BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

157 related articles for article (PubMed ID: 12228234)

  • 1. The human reduced folate carrier gene is regulated by the AP2 and sp1 transcription factor families and a functional 61-base pair polymorphism.
    Whetstine JR; Witt TL; Matherly LH
    J Biol Chem; 2002 Nov; 277(46):43873-80. PubMed ID: 12228234
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The basal promoters for the human reduced folate carrier gene are regulated by a GC-box and a cAMP-response element/AP-1-like element. Basis for tissue-specific gene expression.
    Whetstine JR; Matherly LH
    J Biol Chem; 2001 Mar; 276(9):6350-8. PubMed ID: 11078737
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Roles of USF, Ikaros and Sp proteins in the transcriptional regulation of the human reduced folate carrier B promoter.
    Liu M; Whetstine JR; Payton SG; Ge Y; Flatley RM; Matherly LH
    Biochem J; 2004 Oct; 383(Pt 2):249-57. PubMed ID: 15214842
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Alterations in the expression of transcription factors and the reduced folate carrier as a novel mechanism of antifolate resistance in human leukemia cells.
    Rothem L; Aronheim A; Assaraf YG
    J Biol Chem; 2003 Mar; 278(11):8935-41. PubMed ID: 12519783
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Transcriptional regulation of the human reduced folate carrier promoter C: synergistic transactivation by Sp1 and C/EBP beta and identification of a downstream repressor.
    Payton SG; Whetstine JR; Ge Y; Matherly LH
    Biochim Biophys Acta; 2005 Jan; 1727(1):45-57. PubMed ID: 15652157
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Transcriptional regulation of the human reduced folate carrier in childhood acute lymphoblastic leukemia cells.
    Liu M; Ge Y; Payton SG; Aboukameel A; Buck S; Flatley RM; Haska C; Mohammad R; Taub JW; Matherly LH
    Clin Cancer Res; 2006 Jan; 12(2):608-16. PubMed ID: 16428507
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Reduced folate carrier gene silencing in multiple antifolate-resistant tumor cell lines is due to a simultaneous loss of function of multiple transcription factors but not promoter methylation.
    Rothem L; Stark M; Kaufman Y; Mayo L; Assaraf YG
    J Biol Chem; 2004 Jan; 279(1):374-84. PubMed ID: 14551190
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The human reduced folate carrier gene is ubiquitously and differentially expressed in normal human tissues: identification of seven non-coding exons and characterization of a novel promoter.
    Whetstine JR; Flatley RM; Matherly LH
    Biochem J; 2002 Nov; 367(Pt 3):629-40. PubMed ID: 12144527
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Primary acute lymphoblastic leukemia cells use a novel promoter and 5'noncoding exon for the human reduced folate carrier that encodes a modified carrier translated from an upstream translational start.
    Flatley RM; Payton SG; Taub JW; Matherly LH
    Clin Cancer Res; 2004 Aug; 10(15):5111-22. PubMed ID: 15297414
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Overlapping Sp1 and AP2 binding sites in a promoter element of the lens-specific MIP gene.
    Ohtaka-Maruyama C; Wang X; Ge H; Chepelinsky AB
    Nucleic Acids Res; 1998 Jan; 26(2):407-14. PubMed ID: 9421492
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Transcriptional regulation of the human reduced folate carrier A1/A2 promoter: Identification of critical roles for the USF and GATA families of transcription factors.
    Payton SG; Liu M; Ge Y; Matherly LH
    Biochim Biophys Acta; 2005 Nov; 1731(2):115-24. PubMed ID: 16225938
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Species-specific mechanisms control the activity of the Pit1/PIT1 phosphate transporter gene promoter in mouse and human.
    Palmer G; Manen D; Bonjour JP; Caverzasio J
    Gene; 2001 Nov; 279(1):49-62. PubMed ID: 11722845
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cathepsin L gene expression and promoter activation in rodent granulosa cells.
    Sriraman V; Richards JS
    Endocrinology; 2004 Feb; 145(2):582-91. PubMed ID: 14563703
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structural and functional analysis of the human KB cell folate receptor gene P4 promoter: cooperation of three clustered Sp1-binding sites with initiator region for basal promoter activity.
    Saikawa Y; Price K; Hance KW; Chen TY; Elwood PC
    Biochemistry; 1995 Aug; 34(31):9951-61. PubMed ID: 7632694
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Sp1 and AP2 enhance promoter activity of the mouse GM3-synthase gene.
    Xia T; Zeng G; Gao L; Yu RK
    Gene; 2005 May; 351():109-18. PubMed ID: 15890474
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Characterization of the gene encoding a folate-binding protein expressed in human placenta. Identification of promoter activity in a G-rich SP1 site linked with the tandemly repeated GGAAG motif for the ets encoded GA-binding protein.
    Sadasivan E; Cedeno MM; Rothenberg SP
    J Biol Chem; 1994 Feb; 269(7):4725-35. PubMed ID: 8106441
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A CACCC box in the proximal exon 2 promoter of the rat insulin-like growth factor I gene is required for basal promoter activity.
    Wang X; Talamantez JL; Adamo ML
    Endocrinology; 1998 Mar; 139(3):1054-66. PubMed ID: 9492038
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The role of Sp1 family members, the proximal GC-rich motifs, and the upstream enhancer region in the regulation of the human cell cycle inhibitor p21WAF-1/Cip1 gene promoter.
    Koutsodontis G; Moustakas A; Kardassis D
    Biochemistry; 2002 Oct; 41(42):12771-84. PubMed ID: 12379120
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Nectin-2 expression in testicular cells is controlled via the functional cooperation between transcription factors of the Sp1, CREB, and AP-1 families.
    Lui WY; Sze KL; Lee WM
    J Cell Physiol; 2006 Apr; 207(1):144-57. PubMed ID: 16250013
    [TBL] [Abstract][Full Text] [Related]  

  • 20. c-Jun transactivates the promoter of the human p21(WAF1/Cip1) gene by acting as a superactivator of the ubiquitous transcription factor Sp1.
    Kardassis D; Papakosta P; Pardali K; Moustakas A
    J Biol Chem; 1999 Oct; 274(41):29572-81. PubMed ID: 10506225
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.