469 related articles for article (PubMed ID: 12223581)
1. Early motor dysfunction and striosomal distribution of huntingtin microaggregates in Huntington's disease knock-in mice.
Menalled LB; Sison JD; Wu Y; Olivieri M; Li XJ; Li H; Zeitlin S; Chesselet MF
J Neurosci; 2002 Sep; 22(18):8266-76. PubMed ID: 12223581
[TBL] [Abstract][Full Text] [Related]
2. Time course of early motor and neuropathological anomalies in a knock-in mouse model of Huntington's disease with 140 CAG repeats.
Menalled LB; Sison JD; Dragatsis I; Zeitlin S; Chesselet MF
J Comp Neurol; 2003 Oct; 465(1):11-26. PubMed ID: 12926013
[TBL] [Abstract][Full Text] [Related]
3. Transgenic mice expressing mutated full-length HD cDNA: a paradigm for locomotor changes and selective neuronal loss in Huntington's disease.
Reddy PH; Charles V; Williams M; Miller G; Whetsell WO; Tagle DA
Philos Trans R Soc Lond B Biol Sci; 1999 Jun; 354(1386):1035-45. PubMed ID: 10434303
[TBL] [Abstract][Full Text] [Related]
4. Decrease in striatal enkephalin mRNA in mouse models of Huntington's disease.
Menalled L; Zanjani H; MacKenzie L; Koppel A; Carpenter E; Zeitlin S; Chesselet MF
Exp Neurol; 2000 Apr; 162(2):328-42. PubMed ID: 10739639
[TBL] [Abstract][Full Text] [Related]
5. Genetic background modifies nuclear mutant huntingtin accumulation and HD CAG repeat instability in Huntington's disease knock-in mice.
Lloret A; Dragileva E; Teed A; Espinola J; Fossale E; Gillis T; Lopez E; Myers RH; MacDonald ME; Wheeler VC
Hum Mol Genet; 2006 Jun; 15(12):2015-24. PubMed ID: 16687439
[TBL] [Abstract][Full Text] [Related]
6. The selective vulnerability of nerve cells in Huntington's disease.
Sieradzan KA; Mann DM
Neuropathol Appl Neurobiol; 2001 Feb; 27(1):1-21. PubMed ID: 11298997
[TBL] [Abstract][Full Text] [Related]
7. Changes in cortical and striatal neurons predict behavioral and electrophysiological abnormalities in a transgenic murine model of Huntington's disease.
Laforet GA; Sapp E; Chase K; McIntyre C; Boyce FM; Campbell M; Cadigan BA; Warzecki L; Tagle DA; Reddy PH; Cepeda C; Calvert CR; Jokel ES; Klapstein GJ; Ariano MA; Levine MS; DiFiglia M; Aronin N
J Neurosci; 2001 Dec; 21(23):9112-23. PubMed ID: 11717344
[TBL] [Abstract][Full Text] [Related]
8. Neocortical expression of mutant huntingtin is not required for alterations in striatal gene expression or motor dysfunction in a transgenic mouse.
Brown TB; Bogush AI; Ehrlich ME
Hum Mol Genet; 2008 Oct; 17(20):3095-104. PubMed ID: 18632688
[TBL] [Abstract][Full Text] [Related]
9. Huntingtin aggregate-associated axonal degeneration is an early pathological event in Huntington's disease mice.
Li H; Li SH; Yu ZX; Shelbourne P; Li XJ
J Neurosci; 2001 Nov; 21(21):8473-81. PubMed ID: 11606636
[TBL] [Abstract][Full Text] [Related]
10. A critical window of CAG repeat-length correlates with phenotype severity in the R6/2 mouse model of Huntington's disease.
Cummings DM; Alaghband Y; Hickey MA; Joshi PR; Hong SC; Zhu C; Ando TK; André VM; Cepeda C; Watson JB; Levine MS
J Neurophysiol; 2012 Jan; 107(2):677-91. PubMed ID: 22072510
[TBL] [Abstract][Full Text] [Related]
11. Characterization of neuron-specific huntingtin aggregates in human huntingtin knock-in mice.
Sawada H; Ishiguro H; Nishii K; Yamada K; Tsuchida K; Takahashi H; Goto J; Kanazawa I; Nagatsu T
Neurosci Res; 2007 Apr; 57(4):559-73. PubMed ID: 17335925
[TBL] [Abstract][Full Text] [Related]
12. Msh2 acts in medium-spiny striatal neurons as an enhancer of CAG instability and mutant huntingtin phenotypes in Huntington's disease knock-in mice.
