These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

110 related articles for article (PubMed ID: 12227188)

  • 1. New 3-[4-(3-substituted phenyl)piperazin-1-yl]-1-(benzo[b]thiophen-3-yl)propanol derivatives with dual action at 5-HT1A serotonin receptors and serotonin transporter as a new class of antidepressants.
    Orús L; Martínez J; Pérez S; Oficialdegui AM; del Castillo JC; Mourelle M; Lasheras B; del Río J; Monge A
    Pharmazie; 2002 Aug; 57(8):515-8. PubMed ID: 12227188
    [TBL] [Abstract][Full Text] [Related]  

  • 2. New 3-[4-(aryl)piperazin-1-yl]-1-(benzo[b]thiophen-2-yl)propane derivatives with dual action at 5-HT1A serotonin receptors and serotonin transporter as a new class of antidepressants.
    Orús L; Sáinz Y; Pérez S; Oficialdegui AM; Martinez J; Lasheras B; del Río J; Monge A
    Pharmazie; 2002 Jun; 57(6):355-7. PubMed ID: 12116869
    [TBL] [Abstract][Full Text] [Related]  

  • 3. New 3-[4-(2,3-dihydro-14-benzodioxin-5-yl)piperazin-1-yl]-1-(5-substituted benzo[b]thiophen-3-yl)propanol derivatives with dual action at 5-HT(1A) serotonin receptors and serotonin transporter as a new class of antidepressants.
    Silanes SP; Orús L; Oficialdegui AM; Martínez Esparza J; Lasheras B; Del Río J; Monge A
    Pharmazie; 2004 Jul; 59(7):499-501. PubMed ID: 15296084
    [TBL] [Abstract][Full Text] [Related]  

  • 4. New 3-[4-(aryl)piperazin-1-yl]-1-(benzo[b]thiophen-3-yl)propane derivatives with dual action at 5-HT1A serotonin receptors and serotonin transporter as a new class of antidepressants.
    Martínez J; Pérez S; Oficialdegui AM; Heras B; Orús L; Villanueva H; Palop JA; Roca J; Mourelle M; Bosch A; Del Castillo JC; Lasheras B; Tordera R; del Río J; Monge A
    Eur J Med Chem; 2001 Jan; 36(1):55-61. PubMed ID: 11231049
    [TBL] [Abstract][Full Text] [Related]  

  • 5. New 1-aryl-3-(4-arylpiperazin-1-yl)propane derivatives, with dual action at 5-HT1A serotonin receptors and serotonin transporter, as a new class of antidepressants.
    Martínez-Esparza J; Oficialdegui AM; Pérez-Silanes S; Heras B; Orús L; Palop JA; Lasheras B; Roca J; Mourelle M; Bosch A; Del Castillo JC; Tordera R; Del Río J; Monge A
    J Med Chem; 2001 Feb; 44(3):418-28. PubMed ID: 11462981
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Isoindol-1-one analogues of 4-(2'-methoxyphenyl)-1-[2'-[N-(2"-pyridyl)-p-iodobenzamido]ethyl]pipera zine (p-MPPI) as 5-HT1A receptor ligands.
    Zhuang ZP; Kung MP; Mu M; Kung HF
    J Med Chem; 1998 Jan; 41(2):157-66. PubMed ID: 9457239
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Studies toward the discovery of the next generation of antidepressants. 3. Dual 5-HT1A and serotonin transporter affinity within a class of N-aryloxyethylindolylalkylamines.
    Mewshaw RE; Zhou D; Zhou P; Shi X; Hornby G; Spangler T; Scerni R; Smith D; Schechter LE; Andree TH
    J Med Chem; 2004 Jul; 47(15):3823-42. PubMed ID: 15239661
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Studies toward the discovery of the next generation of antidepressants. Part 2: incorporating a 5-HT(1A) antagonist component into a class of serotonin reuptake inhibitors.
    Mewshaw RE; Meagher KL; Zhou P; Zhou D; Shi X; Scerni R; Smith D; Schechter LE; Andree TH
    Bioorg Med Chem Lett; 2002 Feb; 12(3):307-10. PubMed ID: 11814784
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Neurotransmitter receptor and transporter binding profile of antidepressants and their metabolites.
    Owens MJ; Morgan WN; Plott SJ; Nemeroff CB
    J Pharmacol Exp Ther; 1997 Dec; 283(3):1305-22. PubMed ID: 9400006
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Studies toward the discovery of the next generation of antidepressants. Part 6: Dual 5-HT1A receptor and serotonin transporter affinity within a class of arylpiperazinyl-cyclohexyl indole derivatives.
    Zhou D; Zhou P; Evrard DA; Meagher K; Webb M; Harrison BL; Huryn DM; Golembieski J; Hornby GA; Schechter LE; Smith DL; Andree TH; Mewshaw RE
    Bioorg Med Chem; 2008 Jul; 16(14):6707-23. PubMed ID: 18571421
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis, monoamine transporter binding properties, and behavioral pharmacology of a series of 3beta-(substituted phenyl)-2beta-(3'-substituted isoxazol-5-yl)tropanes.
    Carroll FI; Pawlush N; Kuhar MJ; Pollard GT; Howard JL
    J Med Chem; 2004 Jan; 47(2):296-302. PubMed ID: 14711303
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Novel N-[omega-[4-(2-methoxyphenyl)piperazin-1-yl]-ethyl]pyrid-2(1H)-ones with diversified 5-HT1A receptor activity.
    Paluchowska MH; Bugno R; Charakchieva-Minol S; Wesołowska A; Chojnacka-Wójcik E
    Pol J Pharmacol; 2002; 54(6):641-6. PubMed ID: 12866719
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Modified ibogaine fragments: synthesis and preliminary pharmacological characterization of 3-ethyl-5-phenyl-1,2,3,4,5, 6-hexahydroazepino[4,5-b]benzothiophenes.
    Efange SM; Mash DC; Khare AB; Ouyang Q
    J Med Chem; 1998 Nov; 41(23):4486-91. PubMed ID: 9804688
    [TBL] [Abstract][Full Text] [Related]  

