310 related articles for article (PubMed ID: 12217689)
1. The RUNX1 Runt domain at 1.25A resolution: a structural switch and specifically bound chloride ions modulate DNA binding.
Bäckström S; Wolf-Watz M; Grundström C; Härd T; Grundström T; Sauer UH
J Mol Biol; 2002 Sep; 322(2):259-72. PubMed ID: 12217689
[TBL] [Abstract][Full Text] [Related]
2. Structural analyses of DNA recognition by the AML1/Runx-1 Runt domain and its allosteric control by CBFbeta.
Tahirov TH; Inoue-Bungo T; Morii H; Fujikawa A; Sasaki M; Kimura K; Shiina M; Sato K; Kumasaka T; Yamamoto M; Ishii S; Ogata K
Cell; 2001 Mar; 104(5):755-67. PubMed ID: 11257229
[TBL] [Abstract][Full Text] [Related]
3. Chloride binding by the AML1/Runx1 transcription factor studied by NMR.
Wolf-Watz M; Bäckström S; Grundström T; Sauer U; Härd T
FEBS Lett; 2001 Jan; 488(1-2):81-4. PubMed ID: 11163800
[TBL] [Abstract][Full Text] [Related]
4. Functional mutagenesis of AML1/RUNX1 and PEBP2 beta/CBF beta define distinct, non-overlapping sites for DNA recognition and heterodimerization by the Runt domain.
Nagata T; Werner MH
J Mol Biol; 2001 Apr; 308(2):191-203. PubMed ID: 11327761
[TBL] [Abstract][Full Text] [Related]
5. Structural basis for the heterodimeric interaction between the acute leukaemia-associated transcription factors AML1 and CBFbeta.
Warren AJ; Bravo J; Williams RL; Rabbitts TH
EMBO J; 2000 Jun; 19(12):3004-15. PubMed ID: 10856244
[TBL] [Abstract][Full Text] [Related]
6. CBFbeta allosterically regulates the Runx1 Runt domain via a dynamic conformational equilibrium.
Yan J; Liu Y; Lukasik SM; Speck NA; Bushweller JH
Nat Struct Mol Biol; 2004 Sep; 11(9):901-6. PubMed ID: 15322525
[TBL] [Abstract][Full Text] [Related]
7. Structure and backbone dynamics of Apo-CBFbeta in solution.
Wolf-Watz M; Grundström T; Härd T
Biochemistry; 2001 Sep; 40(38):11423-32. PubMed ID: 11560490
[TBL] [Abstract][Full Text] [Related]
8. The leukemia-associated AML1 (Runx1)--CBF beta complex functions as a DNA-induced molecular clamp.
Bravo J; Li Z; Speck NA; Warren AJ
Nat Struct Biol; 2001 Apr; 8(4):371-8. PubMed ID: 11276260
[TBL] [Abstract][Full Text] [Related]
9. DNA recognition by the RUNX1 transcription factor is mediated by an allosteric transition in the RUNT domain and by DNA bending.
Bartfeld D; Shimon L; Couture GC; Rabinovich D; Frolow F; Levanon D; Groner Y; Shakked Z
Structure; 2002 Oct; 10(10):1395-407. PubMed ID: 12377125
[TBL] [Abstract][Full Text] [Related]
10. Energetic and functional contribution of residues in the core binding factor beta (CBFbeta ) subunit to heterodimerization with CBFalpha.
Tang YY; Shi J; Zhang L; Davis A; Bravo J; Warren AJ; Speck NA; Bushweller JH
J Biol Chem; 2000 Dec; 275(50):39579-88. PubMed ID: 10984496
[TBL] [Abstract][Full Text] [Related]
11. Auto-inhibition and partner proteins, core-binding factor beta (CBFbeta) and Ets-1, modulate DNA binding by CBFalpha2 (AML1).
Gu TL; Goetz TL; Graves BJ; Speck NA
Mol Cell Biol; 2000 Jan; 20(1):91-103. PubMed ID: 10594012
[TBL] [Abstract][Full Text] [Related]
12. Mutagenesis of the Runt domain defines two energetic hot spots for heterodimerization with the core binding factor beta subunit.
Zhang L; Li Z; Yan J; Pradhan P; Corpora T; Cheney MD; Bravo J; Warren AJ; Bushweller JH; Speck NA
J Biol Chem; 2003 Aug; 278(35):33097-104. PubMed ID: 12807883
[TBL] [Abstract][Full Text] [Related]
13. The Ig fold of the core binding factor alpha Runt domain is a member of a family of structurally and functionally related Ig-fold DNA-binding domains.
Berardi MJ; Sun C; Zehr M; Abildgaard F; Peng J; Speck NA; Bushweller JH
Structure; 1999 Oct; 7(10):1247-56. PubMed ID: 10545320
[TBL] [Abstract][Full Text] [Related]
14. Crystallization and preliminary studies of the DNA-binding runt domain of AML1.
Bäckström S; Huang SH; Wolf-Watz M; Xie XQ; Härd T; Grundström T; Sauer UH
Acta Crystallogr D Biol Crystallogr; 2001 Feb; 57(Pt 2):269-71. PubMed ID: 11173476
[TBL] [Abstract][Full Text] [Related]
15. Solution properties of the free and DNA-bound Runt domain of AML1.
Wolf-Watz M; Xie XQ; Holm M; Grundström T; Härd T
Eur J Biochem; 1999 Apr; 261(1):251-60. PubMed ID: 10103057
[TBL] [Abstract][Full Text] [Related]
16. Dimerization with PEBP2beta protects RUNX1/AML1 from ubiquitin-proteasome-mediated degradation.
Huang G; Shigesada K; Ito K; Wee HJ; Yokomizo T; Ito Y
EMBO J; 2001 Feb; 20(4):723-33. PubMed ID: 11179217
[TBL] [Abstract][Full Text] [Related]
17. Core-binding factor beta interacts with Runx2 and is required for skeletal development.
Yoshida CA; Furuichi T; Fujita T; Fukuyama R; Kanatani N; Kobayashi S; Satake M; Takada K; Komori T
Nat Genet; 2002 Dec; 32(4):633-8. PubMed ID: 12434152
[TBL] [Abstract][Full Text] [Related]
18. Molecular basis for a dominant inactivation of RUNX1/AML1 by the leukemogenic inversion 16 chimera.
Huang G; Shigesada K; Wee HJ; Liu PP; Osato M; Ito Y
Blood; 2004 Apr; 103(8):3200-7. PubMed ID: 15070703
[TBL] [Abstract][Full Text] [Related]
19. Frequent downregulation of the runt domain transcription factors RUNX1, RUNX3 and their cofactor CBFB in gastric cancer.
Sakakura C; Hagiwara A; Miyagawa K; Nakashima S; Yoshikawa T; Kin S; Nakase Y; Ito K; Yamagishi H; Yazumi S; Chiba T; Ito Y
Int J Cancer; 2005 Jan; 113(2):221-8. PubMed ID: 15386419
[TBL] [Abstract][Full Text] [Related]
20. Cooperative binding of DNA and CBFbeta to the Runt domain of the CBFalpha studied via MD simulations.
Habtemariam B; Anisimov VM; MacKerell AD
Nucleic Acids Res; 2005; 33(13):4212-22. PubMed ID: 16049027
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