Kovalenko M; Dragileva E; St Claire J; Gillis T; Guide JR; New J; Dong H; Kucherlapati R; Kucherlapati MH; Ehrlich ME; Lee JM; Wheeler VC
PLoS One; 2012; 7(9):e44273. PubMed ID: 22970194
[TBL] [Abstract][Full Text] [Related]
13. Transgenic rat model of Huntington's disease.
von Hörsten S; Schmitt I; Nguyen HP; Holzmann C; Schmidt T; Walther T; Bader M; Pabst R; Kobbe P; Krotova J; Stiller D; Kask A; Vaarmann A; Rathke-Hartlieb S; Schulz JB; Grasshoff U; Bauer I; Vieira-Saecker AM; Paul M; Jones L; Lindenberg KS; Landwehrmeyer B; Bauer A; Li XJ; Riess O
Hum Mol Genet; 2003 Mar; 12(6):617-24. PubMed ID: 12620967
[TBL] [Abstract][Full Text] [Related]
14. Mutant huntingtin's effects on striatal gene expression in mice recapitulate changes observed in human Huntington's disease brain and do not differ with mutant huntingtin length or wild-type huntingtin dosage.
Kuhn A; Goldstein DR; Hodges A; Strand AD; Sengstag T; Kooperberg C; Becanovic K; Pouladi MA; Sathasivam K; Cha JH; Hannan AJ; Hayden MR; Leavitt BR; Dunnett SB; Ferrante RJ; Albin R; Shelbourne P; Delorenzi M; Augood SJ; Faull RL; Olson JM; Bates GP; Jones L; Luthi-Carter R
Hum Mol Genet; 2007 Aug; 16(15):1845-61. PubMed ID: 17519223
[TBL] [Abstract][Full Text] [Related]
15. Characterization of HTT inclusion size, location, and timing in the zQ175 mouse model of Huntington's disease: an in vivo high-content imaging study.
Carty N; Berson N; Tillack K; Thiede C; Scholz D; Kottig K; Sedaghat Y; Gabrysiak C; Yohrling G; von der Kammer H; Ebneth A; Mack V; Munoz-Sanjuan I; Kwak S
PLoS One; 2015; 10(4):e0123527. PubMed ID: 25859666
[TBL] [Abstract][Full Text] [Related]
16. In vivo cell-autonomous transcriptional abnormalities revealed in mice expressing mutant huntingtin in striatal but not cortical neurons.
Thomas EA; Coppola G; Tang B; Kuhn A; Kim S; Geschwind DH; Brown TB; Luthi-Carter R; Ehrlich ME
Hum Mol Genet; 2011 Mar; 20(6):1049-60. PubMed ID: 21177255
[TBL] [Abstract][Full Text] [Related]
17. Striatal atrophy and dendritic alterations in a knock-in mouse model of Huntington's disease.
Lerner RP; Trejo Martinez Ldel C; Zhu C; Chesselet MF; Hickey MA
Brain Res Bull; 2012 Apr; 87(6):571-8. PubMed ID: 22326483
[TBL] [Abstract][Full Text] [Related]
18. Neurological abnormalities in a knock-in mouse model of Huntington's disease.
Lin CH; Tallaksen-Greene S; Chien WM; Cearley JA; Jackson WS; Crouse AB; Ren S; Li XJ; Albin RL; Detloff PJ
Hum Mol Genet; 2001 Jan; 10(2):137-44. PubMed ID: 11152661
[TBL] [Abstract][Full Text] [Related]
19. Proteasomal-dependent aggregate reversal and absence of cell death in a conditional mouse model of Huntington's disease.
Martín-Aparicio E; Yamamoto A; Hernández F; Hen R; Avila J; Lucas JJ
J Neurosci; 2001 Nov; 21(22):8772-81. PubMed ID: 11698589
[TBL] [Abstract][Full Text] [Related]
20. Mutant huntingtin causes context-dependent neurodegeneration in mice with Huntington's disease.
Yu ZX; Li SH; Evans J; Pillarisetti A; Li H; Li XJ
J Neurosci; 2003 Mar; 23(6):2193-202. PubMed ID: 12657678
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]