BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

122 related articles for article (PubMed ID: 12237473)

  • 1. Changing the net charge from negative to positive makes ribonuclease Sa cytotoxic.
    Ilinskaya ON; Dreyer F; Mitkevich VA; Shaw KL; Pace CN; Makarov AA
    Protein Sci; 2002 Oct; 11(10):2522-5. PubMed ID: 12237473
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The effect of net charge on the solubility, activity, and stability of ribonuclease Sa.
    Shaw KL; Grimsley GR; Yakovlev GI; Makarov AA; Pace CN
    Protein Sci; 2001 Jun; 10(6):1206-15. PubMed ID: 11369859
    [TBL] [Abstract][Full Text] [Related]  

  • 3. [Cytotoxicity mechanism of the RNase Sa cationic mutants involves inhibition of potassium current through Ca2+-activated channels].
    Mitkevich VA; Pace CN; Koschinski A; Makarov AA; Ilinskaya ON
    Mol Biol (Mosk); 2015; 49(6):1041-7. PubMed ID: 26710788
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The role of protein stability, solubility, and net charge in amyloid fibril formation.
    Schmittschmitt JP; Scholtz JM
    Protein Sci; 2003 Oct; 12(10):2374-8. PubMed ID: 14500896
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Charge-charge interactions are key determinants of the pK values of ionizable groups in ribonuclease Sa (pI=3.5) and a basic variant (pI=10.2).
    Laurents DV; Huyghues-Despointes BM; Bruix M; Thurlkill RL; Schell D; Newsom S; Grimsley GR; Shaw KL; Treviño S; Rico M; Briggs JM; Antosiewicz JM; Scholtz JM; Pace CN
    J Mol Biol; 2003 Jan; 325(5):1077-92. PubMed ID: 12527309
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Molecular basis for nucleotide-binding specificity: role of the exocyclic amino group "N2" in recognition by a guanylyl-ribonuclease.
    Schrift GL; Waldron TT; Timmons MA; Ramaswamy S; Kearney WR; Murphy KP
    J Mol Biol; 2006 Jan; 355(1):72-84. PubMed ID: 16300786
    [TBL] [Abstract][Full Text] [Related]  

  • 7. pK values of histidine residues in ribonuclease Sa: effect of salt and net charge.
    Huyghues-Despointes BM; Thurlkill RL; Daily MD; Schell D; Briggs JM; Antosiewicz JM; Pace CN; Scholtz JM
    J Mol Biol; 2003 Jan; 325(5):1093-105. PubMed ID: 12527310
    [TBL] [Abstract][Full Text] [Related]  

  • 8. X-ray structure of two crystalline forms of a streptomycete ribonuclease with cytotoxic activity.
    Sevcik J; Urbanikova L; Leland PA; Raines RT
    J Biol Chem; 2002 Dec; 277(49):47325-30. PubMed ID: 12228255
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cloning and sequencing of the gene encoding a ribonuclease from Streptomyces aureofaciens CCM3239.
    Homerova D; Holländerova Z; Kormanec J; Sevcik J
    Gene; 1992 Sep; 119(1):147-8. PubMed ID: 1398084
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Crystal structure reveals two alternative conformations in the active site of ribonuclease Sa2.
    Sevcík J; Dauter Z; Wilson KS
    Acta Crystallogr D Biol Crystallogr; 2004 Jul; 60(Pt 7):1198-204. PubMed ID: 15213380
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Studies of the aggregation of RNase Sa.
    Khasa H; Kramer R; Maddux N; Hamborg M; Joshi SB; Volkin DB; Middaugh CR
    J Pharm Sci; 2014 Feb; 103(2):395-9. PubMed ID: 24382748
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Ribonuclease Sa conformational stability studied by NMR-monitored hydrogen exchange.
    Laurents DV; Scholtz JM; Rico M; Pace CN; Bruix M
    Biochemistry; 2005 May; 44(21):7644-55. PubMed ID: 15909979
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Zinc(II)-mediated inhibition of ribonuclease Sa by an N-hydroxyurea nucleotide and its basis.
    Makarov AA; Yakovlev GI; Mitkevich VA; Higgin JJ; Raines RT
    Biochem Biophys Res Commun; 2004 Jun; 319(1):152-6. PubMed ID: 15158454
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Conformational stability and thermodynamics of folding of ribonucleases Sa, Sa2 and Sa3.
    Pace CN; Hebert EJ; Shaw KL; Schell D; Both V; Krajcikova D; Sevcik J; Wilson KS; Dauter Z; Hartley RW; Grimsley GR
    J Mol Biol; 1998 May; 279(1):271-86. PubMed ID: 9636716
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Purification, crystallization and preliminary X-ray analysis of two crystal forms of ribonuclease Sa3.
    Hlinková V; Urbániková L; Krajcíková D; Sevcík J
    Acta Crystallogr D Biol Crystallogr; 2001 May; 57(Pt 5):737-9. PubMed ID: 11320322
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Cytotoxicity of RNases is increased by cationization and counteracted by K(Ca) channels.
    Ilinskaya ON; Koschinski A; Mitkevich VA; Repp H; Dreyer F; Pace CN; Makarov AA
    Biochem Biophys Res Commun; 2004 Feb; 314(2):550-4. PubMed ID: 14733942
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Charge-charge interactions in the denatured state influence the folding kinetics of ribonuclease Sa.
    Trefethen JM; Pace CN; Scholtz JM; Brems DN
    Protein Sci; 2005 Jul; 14(7):1934-8. PubMed ID: 15937282
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Crystal structure of the complex RNase Sa-barstar at 1.7 A resolution.
    Urbániková L; Sevcík J
    Gen Physiol Biophys; 1998 Jun; 17 Suppl 1():12-4. PubMed ID: 9789743
    [No Abstract]   [Full Text] [Related]  

  • 19. Contribution of active site residues to the activity and thermal stability of ribonuclease Sa.
    Yakovlev GI; Mitkevich VA; Shaw KL; Trevino S; Newsom S; Pace CN; Makarov AA
    Protein Sci; 2003 Oct; 12(10):2367-73. PubMed ID: 14500895
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Solution structure and dynamics of ribonuclease Sa.
    Laurents D; Pérez-Cañadillas JM; Santoro J; Rico M; Schell D; Pace CN; Bruix M
    Proteins; 2001 Aug; 44(3):200-11. PubMed ID: 11455593
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.