BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

308 related articles for article (PubMed ID: 12237873)

  • 1. Transcription factor E2F-1 acts as a growth-promoting factor and is associated with adverse prognosis in non-small cell lung carcinomas.
    Gorgoulis VG; Zacharatos P; Mariatos G; Kotsinas A; Bouda M; Kletsas D; Asimacopoulos PJ; Agnantis N; Kittas C; Papavassiliou AG
    J Pathol; 2002 Oct; 198(2):142-56. PubMed ID: 12237873
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Altered expression of the cell cycle regulatory molecules pRb, p53 and MDM2 exert a synergetic effect on tumor growth and chromosomal instability in non-small cell lung carcinomas (NSCLCs).
    Gorgoulis VG; Zacharatos P; Kotsinas A; Mariatos G; Liloglou T; Vogiatzi T; Foukas P; Rassidakis G; Garinis G; Ioannides T; Zoumpourlis V; Bramis J; Michail PO; Asimacopoulos PJ; Field JK; Kittas C
    Mol Med; 2000 Mar; 6(3):208-37. PubMed ID: 10965496
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Alterations of the p16-pRb pathway and the chromosome locus 9p21-22 in non-small-cell lung carcinomas: relationship with p53 and MDM2 protein expression.
    Gorgoulis VG; Zacharatos P; Kotsinas A; Liloglou T; Kyroudi A; Veslemes M; Rassidakis A; Halazonetis TD; Field JK; Kittas C
    Am J Pathol; 1998 Dec; 153(6):1749-65. PubMed ID: 9846966
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Overexpression of the replication licensing regulators hCdt1 and hCdc6 characterizes a subset of non-small-cell lung carcinomas: synergistic effect with mutant p53 on tumor growth and chromosomal instability--evidence of E2F-1 transcriptional control over hCdt1.
    Karakaidos P; Taraviras S; Vassiliou LV; Zacharatos P; Kastrinakis NG; Kougiou D; Kouloukoussa M; Nishitani H; Papavassiliou AG; Lygerou Z; Gorgoulis VG
    Am J Pathol; 2004 Oct; 165(4):1351-65. PubMed ID: 15466399
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Distinct expression patterns of the transcription factor E2F-1 in relation to tumour growth parameters in common human carcinomas.
    Zacharatos P; Kotsinas A; Evangelou K; Karakaidos P; Vassiliou LV; Rezaei N; Kyroudi A; Kittas C; Patsouris E; Papavassiliou AG; Gorgoulis VG
    J Pathol; 2004 Jul; 203(3):744-53. PubMed ID: 15221933
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Deregulated expression of c-mos in non-small cell lung carcinomas: relationship with p53 status, genomic instability, and tumor kinetics.
    Gorgoulis VG; Zacharatos P; Mariatos G; Liloglou T; Kokotas S; Kastrinakis N; Kotsinas A; Athanasiou A; Foukas P; Zoumpourlis V; Kletsas D; Ikonomopoulos J; Asimacopoulos PJ; Kittas C; Field JK
    Cancer Res; 2001 Jan; 61(2):538-49. PubMed ID: 11212247
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Functional interplay between p53 and E2F through co-activator p300.
    Lee CW; Sørensen TS; Shikama N; La Thangue NB
    Oncogene; 1998 May; 16(21):2695-710. PubMed ID: 9652736
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Gene amplification is a relatively frequent event leading to ZBTB7A (Pokemon) overexpression in non-small cell lung cancer.
    Apostolopoulou K; Pateras IS; Evangelou K; Tsantoulis PK; Liontos M; Kittas C; Tiniakos DG; Kotsinas A; Cordon-Cardo C; Gorgoulis VG
    J Pathol; 2007 Nov; 213(3):294-302. PubMed ID: 17907153
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Association of allelic loss at the FHIT locus and p53 alterations with tumour kinetics and chromosomal instability in non-small cell lung carcinomas (NSCLCs).
    Garinis GA; Gorgoulis VG; Mariatos G; Zacharatos P; Kotsinas A; Liloglou T; Foukas P; Kanavaros P; Kastrinakis NG; Vassilakopoulos T; Vogiatzi T; Field JK; Kittas C
    J Pathol; 2001 Jan; 193(1):55-65. PubMed ID: 11169516
