These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

76 related articles for article (PubMed ID: 12240115)

  • 1. Multi-component assembly of the bicyclic core associated with the tRNA synthetase inhibitors SB-203207 and SB-203208. Application to the synthesis of biologically active analogues.
    Banwell MG; Crasto CF; Easton CJ; Karoli T; March DR; Nairn MR; O'Hanlon PJ; Oldham MD; Willis AC; Yue W
    Chem Commun (Camb); 2001 Nov; (21):2210-1. PubMed ID: 12240115
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Analogues of SB-203207 as inhibitors of tRNA synthetases.
    Banwell MG; Crasto CF; Easton CJ; Forrest AK; Karoli T; March DR; Mensah L; Nairn MR; O'Hanlon PJ; Oldham MD; Yue W
    Bioorg Med Chem Lett; 2000 Oct; 10(20):2263-6. PubMed ID: 11055334
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis and activity of analogues of the isoleucyl tRNA synthetase inhibitor SB-203207.
    Crasto CF; Forrest AK; Karoli T; March DR; Mensah L; O'Hanlon PJ; Nairn MR; Oldham MD; Yue W; Banwell MG; Easton CJ
    Bioorg Med Chem; 2003 Jul; 11(13):2687-94. PubMed ID: 12788342
    [TBL] [Abstract][Full Text] [Related]  

  • 4. SB-203207 and SB-203208, two novel isoleucyl tRNA synthetase inhibitors from a Streptomyces sp. I. Fermentation, isolation and properties.
    Stefanska AL; Cassels R; Ready SJ; Warr SR
    J Antibiot (Tokyo); 2000 Apr; 53(4):357-63. PubMed ID: 10866217
    [TBL] [Abstract][Full Text] [Related]  

  • 5. SB-203207 and SB-203208, two novel isoleucyl tRNA synthetase inhibitors from a Streptomyces sp. II. Structure determination.
    Houge-Frydrych CS; Gilpin ML; Skett PW; Tyler JW
    J Antibiot (Tokyo); 2000 Apr; 53(4):364-72. PubMed ID: 10866218
    [TBL] [Abstract][Full Text] [Related]  

  • 6. 5'-(N-aminoacyl)-sulfonamido-5'-deoxyadenosine: attempts for a stable alternative for aminoacyl-sulfamoyl adenosines as aaRS inhibitors.
    Gadakh B; Smaers S; Rozenski J; Froeyen M; Van Aerschot A
    Eur J Med Chem; 2015 Mar; 93():227-36. PubMed ID: 25686591
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A facile three-component one-pot synthesis of structurally constrained tetrahydrofurans that are t-RNA synthetase inhibitor analogues.
    Lu CD; Chen ZY; Liu H; Hu WH; Mi AQ; Doyle MP
    J Org Chem; 2004 Jul; 69(14):4856-9. PubMed ID: 15230617
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Use of the kinetic equilibrium between aminoacyl-tRNA formation and hydrolysis in inhibition assays of aminoacyl-tRNA synthetase.
    Jordan DB; Abell LM; Picollelli MA; Senator DR; Mason JL; Rogers MJ; Rendina AR
    Anal Biochem; 2001 Nov; 298(1):133-6. PubMed ID: 11673908
    [No Abstract]   [Full Text] [Related]  

  • 9. Aminoalkyl adenylate and aminoacyl sulfamate intermediate analogues differing greatly in affinity for their cognate Staphylococcus aureus aminoacyl tRNA synthetases.
    Forrest AK; Jarvest RL; Mensah LM; O'Hanlon PJ; Pope AJ; Sheppard RJ
    Bioorg Med Chem Lett; 2000 Aug; 10(16):1871-4. PubMed ID: 10969988
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis of 8-aminoadenosine 5'-(aminoalkyl phosphates), analogues of aminoacyl adenylates.
    Yousefi-Salakdeh E; Murtola M; Zetterberg A; Yeheskiely E; Strömberg R
    Bioorg Med Chem; 2006 Apr; 14(8):2653-9. PubMed ID: 16368242
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis and aminoacyl-tRNA synthetase inhibitory activity of aspartyl adenylate analogs.
    Bernier S; Akochy PM; Lapointe J; Chênevert R
    Bioorg Med Chem; 2005 Jan; 13(1):69-75. PubMed ID: 15582453
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Bisphosphonates are incorporated into adenine nucleotides by human aminoacyl-tRNA synthetase enzymes.
    Rogers MJ; Brown RJ; Hodkin V; Blackburn GM; Russell RG; Watts DJ
    Biochem Biophys Res Commun; 1996 Jul; 224(3):863-9. PubMed ID: 8713136
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Aminoacyl adenylate substrate analogues for the inhibition of adenylation domains of nonribosomal peptide synthetases.
    Finking R; Neumüller A; Solsbacher J; Konz D; Kretzschmar G; Schweitzer M; Krumm T; Marahiel MA
    Chembiochem; 2003 Sep; 4(9):903-6. PubMed ID: 12964169
    [No Abstract]   [Full Text] [Related]  

  • 14. Synthesis of glutaminyl adenylate analogues that are inhibitors of glutaminyl-tRNA synthetase.
    Bernier S; Dubois DY; Therrien M; Lapointe J; Chênevert R
    Bioorg Med Chem Lett; 2000 Nov; 10(21):2441-4. PubMed ID: 11078196
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Methods to assay inhibitors of tRNA synthetase activity.
    Beyer D; Kroll HP; Brötz-Oesterhelt H
    Methods Mol Med; 2008; 142():53-61. PubMed ID: 18437305
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis of beta-ketophosphonate analogs of glutamyl and glutaminyl adenylate, and selective inhibition of the corresponding bacterial aminoacyl-tRNA synthetases.
    Balg C; Blais SP; Bernier S; Huot JL; Couture M; Lapointe J; Chênevert R
    Bioorg Med Chem; 2007 Jan; 15(1):295-304. PubMed ID: 17049867
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Deoxyribosyl analogues of methionyl and isoleucyl sulfamate adenylates as inhibitors of methionyl-tRNA and isoleucyl-tRNA synthetases.
    Kim SE; Kim SY; Kim S; Kang T; Lee J
    Bioorg Med Chem Lett; 2005 Jul; 15(14):3389-93. PubMed ID: 15951176
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Aminoacyl-tRNA synthetase inhibitors as potent and synergistic immunosuppressants.
    Van de Vijver P; Ostrowski T; Sproat B; Goebels J; Rutgeerts O; Van Aerschot A; Waer M; Herdewijn P
    J Med Chem; 2008 May; 51(10):3020-9. PubMed ID: 18438987
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Reactions of functionalized sulfonamides: application to lowering the lipophilicity of cytosolic phospholipase A2alpha inhibitors.
    Chen L; Wang W; Lee KL; Shen MW; Murphy EA; Zhang W; Xu X; Tam S; Nickerson-Nutter C; Goodwin DG; Clark JD; McKew JC
    J Med Chem; 2009 Feb; 52(4):1156-71. PubMed ID: 19178292
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Aminoacyl-tRNA synthetases and their inhibitors as a novel family of antibiotics.
    Kim S; Lee SW; Choi EC; Choi SY
    Appl Microbiol Biotechnol; 2003 May; 61(4):278-88. PubMed ID: 12743756
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 4.