These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

91 related articles for article (PubMed ID: 12226841)

  • 1. Effect of guanidino modification and proline substitution on the in vitro stability and blood-brain barrier permeability of endomorphin II.
    Hau VS; Huber JD; Campos CR; Lipkowski AW; Misicka A; Davis TP
    J Pharm Sci; 2002 Oct; 91(10):2140-9. PubMed ID: 12226841
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Utilization of combined chemical modifications to enhance the blood-brain barrier permeability and pharmacological activity of endomorphin-1.
    Liu HM; Liu XF; Yao JL; Wang CL; Yu Y; Wang R
    J Pharmacol Exp Ther; 2006 Oct; 319(1):308-16. PubMed ID: 16803861
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Biological activity of endomorphin and [Dmt1]endomorphin analogs with six-membered proline surrogates in position 2.
    Perlikowska R; Gach K; Fichna J; Toth G; Walkowiak B; do-Rego JC; Janecka A
    Bioorg Med Chem; 2009 Jun; 17(11):3789-94. PubMed ID: 19435668
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structure-activity relationships of a series of [D-Ala2]deltorphin I and II analogues; in vitro blood-brain barrier permeability and stability.
    Thomas SA; Abbruscato TJ; Hau VS; Gillespie TJ; Zsigo J; Hruby VJ; Davis TP
    J Pharmacol Exp Ther; 1997 May; 281(2):817-25. PubMed ID: 9152390
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Characterization of antinociceptive activity of novel endomorphin-2 and morphiceptin analogs modified in the third position.
    Fichna J; do-Rego JC; Kosson P; Costentin J; Janecka A
    Biochem Pharmacol; 2005 Jan; 69(1):179-85. PubMed ID: 15588726
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis and biological evaluation of cyclic endomorphin-2 analogs.
    Perlikowska R; do-Rego JC; Cravezic A; Fichna J; Wyrebska A; Toth G; Janecka A
    Peptides; 2010 Feb; 31(2):339-45. PubMed ID: 19995587
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Transport characteristics of endomorphin-2 analogues in brain capillary endothelial cells.
    Mallareddy JR; Tóth G; Fazakas C; Molnár J; Nagyőszi P; Lipkowski AW; Krizbai IA; Wilhelm I
    Chem Biol Drug Des; 2012 Apr; 79(4):507-13. PubMed ID: 22181340
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Novel endomorphin analogues with antagonist activity at the mu-opioid receptor in the gastrointestinal tract.
    Fichna J; Gach K; Perlikowska R; Cravezic A; Bonnet JJ; do-Rego JC; Janecka A; Storr MA
    Regul Pept; 2010 Jun; 162(1-3):109-14. PubMed ID: 20083143
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Endomorphin-1 analogues (MELs) penetrate the blood-brain barrier and exhibit good analgesic effects with minimal side effects.
    Wang Y; Liu X; Wang D; Yang J; Zhao L; Yu J; Wang R
    Neuropharmacology; 2015 Oct; 97():312-21. PubMed ID: 26116761
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Novel glycosylated endomorphin-2 analog produces potent centrally-mediated antinociception in mice after peripheral administration.
    Fichna J; Mazur M; Grzywacz D; Kamysz W; Perlikowska R; Piekielna J; Sobczak M; Sałaga M; Toth G; Janecka A; Chen C; Olczak J
    Bioorg Med Chem Lett; 2013 Dec; 23(24):6673-6. PubMed ID: 24220171
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Pharmacological characterization of endomorphin-1 and endomorphin-2 in mouse brain.
    Goldberg IE; Rossi GC; Letchworth SR; Mathis JP; Ryan-Moro J; Leventhal L; Su W; Emmel D; Bolan EA; Pasternak GW
    J Pharmacol Exp Ther; 1998 Aug; 286(2):1007-13. PubMed ID: 9694962
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Antinociceptive and antidepressant-like action of endomorphin-2 analogs with proline surrogates in position 2.
    Perlikowska R; Piekielna J; Mazur M; Koralewski R; Olczak J; do Rego JC; Fichna J; Modranka J; Janecki T; Janecka A
    Bioorg Med Chem; 2014 Sep; 22(17):4803-9. PubMed ID: 25047937
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis and biological evaluation of novel peripherally active morphiceptin analogs.
    Gach K; do-Rego JC; Fichna J; Storr M; Delbro D; Toth G; Janecka A
    Peptides; 2010 Aug; 31(8):1617-24. PubMed ID: 20434497
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Peripheral antinociceptive effects of the cyclic endomorphin-1 analog c[YpwFG] in a mouse visceral pain model.
    Bedini A; Baiula M; Gentilucci L; Tolomelli A; De Marco R; Spampinato S
    Peptides; 2010 Nov; 31(11):2135-40. PubMed ID: 20713109
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Blood-brain barrier permeability and bioavailability of a highly potent and mu-selective opioid receptor antagonist, CTAP: comparison with morphine.
    Abbruscato TJ; Thomas SA; Hruby VJ; Davis TP
    J Pharmacol Exp Ther; 1997 Jan; 280(1):402-9. PubMed ID: 8996221
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Improved blood-brain barrier penetration and enhanced analgesia of an opioid peptide by glycosylation.
    Egleton RD; Mitchell SA; Huber JD; Palian MM; Polt R; Davis TP
    J Pharmacol Exp Ther; 2001 Dec; 299(3):967-72. PubMed ID: 11714884
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The improved blood-brain barrier permeability of endomorphin-1 using the cell-penetrating peptide synB3 with three different linkages.
    Liu H; Zhang W; Ma L; Fan L; Gao F; Ni J; Wang R
    Int J Pharm; 2014 Dec; 476(1-2):1-8. PubMed ID: 25245547
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Blood-brain barrier transport of a novel micro 1-specific opioid peptide, H-Tyr-D-Arg-Phe-beta-Ala-OH (TAPA).
    Deguchi Y; Miyakawa Y; Sakurada S; Naito Y; Morimoto K; Ohtsuki S; Hosoya K; Terasaki T
    J Neurochem; 2003 Mar; 84(5):1154-61. PubMed ID: 12603838
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Pharmacodynamic and pharmacokinetic characterization of poly(ethylene glycol) conjugation to met-enkephalin analog [D-Pen2, D-Pen5]-enkephalin (DPDPE).
    Witt KA; Huber JD; Egleton RD; Roberts MJ; Bentley MD; Guo L; Wei H; Yamamura HI; Davis TP
    J Pharmacol Exp Ther; 2001 Aug; 298(2):848-56. PubMed ID: 11454951
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Potent morphiceptin analogs: structure activity relationships and morphine-like activities.
    Chang KJ; Wei ET; Killian A; Chang JK
    J Pharmacol Exp Ther; 1983 Nov; 227(2):403-8. PubMed ID: 6313901
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.