BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

149 related articles for article (PubMed ID: 12238528)

  • 1. Comparative study of bis(benzyl)phosphate triesters of 2',3'-dideoxy-2',3'-didehydrothymidine (d4T) and cyclosal-d4TMP--hydrolysis, mechanistic insights and anti-HIV activity.
    Meier C; Muus U; Renze J; Naesens L; De Clercq E; Balzarini J
    Antivir Chem Chemother; 2002 Mar; 13(2):101-14. PubMed ID: 12238528
    [TBL] [Abstract][Full Text] [Related]  

  • 2. cycloSal-2',3'-dideoxy-2',3'-didehydrothymidine monophosphate (cycloSal-d4TMP): synthesis and antiviral evaluation of a new d4TMP delivery system.
    Meier C; Lorey M; De Clercq E; Balzarini J
    J Med Chem; 1998 Apr; 41(9):1417-27. PubMed ID: 9554875
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Aryl-substituted and benzo-annulated cyc/osal-derivatives of 2',3'-dideoxy-2',3'-didehydrothymidine monophosphate--correlation of structure, hydrolysis properties and anti-HIV activity.
    Ducho C; Balzarini J; Naesens L; De Clercq E; Meier C
    Antivir Chem Chemother; 2002 Mar; 13(2):129-41. PubMed ID: 12238530
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Bis-cycloSal-d4T-monophosphates: drugs that deliver two molecules of bioactive nucleotides.
    Ducho C; Görbig U; Jessel S; Gisch N; Balzarini J; Meier C
    J Med Chem; 2007 Mar; 50(6):1335-46. PubMed ID: 17328534
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Study of different substituted cyclic and acyclic benzylpronucleotides of d4T relative to their hydrolytic stability and antiviral activity.
    Muus U; De Clercq E; Balzarini J; Naesens L; Meier C
    Nucleosides Nucleotides Nucleic Acids; 2003; 22(5-8):791-5. PubMed ID: 14565280
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Enzymatically activated cycloSal-d4T-monophosphates: The third generation of cycloSal-pronucleotides.
    Gisch N; Balzarini J; Meier C
    J Med Chem; 2007 Apr; 50(7):1658-67. PubMed ID: 17335187
    [TBL] [Abstract][Full Text] [Related]  

  • 7. d4TMP delivery from 7-substituted cycloSal-d4TMPs.
    Meier C; Renze JT; Balzarini J; De Clercq E
    Nucleosides Nucleotides Nucleic Acids; 2003; 22(5-8):825-7. PubMed ID: 14565288
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Cyclosaligenyl-2',3'-didehydro-2',3'-dideoxythymidine monophosphate: efficient intracellular delivery of d4TMP.
    Balzarini J; Aquaro S; Knispel T; Rampazzo C; Bianchi V; Perno CF; De Clercq E; Meier C
    Mol Pharmacol; 2000 Nov; 58(5):928-35. PubMed ID: 11040039
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Benzyl-functionalized cycloSal-d4T monophosphates.
    Renze J; Plath M; Ducho C; Balzarini J; De Clercq E; Meier C
    Nucleosides Nucleotides Nucleic Acids; 2001; 20(4-7):931-4. PubMed ID: 11563147
    [TBL] [Abstract][Full Text] [Related]  

  • 10. 5-(1-Acetoxyvinyl)-cycloSaligenyl-2',3'-dideoxy-2',3'- didehydrothymidine monophosphates, a second type of new, enzymatically activated cycloSaligenyl pronucleotides.
    Gisch N; Pertenbreiter F; Balzarini J; Meier C
    J Med Chem; 2008 Dec; 51(24):8115-23. PubMed ID: 19053827
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Stereoselective synthesis and antiviral activity of methyl-substituted cycloSal-pronucleotides.
    Rios Morales EH; Balzarini J; Meier C
    J Med Chem; 2012 Aug; 55(16):7245-52. PubMed ID: 22827702
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Doubly loaded cycloSaligenyl-pronucleotides - 5,5'-Bis-(cycloSaligenyl-2',3'-dideoxy-2',3'-didehydrothymidine monophosphates).
    Gisch N; Balzarini J; Meier C
    J Med Chem; 2009 Jun; 52(11):3464-73. PubMed ID: 19438207
    [TBL] [Abstract][Full Text] [Related]  

  • 13. cycloSal-d4TMP pronucleotides structural variations, mechanistic insights and antiviral activity.
    Meiera C; Renzea J; Ducho C; Balzarini J
    Curr Top Med Chem; 2002 Oct; 2(10):1111-21. PubMed ID: 12173970
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Bis-ketol nucleoside triesters as prodrugs of the antiviral nucleoside triphosphate analogues of 3'-deoxythymidine and 3'-deoxy-2',3'-didehydrothymidine.
    Calvo KC; Wang X; Koser GF
    Nucleosides Nucleotides Nucleic Acids; 2004; 23(3):637-46. PubMed ID: 15113029
    [TBL] [Abstract][Full Text] [Related]  

  • 15. New developments of the "lock-in" modified cycloSal-d4TMPs.
    Vukadinović-Tenter D; Balzarini J; Meier C
    Nucleosides Nucleotides Nucleic Acids; 2007; 26(10-12):1325-8. PubMed ID: 18066777
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Cyclosal-pronucleotides--development of first and second generation chemical trojan horses for antiviral chemotherapy.
    Meier C; Meerbach A; Balzarini J
    Front Biosci; 2004 Jan; 9():873-90. PubMed ID: 14766416
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Characterization of the activation pathway of phosphoramidate triester prodrugs of stavudine and zidovudine.
    Saboulard D; Naesens L; Cahard D; Salgado A; Pathirana R; Velazquez S; McGuigan C; De Clercq E; Balzarini J
    Mol Pharmacol; 1999 Oct; 56(4):693-704. PubMed ID: 10496951
    [TBL] [Abstract][Full Text] [Related]  

  • 18. cycloSal-Pronucleotides of 2',3'-dideoxyadenosine and 2', 3'-dideoxy-2',3'-didehydroadenosine: synthesis and antiviral evaluation of a highly efficient nucleotide delivery system.
    Meier C; Knispel T; De Clercq E; Balzarini J
    J Med Chem; 1999 May; 42(9):1604-14. PubMed ID: 10229629
    [TBL] [Abstract][Full Text] [Related]  

  • 19. 5-diacetoxymethyl-cycloSal-d4TMP - A prototype of enzymatically activated cycloSal-pronucleotides.
    Gisch N; Balzarini J; Meier C
    Nucleosides Nucleotides Nucleic Acids; 2007; 26(6-7):861-4. PubMed ID: 18066914
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Studies on enzyme-cleavable dialkoxymethyl-cyclosaligenyl-2',3'-dideoxy-2',3'-didehydrothymidine monophosphates.
    Gisch N; Balzarini J; Meier C
    J Med Chem; 2008 Nov; 51(21):6752-60. PubMed ID: 18834186
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.