BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

122 related articles for article (PubMed ID: 12235248)

  • 1. Stereoselective metabolism of bufuralol racemate and enantiomers in human liver microsomes.
    Narimatsu S; Takemi C; Tsuzuki D; Kataoka H; Yamamoto S; Shimada N; Suzuki S; Satoh T; Meyer UA; Gonzalez FJ
    J Pharmacol Exp Ther; 2002 Oct; 303(1):172-8. PubMed ID: 12235248
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Stereoselectivity in the oxidation of bufuralol, a chiral substrate, by human cytochrome P450s.
    Narimatsu S; Takemi C; Kuramoto S; Tsuzuki D; Hichiya H; Tamagake K; Yamamoto S
    Chirality; 2003 May; 15(4):333-9. PubMed ID: 12666241
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The role of CYP2C19 in the metabolism of (+/-) bufuralol, the prototypic substrate of CYP2D6.
    Mankowski DC
    Drug Metab Dispos; 1999 Sep; 27(9):1024-8. PubMed ID: 10460802
    [TBL] [Abstract][Full Text] [Related]  

  • 4. (+)-bufuralol 1'-hydroxylation activity in human and rhesus monkey intestine and liver.
    Prueksaritanont T; Dwyer LM; Cribb AE
    Biochem Pharmacol; 1995 Oct; 50(9):1521-5. PubMed ID: 7503805
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Bufuralol hydroxylation by cytochrome P450 2D6 and 1A2 enzymes in human liver microsomes.
    Yamazaki H; Guo Z; Persmark M; Mimura M; Inoue K; Guengerich FP; Shimada T
    Mol Pharmacol; 1994 Sep; 46(3):568-77. PubMed ID: 7935340
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Stereoselective metabolism of cibenzoline, an antiarrhythmic drug, by human and rat liver microsomes: possible involvement of CYP2D and CYP3A.
    Niwa T; Shiraga T; Mitani Y; Terakawa M; Tokuma Y; Kagayama A
    Drug Metab Dispos; 2000 Sep; 28(9):1128-34. PubMed ID: 10950860
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Identification of human CYP isoforms involved in the metabolism of propranolol enantiomers--N-desisopropylation is mediated mainly by CYP1A2.
    Yoshimoto K; Echizen H; Chiba K; Tani M; Ishizaki T
    Br J Clin Pharmacol; 1995 Apr; 39(4):421-31. PubMed ID: 7640150
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Relationship between oxidative metabolism of 2-acetylaminofluorene, debrisoquine, bufuralol, and aldrin in human liver microsomes.
    McManus ME; Boobis AR; Minchin RF; Schwartz DM; Murray S; Davies DS; Thorgeirsson SS
    Cancer Res; 1984 Dec; 44(12 Pt 1):5692-7. PubMed ID: 6498831
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Role of CYP3A4 and CYP2C19 in the stereoselective metabolism of lansoprazole by human liver microsomes.
    Katsuki H; Hamada A; Nakamura C; Arimori K; Nakano M
    Eur J Clin Pharmacol; 2001 Dec; 57(10):709-15. PubMed ID: 11829200
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cloning and functional expression of a novel marmoset cytochrome P450 2D enzyme, CYP2D30: comparison with the known marmoset CYP2D19.
    Hichiya H; Kuramoto S; Yamamoto S; Shinoda S; Hanioka N; Narimatsu S; Asaoka K; Miyata A; Iwata S; Nomoto M; Satoh T; Kiryu K; Ueda N; Naito S; Tucker GT; Ellis SW
    Biochem Pharmacol; 2004 Jul; 68(1):165-75. PubMed ID: 15183128
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Characterization of (+/-)-bufuralol hydroxylation activities in liver microsomes of Japanese and Caucasian subjects genotyped for CYP2D6.
    Shimada T; Tsumura F; Yamazaki H; Guengerich FP; Inoue K
    Pharmacogenetics; 2001 Mar; 11(2):143-56. PubMed ID: 11266079
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Oxidative metabolism of 5-methoxy-N,N-diisopropyltryptamine (Foxy) by human liver microsomes and recombinant cytochrome P450 enzymes.
    Narimatsu S; Yonemoto R; Saito K; Takaya K; Kumamoto T; Ishikawa T; Asanuma M; Funada M; Kiryu K; Naito S; Yoshida Y; Yamamoto S; Hanioka N
    Biochem Pharmacol; 2006 Apr; 71(9):1377-85. PubMed ID: 16510126
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Different effects of desipramine on bufuralol 1''-hydroxylation by rat and human CYP2D enzymes.
    Isobe T; Hichiya H; Hanioka N; Yamamoto S; Shinoda S; Funae Y; Satoh T; Yamano S; Narimatsu S
    Biol Pharm Bull; 2005 Apr; 28(4):634-40. PubMed ID: 15802801
    [TBL] [Abstract][Full Text] [Related]  

  • 14. CYP1A2 and CYP2D6 4-hydroxylate propranolol and both reactions exhibit racial differences.
    Johnson JA; Herring VL; Wolfe MS; Relling MV
    J Pharmacol Exp Ther; 2000 Sep; 294(3):1099-105. PubMed ID: 10945865
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The molecular mechanisms of two common polymorphisms of drug oxidation--evidence for functional changes in cytochrome P-450 isozymes catalysing bufuralol and mephenytoin oxidation.
    Meyer UA; Gut J; Kronbach T; Skoda C; Meier UT; Catin T; Dayer P
    Xenobiotica; 1986 May; 16(5):449-64. PubMed ID: 2874666
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Regioselective and stereoselective oxidation of metoprolol and bufuralol catalyzed by microsomes containing cDNA-expressed human P4502D6.
    Mautz DS; Nelson WL; Shen DD
    Drug Metab Dispos; 1995 Apr; 23(4):513-7. PubMed ID: 7600921
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Differential roles of cytochromes P450 2D1, 2C11, and 1A1/2 in the hydroxylation of bufuralol by rat liver microsomes.
    Mimura M; Yamazaki H; Sugahara C; Hiroi T; Funae Y; Shimada T
    Biochem Pharmacol; 1994 Jun; 47(11):1957-63. PubMed ID: 7912070
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Identification of cytochrome P450 enzymes responsible for metabolism of cannabidiol by human liver microsomes.
    Jiang R; Yamaori S; Takeda S; Yamamoto I; Watanabe K
    Life Sci; 2011 Aug; 89(5-6):165-70. PubMed ID: 21704641
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Different contributions of cytochrome P450 2C19 and 3A4 in the oxidation of omeprazole by human liver microsomes: effects of contents of these two forms in individual human samples.
    Yamazaki H; Inoue K; Shaw PM; Checovich WJ; Guengerich FP; Shimada T
    J Pharmacol Exp Ther; 1997 Nov; 283(2):434-42. PubMed ID: 9353355
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Enantioselective and diastereoselective hydroxylation of bufuralol. Absolute configuration of the 7-(1-hydroxyethyl)-2-[1-hydroxy-2-(tert-butylamino)ethyl]benzofurans, the benzylic hydroxylation metabolites.
    Weerawarna SA; Geisshüsler SM; Murthy SS; Nelson WL
    J Med Chem; 1991 Oct; 34(10):3091-7. PubMed ID: 1681107
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.