BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

182 related articles for article (PubMed ID: 12213053)

  • 1. Mazindol analogues as potential inhibitors of the cocaine binding site at the dopamine transporter.
    Houlihan WJ; Kelly L; Pankuch J; Koletar J; Brand L; Janowsky A; Kopajtic TA
    J Med Chem; 2002 Sep; 45(19):4097-109. PubMed ID: 12213053
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Benzo- and cyclohexanomazindol analogues as potential inhibitors of the cocaine binding site at the dopamine transporter.
    Houlihan WJ; Ahmad UF; Koletar J; Kelly L; Brand L; Kopajtic TA
    J Med Chem; 2002 Sep; 45(19):4110-8. PubMed ID: 12213054
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Halogenated mazindol analogs as potential inhibitors of the cocaine binding site at the dopamine transporter.
    Houlihan WJ; Boja JW; Parrino VA; Kopajtic TA; Kuhar MJ
    J Med Chem; 1996 Dec; 39(25):4935-41. PubMed ID: 8960553
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Novel tropane-based irreversible ligands for the dopamine transporter.
    Zou MF; Kopajtic T; Katz JL; Wirtz S; Justice JB; Newman AH
    J Med Chem; 2001 Dec; 44(25):4453-61. PubMed ID: 11728190
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis and pharmacology of site specific cocaine abuse treatment agents: 8-substituted isotropane (3-azabicyclo[3.2.1]octane) dopamine uptake inhibitors.
    Kim DI; Schweri MM; Deutsch HM
    J Med Chem; 2003 Apr; 46(8):1456-64. PubMed ID: 12672245
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Three-dimensional quantitative structure-activity relationships of mazindol analogues at the dopamine transporter.
    Kulkarni SS; Newman AH; Houlihan WJ
    J Med Chem; 2002 Sep; 45(19):4119-27. PubMed ID: 12213055
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Discovery of substituted 3,4-diphenyl-thiazoles as a novel class of monoamine transporter inhibitors through 3-D pharmacophore search using a new pharmacophore model derived from mazindol.
    Enyedy IJ; Wang J; Zaman WA; Johnson KM; Wang S
    Bioorg Med Chem Lett; 2002 Jul; 12(13):1775-8. PubMed ID: 12067559
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Studies of the biogenic amine transporters. VIII: identification of a novel partial inhibitor of dopamine uptake and dopamine transporter binding.
    Rothman RB; Dersch CM; Carroll FI; Ananthan S
    Synapse; 2002 Mar; 43(4):268-74. PubMed ID: 11835522
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Tolerance in the replacement of the benzhydrylic O atom in 4-[2-(diphenylmethoxy)ethyl]-1-benzylpiperidine derivatives by an N atom: development of new-generation potent and selective N-analogue molecules for the dopamine transporter.
    Dutta AK; Xu C; Reith ME
    J Med Chem; 1998 Aug; 41(17):3293-7. PubMed ID: 9703474
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Differential sensitivity to NaCl for inhibitors and substrates that recognize mutually exclusive binding sites on the neuronal transporter of dopamine in rat striatal membranes.
    Tidjane Corera A; Do-RĂ©go JC; Costentin J; Bonnet JJ
    Neurosci Res; 2001 Mar; 39(3):319-25. PubMed ID: 11248372
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis and pharmacology of site-specific cocaine abuse treatment agents: 2-substituted-6-amino-5-phenylbicyclo[2.2.2]octanes.
    Javanmard S; Deutsch HM; Collard DM; Kuhar MJ; Schweri MM
    J Med Chem; 1999 Nov; 42(23):4836-43. PubMed ID: 10579846
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structure-activity relationship studies of 4-[2-(diphenylmethoxy)ethyl]-1-benzylpiperidine derivatives and their N-analogues: evaluation of O-and N-analogues and their binding to monoamine transporters.
    Dutta AK; Fei XS; Beardsley PM; Newman JL; Reith ME
    J Med Chem; 2001 Mar; 44(6):937-48. PubMed ID: 11300876
    [TBL] [Abstract][Full Text] [Related]  

  • 13. 2'-substituted analogs of cocaine: synthesis and dopamine transporter binding potencies.
    el-Moselhy TF; Avor KS; Basmadjian GP
    Arch Pharm (Weinheim); 2001 Sep; 334(8-9):275-8. PubMed ID: 11688137
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis and biological evaluation of meperidine analogues at monoamine transporters.
    Lomenzo SA; Rhoden JB; Izenwasser S; Wade D; Kopajtic T; Katz JL; Trudell ML
    J Med Chem; 2005 Mar; 48(5):1336-43. PubMed ID: 15743177
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structure-activity relationship studies of highly selective inhibitors of the dopamine transporter: N-benzylpiperidine analogues of 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine.
    Greiner E; Prisinzano T; Johnson EM; Dersch CM; Marcus J; Partilla JS; Rothman RB; Jacobson AE; Rice KC
    J Med Chem; 2003 Apr; 46(8):1465-9. PubMed ID: 12672246
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Assessment of mazindane, a pro-drug form of mazindol, in assays used to define cocaine treatment agents.
    Houlihan WJ; Kelly L
    Eur J Pharmacol; 2003 Jan; 458(3):263-73. PubMed ID: 12504782
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Identification of a novel partial inhibitor of dopamine transporter among 4-substituted 2-phenylquinazolines.
    Ananthan S; Saini SK; Khare R; Clayton SD; Dersch CM; Rothman RB
    Bioorg Med Chem Lett; 2002 Aug; 12(16):2225-8. PubMed ID: 12127543
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis and transporter binding properties of bridged piperazine analogues of 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine (GBR 12909).
    Zhang Y; Rothman RB; Dersch CM; de Costa BR; Jacobson AE; Rice KC
    J Med Chem; 2000 Dec; 43(25):4840-9. PubMed ID: 11123994
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Relationships between the catechol substrate binding site and amphetamine, cocaine, and mazindol binding sites in a kinetic model of the striatal transporter of dopamine in vitro.
    Wayment H; Meiergerd SM; Schenk JO
    J Neurochem; 1998 May; 70(5):1941-9. PubMed ID: 9572278
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and preliminary characterization of a high-affinity novel radioligand for the dopamine transporter.
    Dutta AK; Reith ME; Madras BK
    Synapse; 2001 Feb; 39(2):175-81. PubMed ID: 11180505
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.