These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
224 related articles for article (PubMed ID: 12218161)
1. Restriction of de novo pyrimidine biosynthesis inhibits Th1 cell activation and promotes Th2 cell differentiation. Dimitrova P; Skapenko A; Herrmann ML; Schleyerbach R; Kalden JR; Schulze-Koops H J Immunol; 2002 Sep; 169(6):3392-9. PubMed ID: 12218161 [TBL] [Abstract][Full Text] [Related]
2. Leflunomide inhibits pyrimidine de novo synthesis in mitogen-stimulated T-lymphocytes from healthy humans. Rückemann K; Fairbanks LD; Carrey EA; Hawrylowicz CM; Richards DF; Kirschbaum B; Simmonds HA J Biol Chem; 1998 Aug; 273(34):21682-91. PubMed ID: 9705303 [TBL] [Abstract][Full Text] [Related]
3. Strength of TCR signal determines the costimulatory requirements for Th1 and Th2 CD4+ T cell differentiation. Tao X; Constant S; Jorritsma P; Bottomly K J Immunol; 1997 Dec; 159(12):5956-63. PubMed ID: 9550393 [TBL] [Abstract][Full Text] [Related]
5. Mechanism of the antiproliferative action of leflunomide. A77 1726, the active metabolite of leflunomide, does not block T-cell receptor-mediated signal transduction but its antiproliferative effects are antagonized by pyrimidine nucleosides. Cao WW; Kao PN; Chao AC; Gardner P; Ng J; Morris RE J Heart Lung Transplant; 1995; 14(6 Pt 1):1016-30. PubMed ID: 8719445 [TBL] [Abstract][Full Text] [Related]
6. Inhibition of JAK3 and STAT6 tyrosine phosphorylation by the immunosuppressive drug leflunomide leads to a block in IgG1 production. Siemasko K; Chong AS; Jäck HM; Gong H; Williams JW; Finnegan A J Immunol; 1998 Feb; 160(4):1581-8. PubMed ID: 9469413 [TBL] [Abstract][Full Text] [Related]
7. 1,25-dihydroxyvitamin D3 inhibits IFN-gamma and IL-4 levels during in vitro polarization of primary murine CD4+ T cells. Staeva-Vieira TP; Freedman LP J Immunol; 2002 Feb; 168(3):1181-9. PubMed ID: 11801653 [TBL] [Abstract][Full Text] [Related]
8. C-C chemokine receptor 4 expression defines a major subset of circulating nonintestinal memory T cells of both Th1 and Th2 potential. Andrew DP; Ruffing N; Kim CH; Miao W; Heath H; Li Y; Murphy K; Campbell JJ; Butcher EC; Wu L J Immunol; 2001 Jan; 166(1):103-11. PubMed ID: 11123282 [TBL] [Abstract][Full Text] [Related]
9. Modulation of effector cell functions in experimental autoimmune encephalomyelitis by leflunomide--mechanisms independent of pyrimidine depletion. Korn T; Magnus T; Toyka K; Jung S J Leukoc Biol; 2004 Nov; 76(5):950-60. PubMed ID: 15328336 [TBL] [Abstract][Full Text] [Related]
10. Stability of Th1 and Th2 populations. Perez VL; Lederer JA; Lichtman AH; Abbas AK Int Immunol; 1995 May; 7(5):869-75. PubMed ID: 7547713 [TBL] [Abstract][Full Text] [Related]
11. Vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide stimulate the induction of Th2 responses by up-regulating B7.2 expression. Delgado M; Leceta J; Gomariz RP; Ganea D J Immunol; 1999 Oct; 163(7):3629-35. PubMed ID: 10490956 [TBL] [Abstract][Full Text] [Related]
12. In vitro and in vivo effects of leflunomide, brequinar, and cyclosporine on pyrimidine biosynthesis. Silva HT; Cao W; Shorthouse RA; Löffler M; Morris RE Transplant Proc; 1997; 29(1-2):1292-3. PubMed ID: 9123312 [No Abstract] [Full Text] [Related]
13. Antigen-independent Th2 cell differentiation by stimulation of CD28: regulation via IL-4 gene expression and mitogen-activated protein kinase activation. Skapenko A; Lipsky PE; Kraetsch HG; Kalden JR; Schulze-Koops H J Immunol; 2001 Apr; 166(7):4283-92. PubMed ID: 11254680 [TBL] [Abstract][Full Text] [Related]
14. Th1 development of naive CD4+ T cells is inhibited by co-activation with anti-CD4 monoclonal antibodies. Goedert S; Germann T; Hoehn P; Koelsch S; Palm N; Rüde E; Schmitt E J Immunol; 1996 Jul; 157(2):566-73. PubMed ID: 8752903 [TBL] [Abstract][Full Text] [Related]
15. Distinct biochemical signals characterize agonist- and altered peptide ligand-induced differentiation of naive CD4+ T cells into Th1 and Th2 subsets. Boutin Y; Leitenberg D; Tao X; Bottomly K J Immunol; 1997 Dec; 159(12):5802-9. PubMed ID: 9550376 [TBL] [Abstract][Full Text] [Related]
16. IL-12, as an adjuvant, promotes a T helper 1 cell, but does not suppress a T helper 2 cell recall response. Bliss J; Van Cleave V; Murray K; Wiencis A; Ketchum M; Maylor R; Haire T; Resmini C; Abbas AK; Wolf SF J Immunol; 1996 Feb; 156(3):887-94. PubMed ID: 8558014 [TBL] [Abstract][Full Text] [Related]
17. Ginsenoside Rg1 enhances CD4(+) T-cell activities and modulates Th1/Th2 differentiation. Lee EJ; Ko E; Lee J; Rho S; Ko S; Shin MK; Min BI; Hong MC; Kim SY; Bae H Int Immunopharmacol; 2004 Feb; 4(2):235-44. PubMed ID: 14996415 [TBL] [Abstract][Full Text] [Related]
18. CD2 facilitates differentiation of CD4 Th cells without affecting Th1/Th2 polarization. Sasada T; Yang H; Reinherz EL J Immunol; 2002 Feb; 168(3):1113-22. PubMed ID: 11801645 [TBL] [Abstract][Full Text] [Related]
19. Polarization of naive CD4+ T cells toward the Th1 subset by CTLA-4 costimulation. Kato T; Nariuchi H J Immunol; 2000 Apr; 164(7):3554-62. PubMed ID: 10725710 [TBL] [Abstract][Full Text] [Related]
20. Regulatory effect of nicotine on the differentiation of Th1, Th2 and Th17 lymphocyte subsets in patients with rheumatoid arthritis. Wu S; Zhou Y; Liu S; Zhang H; Luo H; Zuo X; Li T Eur J Pharmacol; 2018 Jul; 831():38-45. PubMed ID: 29715455 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]