase.
Maccari R; Ottanà R; Ciurleo R; Paoli P; Manao G; Camici G; Laggner C; Langer T
ChemMedChem; 2009 Jun; 4(6):957-62. PubMed ID: 19288492
[TBL] [Abstract][Full Text] [Related]
12. Synthesis of functionalized acetophenones as protein tyrosine phosphatase 1B inhibitors.
Dixit M; Tripathi BK; Srivastava AK; Goel A
Bioorg Med Chem Lett; 2005 Jul; 15(14):3394-7. PubMed ID: 15951172
[TBL] [Abstract][Full Text] [Related]
13. Targeting protein tyrosine phosphatase to enhance insulin action for the potential treatment of diabetes.
Kasibhatla B; Wos J; Peters KG
Curr Opin Investig Drugs; 2007 Oct; 8(10):805-13. PubMed ID: 17907056
[TBL] [Abstract][Full Text] [Related]
14. Synthesis, activity and molecular modeling of a new series of chromones as low molecular weight protein tyrosine phosphatase inhibitors.
Forghieri M; Laggner C; Paoli P; Langer T; Manao G; Camici G; Bondioli L; Prati F; Costantino L
Bioorg Med Chem; 2009 Apr; 17(7):2658-72. PubMed ID: 19297174
[TBL] [Abstract][Full Text] [Related]
15. Prodrug delivery of novel PTP1B inhibitors to enhance insulin signalling.
Erbe DV; Klaman LD; Wilson DP; Wan ZK; Kirincich SJ; Will S; Xu X; Kung L; Wang S; Tam S; Lee J; Tobin JF
Diabetes Obes Metab; 2009 Jun; 11(6):579-88. PubMed ID: 19383031
[TBL] [Abstract][Full Text] [Related]
16. Synthesis and biological evaluation of 4,4-dimethyl lithocholic acid derivatives as novel inhibitors of protein tyrosine phosphatase 1B.
He HB; Gao LX; Deng QF; Ma WP; Tang CL; Qiu WW; Tang J; Li JY; Li J; Yang F
Bioorg Med Chem Lett; 2012 Dec; 22(23):7237-42. PubMed ID: 23067554
[TBL] [Abstract][Full Text] [Related]
17. Protein-tyrosine phosphatase 1B (PTP1B): a novel therapeutic target for type 2 diabetes mellitus, obesity and related states of insulin resistance.
Goldstein BJ
Curr Drug Targets Immune Endocr Metabol Disord; 2001 Nov; 1(3):265-75. PubMed ID: 12477292
[TBL] [Abstract][Full Text] [Related]
18. PTP1B inhibitors as potential therapeutics in the treatment of type 2 diabetes and obesity.
Zhang ZY; Lee SY
Expert Opin Investig Drugs; 2003 Feb; 12(2):223-33. PubMed ID: 12556216
[TBL] [Abstract][Full Text] [Related]
19. Inhibition of protein tyrosine phosphatase 1B by ursane-type triterpenes isolated from Symplocos paniculata.
Na M; Yang S; He L; Oh H; Kim BS; Oh WK; Kim BY; Ahn JS
Planta Med; 2006 Feb; 72(3):261-3. PubMed ID: 16534732
[TBL] [Abstract][Full Text] [Related]
20. Establishment of a cell-based drug screening model for identifying down-regulators of Protein Tyrosine Phosphatase 1B expression.
Lian JH; Guo L; Hu WR; Wu GL; Ji W; Gong BQ
Exp Clin Endocrinol Diabetes; 2007 Jan; 115(1):24-8. PubMed ID: 17286230
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]