  • 14. [Second generation SSRIS: human monoamine transporter binding profile of escitalopram and R-fluoxetine].
    Owens JM; Knight DL; Nemeroff CB
    Encephale; 2002; 28(4):350-5. PubMed ID: 12232544
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Substitution mode of the amide fragment in some new N-[omega-[4-(2-methoxyphenyl)piperazin-1-yl]alkyl]pyrid-2(1H)-ones and their 5-HT1A/5-HT2A activity.
    Paluchowska MH; Bugno R; Charakchieva-Minol S; Bojarski AJ; Wesołowska A
    Pol J Pharmacol; 2001; 53(4):369-76. PubMed ID: 11990083
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Advances toward new antidepressants beyond SSRIs: 1-aryloxy-3-piperidinylpropan-2-ols with dual 5-HT1A receptor antagonism/SSRI activities. Part 1.
    Takeuchi K; Kohn TJ; Honigschmidt NA; Rocco VP; Spinazze PG; Koch DJ; Nelson DL; Wainscott DB; Ahmad LJ; Shaw J; Threlkeld PG; Wong DT
    Bioorg Med Chem Lett; 2003 Jun; 13(11):1903-5. PubMed ID: 12749894
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Design and synthesis of long-chain arylpiperazines with mixed affinity for serotonin transporter (SERT) and 5-HT(1A) receptor.
    Perrone R; Berardi F; Colabufo NA; Lacivita E; Larizza C; Leopoldo M; Tortorella V
    J Pharm Pharmacol; 2005 Oct; 57(10):1319-27. PubMed ID: 16259761
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Pharmacological characterization of N,N-dimethyl-2-(2-amino-4-methylphenyl thio)benzylamine as a ligand of the serotonin transporter with high affinity and selectivity.
    Chalon S; Tarkiainen J; Garreau L; Hall H; Emond P; Vercouillie J; Farde L; Dasse P; Varnas K; Besnard JC; Halldin C; Guilloteau D
    J Pharmacol Exp Ther; 2003 Jan; 304(1):81-7. PubMed ID: 12490578
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Calcium-dependent inhibition of synaptosomal serotonin transport by the alpha 2-adrenoceptor agonist 5-bromo-N-[4,5-dihydro-1H-imidazol-2-yl]-6-quinoxalinamine (UK14304).
    Ansah TA; Ramamoorthy S; Montañez S; Daws LC; Blakely RD
    J Pharmacol Exp Ther; 2003 Jun; 305(3):956-65. PubMed ID: 12626658
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Interaction of cis-(6-benzhydrylpiperidin-3-yl)benzylamine analogues with monoamine transporters: structure-activity relationship study of structurally constrained 3,6-disubstituted piperidine analogues of (2,2-diphenylethyl)-[1-(4-fluorobenzyl)piperidin-4-ylmethyl]amine.
    Kolhatkar RB; Ghorai SK; George C; Reith ME; Dutta AK
    J Med Chem; 2003 May; 46(11):2205-15. PubMed ID: 12747792
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.