BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

313 related articles for article (PubMed ID: 12217903)

  • 1. Insulin signaling during perinatal liver development in the rat.
    Anand P; Boylan JM; Ou Y; Gruppuso PA
    Am J Physiol Endocrinol Metab; 2002 Oct; 283(4):E844-52. PubMed ID: 12217903
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mammalian target of rapamycin pathway regulates insulin signaling via subcellular redistribution of insulin receptor substrate 1 and integrates nutritional signals and metabolic signals of insulin.
    Takano A; Usui I; Haruta T; Kawahara J; Uno T; Iwata M; Kobayashi M
    Mol Cell Biol; 2001 Aug; 21(15):5050-62. PubMed ID: 11438661
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Endotoxin disrupts the leucine-signaling pathway involving phosphorylation of mTOR, 4E-BP1, and S6K1 in skeletal muscle.
    Lang CH; Frost RA
    J Cell Physiol; 2005 Apr; 203(1):144-55. PubMed ID: 15389631
    [TBL] [Abstract][Full Text] [Related]  

  • 4. IGF-I and insulin regulate eIF4F formation by different mechanisms in muscle and liver in the ovine fetus.
    Shen W; Mallon D; Boyle DW; Liechty EA
    Am J Physiol Endocrinol Metab; 2002 Sep; 283(3):E593-603. PubMed ID: 12169454
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Increased activation of the mammalian target of rapamycin pathway in liver and skeletal muscle of obese rats: possible involvement in obesity-linked insulin resistance.
    Khamzina L; Veilleux A; Bergeron S; Marette A
    Endocrinology; 2005 Mar; 146(3):1473-81. PubMed ID: 15604215
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Role of phospholipase D1 in the regulation of mTOR activity by lysophosphatidic acid.
    Kam Y; Exton JH
    FASEB J; 2004 Feb; 18(2):311-9. PubMed ID: 14769825
    [TBL] [Abstract][Full Text] [Related]  

  • 7. PI3K-FRAP/mTOR pathway is critical for hepatocyte proliferation whereas MEK/ERK supports both proliferation and survival.
    Coutant A; Rescan C; Gilot D; Loyer P; Guguen-Guillouzo C; Baffet G
    Hepatology; 2002 Nov; 36(5):1079-88. PubMed ID: 12395317
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Overexpressed eIF4E is functionally active in surgical margins of head and neck cancer patients via activation of the Akt/mammalian target of rapamycin pathway.
    Nathan CO; Amirghahari N; Abreo F; Rong X; Caldito G; Jones ML; Zhou H; Smith M; Kimberly D; Glass J
    Clin Cancer Res; 2004 Sep; 10(17):5820-7. PubMed ID: 15355912
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Alcohol impairs insulin and IGF-I stimulation of S6K1 but not 4E-BP1 in skeletal muscle.
    Kumar V; Frost RA; Lang CH
    Am J Physiol Endocrinol Metab; 2002 Nov; 283(5):E917-28. PubMed ID: 12376318
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Hyperglycemia impairs the insulin signaling step between PI 3-kinase and Akt/PKB activations in ZDF rat liver.
    Nawano M; Ueta K; Oku A; Arakawa K; Saito A; Funaki M; Anai M; Kikuchi M; Oka Y; Asano T
    Biochem Biophys Res Commun; 1999 Dec; 266(1):252-6. PubMed ID: 10581198
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Acetaldehyde promotes rapamycin-dependent activation of p70(S6K) and glucose uptake despite inhibition of Akt and mTOR in dopaminergic SH-SY5Y human neuroblastoma cells.
    Fang CX; Yang X; Sreejayan N; Ren J
    Exp Neurol; 2007 Jan; 203(1):196-204. PubMed ID: 16962100
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Developmental regulation of the activation of signaling components leading to translation initiation in skeletal muscle of neonatal pigs.
    Suryawan A; Escobar J; Frank JW; Nguyen HV; Davis TA
    Am J Physiol Endocrinol Metab; 2006 Oct; 291(4):E849-59. PubMed ID: 16757550
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Role of the phosphoinositide 3-kinase-Akt-mammalian target of the rapamycin signaling pathway in long-term potentiation and trace fear conditioning memory in rat medial prefrontal cortex.
    Sui L; Wang J; Li BM
    Learn Mem; 2008 Oct; 15(10):762-76. PubMed ID: 18832563
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The phosphatidylinositol/AKT/atypical PKC pathway is involved in the improved insulin sensitivity by DHEA in muscle and liver of rats in vivo.
    Campbell CS; Caperuto LC; Hirata AE; Araujo EP; Velloso LA; Saad MJ; Carvalho CR
    Life Sci; 2004 Nov; 76(1):57-70. PubMed ID: 15501480
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Activation of mRNA translation in rat cardiac myocytes by insulin involves multiple rapamycin-sensitive steps.
    Wang L; Wang X; Proud CG
    Am J Physiol Heart Circ Physiol; 2000 Apr; 278(4):H1056-68. PubMed ID: 10749698
    [TBL] [Abstract][Full Text] [Related]  

  • 16. p53 activation results in rapid dephosphorylation of the eIF4E-binding protein 4E-BP1, inhibition of ribosomal protein S6 kinase and inhibition of translation initiation.
    Horton LE; Bushell M; Barth-Baus D; Tilleray VJ; Clemens MJ; Hensold JO
    Oncogene; 2002 Aug; 21(34):5325-34. PubMed ID: 12149653
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Regulation of targets of mTOR (mammalian target of rapamycin) signalling by intracellular amino acid availability.
    Beugnet A; Tee AR; Taylor PM; Proud CG
    Biochem J; 2003 Jun; 372(Pt 2):555-66. PubMed ID: 12611592
    [TBL] [Abstract][Full Text] [Related]  

  • 18. IGF-1-stimulated protein synthesis in oligodendrocyte progenitors requires PI3K/mTOR/Akt and MEK/ERK pathways.
    Bibollet-Bahena O; Almazan G
    J Neurochem; 2009 Jun; 109(5):1440-51. PubMed ID: 19453943
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Assessment of cell-signaling pathways in the regulation of mammalian target of rapamycin (mTOR) by amino acids in rat adipocytes.
    Pham PT; Heydrick SJ; Fox HL; Kimball SR; Jefferson LS; Lynch CJ
    J Cell Biochem; 2000 Sep; 79(3):427-41. PubMed ID: 10972980
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Meal feeding enhances formation of eIF4F in skeletal muscle: role of increased eIF4E availability and eIF4G phosphorylation.
    Vary TC; Lynch CJ
    Am J Physiol Endocrinol Metab; 2006 Apr; 290(4):E631-42. PubMed ID: 16263769
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.