66 related articles for article (PubMed ID: 12237777)
21. Pharmacology of irinotecan.
Kuhn JG
Oncology (Williston Park); 1998 Aug; 12(8 Suppl 6):39-42. PubMed ID: 9726089
[TBL] [Abstract][Full Text] [Related]
22. Modifications of human carboxylesterase for improved prodrug activation.
Hatfield JM; Wierdl M; Wadkins RM; Potter PM
Expert Opin Drug Metab Toxicol; 2008 Sep; 4(9):1153-65. PubMed ID: 18721110
[TBL] [Abstract][Full Text] [Related]
23. Secreted and tumour targeted human carboxylesterase for activation of irinotecan.
Oosterhoff D; Pinedo HM; van der Meulen IH; de Graaf M; Sone T; Kruyt FA; van Beusechem VW; Haisma HJ; Gerritsen WR
Br J Cancer; 2002 Sep; 87(6):659-64. PubMed ID: 12237777
[TBL] [Abstract][Full Text] [Related]
24. Adenoviral vector-mediated expression of a gene encoding secreted, EpCAM-targeted carboxylesterase-2 sensitises colon cancer spheroids to CPT-11.
Oosterhoff D; Overmeer RM; de Graaf M; van der Meulen IH; Giaccone G; van Beusechem VW; Haisma HJ; Pinedo HM; Gerritsen WR
Br J Cancer; 2005 Mar; 92(5):882-7. PubMed ID: 15756257
[TBL] [Abstract][Full Text] [Related]
25. Tumor targeting carboxylesterase fused with anti-CEA scFv improve the anticancer effect with a less toxic dose of irinotecan.
Uchino J; Takayama K; Harada A; Sone T; Harada T; Curiel DT; Kuroki M; Nakanishi Y
Cancer Gene Ther; 2008 Feb; 15(2):94-100. PubMed ID: 18157147
[TBL] [Abstract][Full Text] [Related]
26. CPT-11 in human colon-cancer cell lines and xenografts: characterization of cellular sensitivity determinants.
Jansen WJ; Zwart B; Hulscher ST; Giaccone G; Pinedo HM; Boven E
Int J Cancer; 1997 Jan; 70(3):335-40. PubMed ID: 9033637
[TBL] [Abstract][Full Text] [Related]
27. Isolation and partial characterization of a cDNA encoding a rabbit liver carboxylesterase that activates the prodrug irinotecan (CPT-11).
Potter PM; Pawlik CA; Morton CL; Naeve CW; Danks MK
Cancer Res; 1998 Jun; 58(12):2646-51. PubMed ID: 9635592
[TBL] [Abstract][Full Text] [Related]
28. A fully human anti-Ep-CAM scFv-beta-glucuronidase fusion protein for selective chemotherapy with a glucuronide prodrug.
de Graaf M; Boven E; Oosterhoff D; van der Meulen-Muileman IH; Huls GA; Gerritsen WR; Haisma HJ; Pinedo HM
Br J Cancer; 2002 Mar; 86(5):811-8. PubMed ID: 11875747
[TBL] [Abstract][Full Text] [Related]
29. Sensitization of human tumor cells to CPT-11 via adenoviral-mediated delivery of a rabbit liver carboxylesterase.
Wierdl M; Morton CL; Weeks JK; Danks MK; Harris LC; Potter PM
Cancer Res; 2001 Jul; 61(13):5078-82. PubMed ID: 11431344
[TBL] [Abstract][Full Text] [Related]
30. Antineoplastic effect of anti-erbB-2 intrabody is not correlated with scFv affinity for its target.
Arafat W; Gómez-Navarro J; Xiang J; Siegal GP; Alvarez RD; Curiel DT
Cancer Gene Ther; 2000 Sep; 7(9):1250-6. PubMed ID: 11023197
[TBL] [Abstract][Full Text] [Related]
31. Characterization of CPT-11 hydrolysis by human liver carboxylesterase isoforms hCE-1 and hCE-2.
Humerickhouse R; Lohrbach K; Li L; Bosron WF; Dolan ME
Cancer Res; 2000 Mar; 60(5):1189-92. PubMed ID: 10728672
[TBL] [Abstract][Full Text] [Related]
32. Dexamethasone differentially regulates expression of carboxylesterase genes in humans and rats.
Zhu W; Song L; Zhang H; Matoney L; LeCluyse E; Yan B
Drug Metab Dispos; 2000 Feb; 28(2):186-91. PubMed ID: 10640517
[TBL] [Abstract][Full Text] [Related]
33. Comparison of activation of CPT-11 by rabbit and human carboxylesterases for use in enzyme/prodrug therapy.
Danks MK; Morton CL; Krull EJ; Cheshire PJ; Richmond LB; Naeve CW; Pawlik CA; Houghton PJ; Potter PM
Clin Cancer Res; 1999 Apr; 5(4):917-24. PubMed ID: 10213229
[TBL] [Abstract][Full Text] [Related]
34. A recombinant, fully human monoclonal antibody with antitumor activity constructed from phage-displayed antibody fragments.
Huls GA; Heijnen IA; Cuomo ME; Koningsberger JC; Wiegman L; Boel E; van der Vuurst de Vries AR; Loyson SA; Helfrich W; van Berge Henegouwen GP; van Meijer M; de Kruif J; Logtenberg T
Nat Biotechnol; 1999 Mar; 17(3):276-81. PubMed ID: 10096296
[TBL] [Abstract][Full Text] [Related]
35. Evaluation of irinotecan in combination with 5-fluorouracil or etoposide in xenograft models of colon adenocarcinoma and rhabdomyosarcoma.
Houghton JA; Cheshire PJ; Hallman JD; Lutz L; Luo X; Li Y; Houghton PJ
Clin Cancer Res; 1996 Jan; 2(1):107-18. PubMed ID: 9816097
[TBL] [Abstract][Full Text] [Related]
36.
; ; . PubMed ID:
[No Abstract] [Full Text] [Related]
37.
; ; . PubMed ID:
[No Abstract] [Full Text] [Related]
38.
; ; . PubMed ID:
[No Abstract] [Full Text] [Related]
39.
; ; . PubMed ID:
[No Abstract] [Full Text] [Related]
40.
; ; . PubMed ID:
[No Abstract] [Full Text] [Related]
[Previous] [Next] [New Search]