320 related articles for article (PubMed ID: 12235278)
1. A cell-based reporter gene assay for determining induction of CYP3A4 in a high-volume system.
Raucy J; Warfe L; Yueh MF; Allen SW
J Pharmacol Exp Ther; 2002 Oct; 303(1):412-23. PubMed ID: 12235278
[TBL] [Abstract][Full Text] [Related]
2. A simultaneous assessment of CYP3A4 metabolism and induction in the DPX-2 cell line.
Trubetskoy O; Marks B; Zielinski T; Yueh MF; Raucy J
AAPS J; 2005 Mar; 7(1):E6-13. PubMed ID: 16146350
[TBL] [Abstract][Full Text] [Related]
3. The orphan human pregnane X receptor mediates the transcriptional activation of CYP3A4 by rifampicin through a distal enhancer module.
Goodwin B; Hodgson E; Liddle C
Mol Pharmacol; 1999 Dec; 56(6):1329-39. PubMed ID: 10570062
[TBL] [Abstract][Full Text] [Related]
4. Valproic acid induces CYP3A4 and MDR1 gene expression by activation of constitutive androstane receptor and pregnane X receptor pathways.
Cerveny L; Svecova L; Anzenbacherova E; Vrzal R; Staud F; Dvorak Z; Ulrichova J; Anzenbacher P; Pavek P
Drug Metab Dispos; 2007 Jul; 35(7):1032-41. PubMed ID: 17392393
[TBL] [Abstract][Full Text] [Related]
5. Rifampicin induction of CYP3A4 requires pregnane X receptor cross talk with hepatocyte nuclear factor 4alpha and coactivators, and suppression of small heterodimer partner gene expression.
Li T; Chiang JY
Drug Metab Dispos; 2006 May; 34(5):756-64. PubMed ID: 16455805
[TBL] [Abstract][Full Text] [Related]
6. Transcriptional control of intestinal cytochrome P-4503A by 1alpha,25-dihydroxy vitamin D3.
Thummel KE; Brimer C; Yasuda K; Thottassery J; Senn T; Lin Y; Ishizuka H; Kharasch E; Schuetz J; Schuetz E
Mol Pharmacol; 2001 Dec; 60(6):1399-406. PubMed ID: 11723248
[TBL] [Abstract][Full Text] [Related]
7. Endosulfan induces CYP2B6 and CYP3A4 by activating the pregnane X receptor.
Casabar RC; Das PC; Dekrey GK; Gardiner CS; Cao Y; Rose RL; Wallace AD
Toxicol Appl Pharmacol; 2010 Jun; 245(3):335-43. PubMed ID: 20361990
[TBL] [Abstract][Full Text] [Related]
8. Dual effect of dexamethasone on CYP3A4 gene expression in human hepatocytes. Sequential role of glucocorticoid receptor and pregnane X receptor.
Pascussi JM; Drocourt L; Gerbal-Chaloin S; Fabre JM; Maurel P; Vilarem MJ
Eur J Biochem; 2001 Dec; 268(24):6346-58. PubMed ID: 11737189
[TBL] [Abstract][Full Text] [Related]
9. Glucocorticoid-mediated induction of CYP3A4 is decreased by disruption of a protein: DNA interaction distinct from the pregnane X receptor response element.
El-Sankary W; Bombail V; Gibson GG; Plant N
Drug Metab Dispos; 2002 Sep; 30(9):1029-34. PubMed ID: 12167569
[TBL] [Abstract][Full Text] [Related]
10. Dexamethasone induces pregnane X receptor and retinoid X receptor-alpha expression in human hepatocytes: synergistic increase of CYP3A4 induction by pregnane X receptor activators.
