These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

149 related articles for article (PubMed ID: 12226485)

  • 1. Cell-specific expression of homospermidine synthase, the entry enzyme of the pyrrolizidine alkaloid pathway in Senecio vernalis, in comparison with its ancestor, deoxyhypusine synthase.
    Moll S; Anke S; Kahmann U; Hänsch R; Hartmann T; Ober D
    Plant Physiol; 2002 Sep; 130(1):47-57. PubMed ID: 12226485
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Homospermidine synthase, the first pathway-specific enzyme of pyrrolizidine alkaloid biosynthesis, evolved from deoxyhypusine synthase.
    Ober D; Hartmann T
    Proc Natl Acad Sci U S A; 1999 Dec; 96(26):14777-82. PubMed ID: 10611289
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Polyphyletic origin of pyrrolizidine alkaloids within the Asteraceae. Evidence from differential tissue expression of homospermidine synthase.
    Anke S; Niemüller D; Moll S; Hänsch R; Ober D
    Plant Physiol; 2004 Dec; 136(4):4037-47. PubMed ID: 15557091
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Repeated evolution of the pyrrolizidine alkaloid-mediated defense system in separate angiosperm lineages.
    Reimann A; Nurhayati N; Backenköhler A; Ober D
    Plant Cell; 2004 Oct; 16(10):2772-84. PubMed ID: 15466410
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Evolution of pyrrolizidine alkaloids in Phalaenopsis orchids and other monocotyledons: identification of deoxyhypusine synthase, homospermidine synthase and related pseudogenes.
    Nurhayati N; Gondé D; Ober D
    Phytochemistry; 2009 Mar; 70(4):508-16. PubMed ID: 19254800
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Phylogenetic origin of a secondary pathway: the case of pyrrolizidine alkaloids.
    Ober D; Hartmann T
    Plant Mol Biol; 2000 Nov; 44(4):445-50. PubMed ID: 11197320
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Recruitment of alkaloid-specific homospermidine synthase (HSS) from ubiquitous deoxyhypusine synthase: Does Crotalaria possess a functional HSS that still has DHS activity?
    Nurhayati N; Ober D
    Phytochemistry; 2005 Jun; 66(11):1346-57. PubMed ID: 15935411
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Identification of a Second Site of Pyrrolizidine Alkaloid Biosynthesis in Comfrey to Boost Plant Defense in Floral Stage
    Kruse LH; Stegemann T; Sievert C; Ober D
    Plant Physiol; 2017 May; 174(1):47-55. PubMed ID: 28275146
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Molecular evolution by change of function. Alkaloid-specific homospermidine synthase retained all properties of deoxyhypusine synthase except binding the eIF5A precursor protein.
    Ober D; Harms R; Witte L; Hartmann T
    J Biol Chem; 2003 Apr; 278(15):12805-12. PubMed ID: 12562768
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Development of an activity assay for characterizing deoxyhypusine synthase and its diverse reaction products.
    Kaltenegger E; Prakashrao AS; Çiçek SS; Ober D
    FEBS Open Bio; 2021 Jan; 11(1):10-25. PubMed ID: 33247548
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Distinct cell-specific expression of homospermidine synthase involved in pyrrolizidine alkaloid biosynthesis in three species of the boraginales.
    Niemüller D; Reimann A; Ober D
    Plant Physiol; 2012 Jul; 159(3):920-9. PubMed ID: 22566491
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Evidence for general occurrence of homospermidine in plants and its supposed origin as by-product of deoxyhypusine synthase.
    Ober D; Gibas L; Witte L; Hartmann T
    Phytochemistry; 2003 Feb; 62(3):339-44. PubMed ID: 12620346
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Reduction of Pyrrolizidine Alkaloid Levels in Comfrey (Symphytum officinale) Hairy Roots by RNAi Silencing of Homospermidine Synthase.
    Kruse LH; Stegemann T; Jensen-Kroll J; Engelhardt A; Wesseling AM; Lippert A; Ludwig-Müller J; Ober D
    Planta Med; 2019 Oct; 85(14-15):1177-1186. PubMed ID: 31450245
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Homospermidine in transgenic tobacco results in considerably reduced spermidine levels but is not converted to pyrrolizidine alkaloid precursors.
    Abdelhady MI; Beuerle T; Ober D
    Plant Mol Biol; 2009 Sep; 71(1-2):145-55. PubMed ID: 19543980
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Evolution of homospermidine synthase in the convolvulaceae: a story of gene duplication, gene loss, and periods of various selection pressures.
    Kaltenegger E; Eich E; Ober D
    Plant Cell; 2013 Apr; 25(4):1213-27. PubMed ID: 23572540
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Low pyrrolizidine alkaloid levels in perennial ryegrass is associated with the absence of a homospermidine synthase gene.
    Gill GP; Bryant CJ; Fokin M; Huege J; Fraser K; Jones C; Cao M; Faville MJ
    BMC Plant Biol; 2018 Apr; 18(1):56. PubMed ID: 29625552
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cloning and expression of a cDNA encoding homospermidine synthase from Senecio vulgaris (Asteraceae) in Escherichia coli.
    Kaiser A
    Plant J; 1999 Jul; 19(2):195-201. PubMed ID: 10476066
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Targeting enzymes involved in spermidine metabolism of parasitic protozoa--a possible new strategy for anti-parasitic treatment.
    Kaiser A; Gottwald A; Maier W; Seitz HM
    Parasitol Res; 2003 Dec; 91(6):508-16. PubMed ID: 14530966
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cloning and expression of homospermidine synthase from Senecio vulgaris: a revision.
    Ober D; Harms R; Hartmann T
    Phytochemistry; 2000 Oct; 55(4):305-9. PubMed ID: 11117877
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Pyrrolizidine alkaloid biosynthesis, evolution of a pathway in plant secondary metabolism.
    Ober D; Kaltenegger E
    Phytochemistry; 2009; 70(15-16):1687-95. PubMed ID: 19545881
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.