BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

1746 related articles for article (PubMed ID: 12218097)

  • 1. Mitogen-activated protein kinase/extracellular signal-regulated kinase signaling in activated T cells abrogates TRAIL-induced apoptosis upstream of the mitochondrial amplification loop and caspase-8.
    Söderström TS; Poukkula M; Holmström TH; Heiskanen KM; Eriksson JE
    J Immunol; 2002 Sep; 169(6):2851-60. PubMed ID: 12218097
    [TBL] [Abstract][Full Text] [Related]  

  • 2. MAPK/ERK signaling in activated T cells inhibits CD95/Fas-mediated apoptosis downstream of DISC assembly.
    Holmström TH; Schmitz I; Söderström TS; Poukkula M; Johnson VL; Chow SC; Krammer PH; Eriksson JE
    EMBO J; 2000 Oct; 19(20):5418-28. PubMed ID: 11032809
    [TBL] [Abstract][Full Text] [Related]  

  • 3. TNF-related apoptosis-inducing ligand-induced apoptosis of melanoma is associated with changes in mitochondrial membrane potential and perinuclear clustering of mitochondria.
    Thomas WD; Zhang XD; Franco AV; Nguyen T; Hersey P
    J Immunol; 2000 Nov; 165(10):5612-20. PubMed ID: 11067917
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Intracellular mechanisms of TRAIL: apoptosis through mitochondrial-dependent and -independent pathways.
    Suliman A; Lam A; Datta R; Srivastava RK
    Oncogene; 2001 Apr; 20(17):2122-33. PubMed ID: 11360196
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Protein kinase C modulates tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by targeting the apical events of death receptor signaling.
    Harper N; Hughes MA; Farrow SN; Cohen GM; MacFarlane M
    J Biol Chem; 2003 Nov; 278(45):44338-47. PubMed ID: 12920112
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Epidermal growth factor protects epithelial-derived cells from tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by inhibiting cytochrome c release.
    Gibson EM; Henson ES; Haney N; Villanueva J; Gibson SB
    Cancer Res; 2002 Jan; 62(2):488-96. PubMed ID: 11809700
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Caspase-3 is a component of Fas death-inducing signaling complex in lipid rafts and its activity is required for complete caspase-8 activation during Fas-mediated cell death.
    Aouad SM; Cohen LY; Sharif-Askari E; Haddad EK; Alam A; Sekaly RP
    J Immunol; 2004 Feb; 172(4):2316-23. PubMed ID: 14764700
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Deoxycholic acid (DCA) causes ligand-independent activation of epidermal growth factor receptor (EGFR) and FAS receptor in primary hepatocytes: inhibition of EGFR/mitogen-activated protein kinase-signaling module enhances DCA-induced apoptosis.
    Qiao L; Studer E; Leach K; McKinstry R; Gupta S; Decker R; Kukreja R; Valerie K; Nagarkatti P; El Deiry W; Molkentin J; Schmidt-Ullrich R; Fisher PB; Grant S; Hylemon PB; Dent P
    Mol Biol Cell; 2001 Sep; 12(9):2629-45. PubMed ID: 11553704
    [TBL] [Abstract][Full Text] [Related]  

  • 9. TRAIL-mediated apoptosis requires NF-kappaB inhibition and the mitochondrial permeability transition in human hepatoma cells.
    Kim YS; Schwabe RF; Qian T; Lemasters JJ; Brenner DA
    Hepatology; 2002 Dec; 36(6):1498-508. PubMed ID: 12447876
    [TBL] [Abstract][Full Text] [Related]  

  • 10. JNK (c-Jun N-terminal kinase) and p38 activation in receptor-mediated and chemically-induced apoptosis of T-cells: differential requirements for caspase activation.
    MacFarlane M; Cohen GM; Dickens M
    Biochem J; 2000 May; 348 Pt 1(Pt 1):93-101. PubMed ID: 10794718
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Influence of casein kinase II in tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in human rhabdomyosarcoma cells.
    Izeradjene K; Douglas L; Delaney A; Houghton JA
    Clin Cancer Res; 2004 Oct; 10(19):6650-60. PubMed ID: 15475455
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Fas-associated death domain protein and caspase-8 are not recruited to the tumor necrosis factor receptor 1 signaling complex during tumor necrosis factor-induced apoptosis.
    Harper N; Hughes M; MacFarlane M; Cohen GM
    J Biol Chem; 2003 Jul; 278(28):25534-41. PubMed ID: 12721308
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Casein kinase I attenuates tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by regulating the recruitment of fas-associated death domain and procaspase-8 to the death-inducing signaling complex.
    Izeradjene K; Douglas L; Delaney AB; Houghton JA
    Cancer Res; 2004 Nov; 64(21):8036-44. PubMed ID: 15520213
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Stimulation of the mitogen-activated protein kinase pathway antagonizes TRAIL-induced apoptosis downstream of BID cleavage in human breast cancer MCF-7 cells.
    Sarker M; Ruiz-Ruiz C; Robledo G; López-Rivas A
    Oncogene; 2002 Jun; 21(27):4323-7. PubMed ID: 12082620
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Fas-associated death domain protein (FADD) and caspase-8 mediate up-regulation of c-Fos by Fas ligand and tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) via a FLICE inhibitory protein (FLIP)-regulated pathway.
    Siegmund D; Mauri D; Peters N; Juo P; Thome M; Reichwein M; Blenis J; Scheurich P; Tschopp J; Wajant H
    J Biol Chem; 2001 Aug; 276(35):32585-90. PubMed ID: 11384965
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Apo2L/TRAIL-dependent recruitment of endogenous FADD and caspase-8 to death receptors 4 and 5.
    Kischkel FC; Lawrence DA; Chuntharapai A; Schow P; Kim KJ; Ashkenazi A
    Immunity; 2000 Jun; 12(6):611-20. PubMed ID: 10894161
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Hepatitis C virus core protein modulates TRAIL-mediated apoptosis by enhancing Bid cleavage and activation of mitochondria apoptosis signaling pathway.
    Chou AH; Tsai HF; Wu YY; Hu CY; Hwang LH; Hsu PI; Hsu PN
    J Immunol; 2005 Feb; 174(4):2160-6. PubMed ID: 15699147
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Caspase-8 activation is necessary but not sufficient for tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis in the prostatic carcinoma cell line LNCaP.
    Rokhlin OW; Guseva NV; Tagiyev AF; Glover RA; Cohen MB
    Prostate; 2002 Jun; 52(1):1-11. PubMed ID: 11992615
    [TBL] [Abstract][Full Text] [Related]  

  • 19. MAPK/ERK overrides the apoptotic signaling from Fas, TNF, and TRAIL receptors.
    Tran SE; Holmstrom TH; Ahonen M; Kahari VM; Eriksson JE
    J Biol Chem; 2001 May; 276(19):16484-90. PubMed ID: 11278665
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Activation of ERK1/2 protects melanoma cells from TRAIL-induced apoptosis by inhibiting Smac/DIABLO release from mitochondria.
    Zhang XD; Borrow JM; Zhang XY; Nguyen T; Hersey P
    Oncogene; 2003 May; 22(19):2869-81. PubMed ID: 12771938
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 88.