Pascussi JM; Drocourt L; Fabre JM; Maurel P; Vilarem MJ
Mol Pharmacol; 2000 Aug; 58(2):361-72. PubMed ID: 10908304
[TBL] [Abstract][Full Text] [Related]
11. Azole antimycotics differentially affect rifampicin-induced pregnane X receptor-mediated CYP3A4 gene expression.
Svecova L; Vrzal R; Burysek L; Anzenbacherova E; Cerveny L; Grim J; Trejtnar F; Kunes J; Pour M; Staud F; Anzenbacher P; Dvorak Z; Pavek P
Drug Metab Dispos; 2008 Feb; 36(2):339-48. PubMed ID: 17998298
[TBL] [Abstract][Full Text] [Related]
12. A human and mouse pregnane X receptor reporter gene assay in combination with cytotoxicity measurements as a tool to evaluate species-specific CYP3A induction.
Vignati LA; Bogni A; Grossi P; Monshouwer M
Toxicology; 2004 Jun; 199(1):23-33. PubMed ID: 15125996
[TBL] [Abstract][Full Text] [Related]
13. Photochemotherapeutic agent 8-methoxypsoralen induces cytochrome P450 3A4 and carboxylesterase HCE2: evidence on an involvement of the pregnane X receptor.
Yang J; Yan B
Toxicol Sci; 2007 Jan; 95(1):13-22. PubMed ID: 17003103
[TBL] [Abstract][Full Text] [Related]
14. CYP3A4 induction by drugs: correlation between a pregnane X receptor reporter gene assay and CYP3A4 expression in human hepatocytes.
Luo G; Cunningham M; Kim S; Burn T; Lin J; Sinz M; Hamilton G; Rizzo C; Jolley S; Gilbert D; Downey A; Mudra D; Graham R; Carroll K; Xie J; Madan A; Parkinson A; Christ D; Selling B; LeCluyse E; Gan LS
Drug Metab Dispos; 2002 Jul; 30(7):795-804. PubMed ID: 12065438
[TBL] [Abstract][Full Text] [Related]
15. A PXR reporter gene assay in a stable cell culture system: CYP3A4 and CYP2B6 induction by pesticides.
Lemaire G; de Sousa G; Rahmani R
Biochem Pharmacol; 2004 Dec; 68(12):2347-58. PubMed ID: 15548381
[TBL] [Abstract][Full Text] [Related]
16. Dose-dependent induction of cytochrome P450 (CYP) 3A4 and activation of pregnane X receptor by topiramate.
Nallani SC; Glauser TA; Hariparsad N; Setchell K; Buckley DJ; Buckley AR; Desai PB
Epilepsia; 2003 Dec; 44(12):1521-8. PubMed ID: 14636322
[TBL] [Abstract][Full Text] [Related]
17. CYP3A4 inducible model for in vitro analysis of human drug metabolism using a bioartificial liver.
Iwahori T; Matsuura T; Maehashi H; Sugo K; Saito M; Hosokawa M; Chiba K; Masaki T; Aizaki H; Ohkawa K; Suzuki T
Hepatology; 2003 Mar; 37(3):665-73. PubMed ID: 12601364
[TBL] [Abstract][Full Text] [Related]
18. In vivo activation of the human CYP3A4 promoter in mouse liver and regulation by pregnane X receptors.
Zhang W; Purchio A; Chen K; Burns SM; Contag CH; Contag PR
Biochem Pharmacol; 2003 Jun; 65(11):1889-96. PubMed ID: 12781341
[TBL] [Abstract][Full Text] [Related]
19. Lower expression of HNF4α and PGC1α might impair rifampicin-mediated CYP3A4 induction under conditions where PXR is overexpressed in human fetal liver cells.
Takezawa T; Matsunaga T; Aikawa K; Nakamura K; Ohmori S
Drug Metab Pharmacokinet; 2012; 27(4):430-8. PubMed ID: 22333269
[TBL] [Abstract][Full Text] [Related]
20. Intestinal human colon adenocarcinoma cell line LS180 is an excellent model to study pregnane X receptor, but not constitutive androstane receptor, mediated CYP3A4 and multidrug resistance transporter 1 induction: studies with anti-human immunodeficiency virus protease inhibitors.
Gupta A; Mugundu GM; Desai PB; Thummel KE; Unadkat JD
Drug Metab Dispos; 2008 Jun; 36(6):1172-80. PubMed ID: 18332086
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
