BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

245 related articles for article (PubMed ID: 12217388)

  • 1. Protein tyrosine kinase Syk in mast cell signaling.
    Siraganian RP; Zhang J; Suzuki K; Sada K
    Mol Immunol; 2002 Sep; 38(16-18):1229-33. PubMed ID: 12217388
    [TBL] [Abstract][Full Text] [Related]  

  • 2. CD45 is essential for Fc epsilon RI signaling by ZAP70, but not Syk, in Syk-negative mast cells.
    Zhang J; Siraganian RP
    J Immunol; 1999 Sep; 163(5):2508-16. PubMed ID: 10452987
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Phosphorylation of Tyr342 in the linker region of Syk is critical for Fc epsilon RI signaling in mast cells.
    Zhang J; Berenstein E; Siraganian RP
    Mol Cell Biol; 2002 Dec; 22(23):8144-54. PubMed ID: 12417718
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Downstream signaling molecules bind to different phosphorylated immunoreceptor tyrosine-based activation motif (ITAM) peptides of the high affinity IgE receptor.
    Kimura T; Kihara H; Bhattacharyya S; Sakamoto H; Appella E; Siraganian RP
    J Biol Chem; 1996 Nov; 271(44):27962-8. PubMed ID: 8910399
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Distinct roles for the linker region tyrosines of Syk in FcepsilonRI signaling in primary mast cells.
    Simon M; Vanes L; Geahlen RL; Tybulewicz VL
    J Biol Chem; 2005 Feb; 280(6):4510-7. PubMed ID: 15576379
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The protein tyrosine kinase syk activity is reduced by clustering the mast cell function-associated antigen.
    Xu R; Pecht I
    Eur J Immunol; 2001 May; 31(5):1571-81. PubMed ID: 11465115
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Solution structure of the C-terminal SH2 domain of the human tyrosine kinase Syk complexed with a phosphotyrosine pentapeptide.
    Narula SS; Yuan RW; Adams SE; Green OM; Green J; Philips TB; Zydowsky LD; Botfield MC; Hatada M; Laird ER
    Structure; 1995 Oct; 3(10):1061-73. PubMed ID: 8590001
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Protein tyrosine kinases Syk and ZAP-70 display distinct requirements for Src family kinases in immune response receptor signal transduction.
    Zoller KE; MacNeil IA; Brugge JS
    J Immunol; 1997 Feb; 158(4):1650-9. PubMed ID: 9029101
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Critical role for the tyrosine kinase Syk in signalling through the high affinity IgE receptor of mast cells.
    Costello PS; Turner M; Walters AE; Cunningham CN; Bauer PH; Downward J; Tybulewicz VL
    Oncogene; 1996 Dec; 13(12):2595-605. PubMed ID: 9000133
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structure and function of Syk protein-tyrosine kinase.
    Sada K; Takano T; Yanagi S; Yamamura H
    J Biochem; 2001 Aug; 130(2):177-86. PubMed ID: 11481033
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Fc epsilon receptor I-associated lyn-dependent phosphorylation of Fc gamma receptor IIB during negative regulation of mast cell activation.
    Malbec O; Fong DC; Turner M; Tybulewicz VL; Cambier JC; Fridman WH; Daëron M
    J Immunol; 1998 Feb; 160(4):1647-58. PubMed ID: 9469421
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mutations in the activation loop tyrosines of protein tyrosine kinase Syk abrogate intracellular signaling but not kinase activity.
    Zhang J; Kimura T; Siraganian RP
    J Immunol; 1998 Oct; 161(8):4366-74. PubMed ID: 9780214
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A unique insert in the linker domain of Syk is necessary for its function in immunoreceptor signalling.
    Latour S; Zhang J; Siraganian RP; Veillette A
    EMBO J; 1998 May; 17(9):2584-95. PubMed ID: 9564041
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Regulation of rat basophilic leukemia-2H3 mast cell secretion by a constitutive Lyn kinase interaction with the high affinity IgE receptor (Fc epsilon RI).
    Vonakis BM; Gibbons SP; Rotté MJ; Brothers EA; Kim SC; Chichester K; MacDonald SM
    J Immunol; 2005 Oct; 175(7):4543-54. PubMed ID: 16177098
    [TBL] [Abstract][Full Text] [Related]  

  • 15. ER-27319, an acridone-related compound, inhibits release of antigen-induced allergic mediators from mast cells by selective inhibition of fcepsilon receptor I-mediated activation of Syk.
    Moriya K; Rivera J; Odom S; Sakuma Y; Muramato K; Yoshiuchi T; Miyamoto M; Yamada K
    Proc Natl Acad Sci U S A; 1997 Nov; 94(23):12539-44. PubMed ID: 9356485
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Transfection of Syk protein tyrosine kinase reconstitutes high affinity IgE receptor-mediated degranulation in a Syk-negative variant of rat basophilic leukemia RBL-2H3 cells.
    Zhang J; Berenstein EH; Evans RL; Siraganian RP
    J Exp Med; 1996 Jul; 184(1):71-9. PubMed ID: 8691151
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Differential expression of ZAP-70 and Syk protein tyrosine kinases, and the role of this family of protein tyrosine kinases in TCR signaling.
    Chan AC; van Oers NS; Tran A; Turka L; Law CL; Ryan JC; Clark EA; Weiss A
    J Immunol; 1994 May; 152(10):4758-66. PubMed ID: 8176201
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Direct interaction of Syk and Lyn protein tyrosine kinases in rat basophilic leukemia cells activated via type I Fc epsilon receptors.
    Amoui M; Dráberová L; Tolar P; Dráber P
    Eur J Immunol; 1997 Jan; 27(1):321-8. PubMed ID: 9022035
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Zeta-associated protein of 70 kDa (ZAP-70), but not Syk, tyrosine kinase can mediate apoptosis of T cells through the Fas/Fas ligand, caspase-8 and caspase-3 pathways.
    Zhong L; Wu CH; Lee WH; Liu CP
    J Immunol; 2004 Feb; 172(3):1472-82. PubMed ID: 14734724
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Once phosphorylated, tyrosines in carboxyl terminus of protein-tyrosine kinase Syk interact with signaling proteins, including TULA-2, a negative regulator of mast cell degranulation.
    de Castro RO; Zhang J; Groves JR; Barbu EA; Siraganian RP
    J Biol Chem; 2012 Mar; 287(11):8194-204. PubMed ID: 22267732
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.