BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

190 related articles for article (PubMed ID: 12221082)

  • 1. Galpha and Gbeta gamma require distinct Src-dependent pathways to activate Rap1 and Ras.
    Schmitt JM; Stork PJ
    J Biol Chem; 2002 Nov; 277(45):43024-32. PubMed ID: 12221082
    [TBL] [Abstract][Full Text] [Related]  

  • 2. beta 2-adrenergic receptor activates extracellular signal-regulated kinases (ERKs) via the small G protein rap1 and the serine/threonine kinase B-Raf.
    Schmitt JM; Stork PJ
    J Biol Chem; 2000 Aug; 275(33):25342-50. PubMed ID: 10840035
    [TBL] [Abstract][Full Text] [Related]  

  • 3. MAP kinase stimulation by cAMP does not require RAP1 but SRC family kinases.
    Klinger M; Kudlacek O; Seidel MG; Freissmuth M; Sexl V
    J Biol Chem; 2002 Sep; 277(36):32490-7. PubMed ID: 12082090
    [TBL] [Abstract][Full Text] [Related]  

  • 4. PKA phosphorylation of Src mediates Rap1 activation in NGF and cAMP signaling in PC12 cells.
    Obara Y; Labudda K; Dillon TJ; Stork PJ
    J Cell Sci; 2004 Dec; 117(Pt 25):6085-94. PubMed ID: 15546918
    [TBL] [Abstract][Full Text] [Related]  

  • 5. G protein-coupled receptor-mediated mitogen-activated protein kinase activation through cooperation of Galpha(q) and Galpha(i) signals.
    Blaukat A; Barac A; Cross MJ; Offermanns S; Dikic I
    Mol Cell Biol; 2000 Sep; 20(18):6837-48. PubMed ID: 10958680
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Ras-dependent ERK activation by the human G(s)-coupled serotonin receptors 5-HT4(b) and 5-HT7(a).
    Norum JH; Hart K; Levy FO
    J Biol Chem; 2003 Jan; 278(5):3098-104. PubMed ID: 12446729
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Glucose-dependent insulinotropic polypeptide activates the Raf-Mek1/2-ERK1/2 module via a cyclic AMP/cAMP-dependent protein kinase/Rap1-mediated pathway.
    Ehses JA; Pelech SL; Pederson RA; McIntosh CH
    J Biol Chem; 2002 Oct; 277(40):37088-97. PubMed ID: 12138104
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Dual regulation of Akt/protein kinase B by heterotrimeric G protein subunits.
    Bommakanti RK; Vinayak S; Simonds WF
    J Biol Chem; 2000 Dec; 275(49):38870-6. PubMed ID: 10986289
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Constitutively active Galpha16 stimulates STAT3 via a c-Src/JAK- and ERK-dependent mechanism.
    Lo RK; Cheung H; Wong YH
    J Biol Chem; 2003 Dec; 278(52):52154-65. PubMed ID: 14551213
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Regulator of G-protein signaling 3 (RGS3) inhibits Gbeta1gamma 2-induced inositol phosphate production, mitogen-activated protein kinase activation, and Akt activation.
    Shi CS; Lee SB; Sinnarajah S; Dessauer CW; Rhee SG; Kehrl JH
    J Biol Chem; 2001 Jun; 276(26):24293-300. PubMed ID: 11294858
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Activation of nuclear factor {kappa}B by somatostatin type 2 receptor in pancreatic acinar AR42J cells involves G{alpha}14 and multiple signaling components: a mechanism requiring protein kinase C, calmodulin-dependent kinase II, ERK, and c-Src.
    Liu AM; Wong YH
    J Biol Chem; 2005 Oct; 280(41):34617-25. PubMed ID: 16115892
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Protein Kinase A-independent Ras Protein Activation Cooperates with Rap1 Protein to Mediate Activation of the Extracellular Signal-regulated Kinases (ERK) by cAMP.
    Li Y; Dillon TJ; Takahashi M; Earley KT; Stork PJ
    J Biol Chem; 2016 Oct; 291(41):21584-21595. PubMed ID: 27531745
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Parallel regulation of mitogen-activated protein kinase kinase 3 (MKK3) and MKK6 in Gq-signaling cascade.
    Yamauchi J; Tsujimoto G; Kaziro Y; Itoh H
    J Biol Chem; 2001 Jun; 276(26):23362-72. PubMed ID: 11304531
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Extracellular signal-regulated kinase 1/2 activation by myometrial oxytocin receptor involves Galpha(q)Gbetagamma and epidermal growth factor receptor tyrosine kinase activation.
    Zhong M; Yang M; Sanborn BM
    Endocrinology; 2003 Jul; 144(7):2947-56. PubMed ID: 12810550
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Rap1-mediated activation of extracellular signal-regulated kinases by cyclic AMP is dependent on the mode of Rap1 activation.
    Wang Z; Dillon TJ; Pokala V; Mishra S; Labudda K; Hunter B; Stork PJ
    Mol Cell Biol; 2006 Mar; 26(6):2130-45. PubMed ID: 16507992
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Role of phosphoinositide 3-kinase and endocytosis in nerve growth factor-induced extracellular signal-regulated kinase activation via Ras and Rap1.
    York RD; Molliver DC; Grewal SS; Stenberg PE; McCleskey EW; Stork PJ
    Mol Cell Biol; 2000 Nov; 20(21):8069-83. PubMed ID: 11027277
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Both Gs and Gi proteins are critically involved in isoproterenol-induced cardiomyocyte hypertrophy.
    Zou Y; Komuro I; Yamazaki T; Kudoh S; Uozumi H; Kadowaki T; Yazaki Y
    J Biol Chem; 1999 Apr; 274(14):9760-70. PubMed ID: 10092665
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A CalDAG-GEFI/Rap1/B-Raf cassette couples M(1) muscarinic acetylcholine receptors to the activation of ERK1/2.
    Guo FF; Kumahara E; Saffen D
    J Biol Chem; 2001 Jul; 276(27):25568-81. PubMed ID: 11292831
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Rap1 is involved in cell stretching modulation of p38 but not ERK or JNK MAP kinase.
    Sawada Y; Nakamura K; Doi K; Takeda K; Tobiume K; Saitoh M; Morita K; Komuro I; De Vos K; Sheetz M; Ichijo H
    J Cell Sci; 2001 Mar; 114(Pt 6):1221-7. PubMed ID: 11228165
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Receptor isoforms mediate opposing proliferative effects through gbetagamma-activated p38 or Akt pathways.
    Sellers LA; Alderton F; Carruthers AM; Schindler M; Humphrey PP
    Mol Cell Biol; 2000 Aug; 20(16):5974-85. PubMed ID: 10913180
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.