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Increased E2F-1 expression via tumour cell proliferation and decreased apoptosis are correlated with adverse prognosis in patients with squamous cell carcinoma of the oesophagus.
    Yamazaki K; Hasegawa M; Ohoka I; Hanami K; Asoh A; Nagao T; Sugano I; Ishida Y
    J Clin Pathol; 2005 Sep; 58(9):904-10. PubMed ID: 16126868
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Low levels of p27 in association with deregulated p53-pRb protein status enhance tumor proliferation and chromosomal instability in non-small cell lung carcinomas.
    Tsoli E; Gorgoulis VG; Zacharatos P; Kotsinas A; Mariatos G; Kastrinakis NG; Kokotas S; Kanavaros P; Asimacopoulos P; Bramis J; Kletsas D; Papavassiliou AG; Kittas C
    Mol Med; 2001 Jun; 7(6):418-29. PubMed ID: 11474135
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Alterations of p14ARF, p53, and p73 genes involved in the E2F-1-mediated apoptotic pathways in non-small cell lung carcinoma.
    Nicholson SA; Okby NT; Khan MA; Welsh JA; McMenamin MG; Travis WD; Jett JR; Tazelaar HD; Trastek V; Pairolero PC; Corn PG; Herman JG; Liotta LA; Caporaso NE; Harris CC
    Cancer Res; 2001 Jul; 61(14):5636-43. PubMed ID: 11454718
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Adenovirus-mediated E2F-1 gene transfer inhibits MDM2 expression and efficiently induces apoptosis in MDM2-overexpressing tumor cells.
    Yang HL; Dong YB; Elliott MJ; Liu TJ; Atienza C; Stilwell A; McMasters KM
    Clin Cancer Res; 1999 Aug; 5(8):2242-50. PubMed ID: 10473112
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Disruption of the pRb/E2F pathway and inhibition of apoptosis are major oncogenic events in liver constitutively expressing c-myc and transforming growth factor alpha.
    Santoni-Rugiu E; Jensen MR; Thorgeirsson SS
    Cancer Res; 1998 Jan; 58(1):123-34. PubMed ID: 9426068
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Association of allelic imbalance at locus D13S171 (BRCA2) and p53 alterations with tumor kinetics and chromosomal instability (aneuploidy) in nonsmall cell lung carcinoma.
    Gorgoulis VG; Kotsinas A; Zacharatos P; Mariatos G; Liloglou T; Tsoli E; Kokotas S; Fassoulas C; Field JK; Kittas C
    Cancer; 2000 Nov; 89(9):1933-45. PubMed ID: 11064350
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Induction of apoptosis in human esophageal cancer cells by sequential transfer of the wild-type p53 and E2F-1 genes: involvement of p53 accumulation via ARF-mediated MDM2 down-regulation.
    Itoshima T; Fujiwara T; Waku T; Shao J; Kataoka M; Yarbrough WG; Liu TJ; Roth JA; Tanaka N; Kodama M
    Clin Cancer Res; 2000 Jul; 6(7):2851-9. PubMed ID: 10914734
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Tumor suppressor TAp73 gene specifically responds to deregulated E2F activity in human normal fibroblasts.
    Ozono E; Komori H; Iwanaga R; Tanaka T; Sakae T; Kitamura H; Yamaoka S; Ohtani K
    Genes Cells; 2012 Aug; 17(8):660-72. PubMed ID: 22702391
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Novel link between E2F and p53: proapoptotic cofactors of p53 are transcriptionally upregulated by E2F.
    Hershko T; Chaussepied M; Oren M; Ginsberg D
    Cell Death Differ; 2005 Apr; 12(4):377-83. PubMed ID: 15706352
    [TBL] [Abstract][Full Text] [Related]  

  • 19. TRIP-Br: a novel family of PHD zinc finger- and bromodomain-interacting proteins that regulate the transcriptional activity of E2F-1/DP-1.
    Hsu SI; Yang CM; Sim KG; Hentschel DM; O'Leary E; Bonventre JV
    EMBO J; 2001 May; 20(9):2273-85. PubMed ID: 11331592
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Molecular control of the cell cycle in cancer: biological and clinical aspects.
    Møller MB
    Dan Med Bull; 2003 May; 50(2):118-38. PubMed ID: 12812137
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.