These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

112 related articles for article (PubMed ID: 12242036)

  • 1. Streptozotocin, an O-GlcNAcase inhibitor, blunts insulin and growth hormone secretion.
    Liu K; Paterson AJ; Konrad RJ; Parlow AF; Jimi S; Roh M; Chin E; Kudlow JE
    Mol Cell Endocrinol; 2002 Aug; 194(1-2):135-46. PubMed ID: 12242036
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Streptozotocin-induced beta-cell death is independent of its inhibition of O-GlcNAcase in pancreatic Min6 cells.
    Gao Y; Parker GJ; Hart GW
    Arch Biochem Biophys; 2000 Nov; 383(2):296-302. PubMed ID: 11185566
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Glucose stimulates protein modification by O-linked GlcNAc in pancreatic beta cells: linkage of O-linked GlcNAc to beta cell death.
    Liu K; Paterson AJ; Chin E; Kudlow JE
    Proc Natl Acad Sci U S A; 2000 Mar; 97(6):2820-5. PubMed ID: 10717000
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Elevated O-linked N-acetylglucosamine metabolism in pancreatic beta-cells.
    Hanover JA; Lai Z; Lee G; Lubas WA; Sato SM
    Arch Biochem Biophys; 1999 Feb; 362(1):38-45. PubMed ID: 9917327
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The potential mechanism of the diabetogenic action of streptozotocin: inhibition of pancreatic beta-cell O-GlcNAc-selective N-acetyl-beta-D-glucosaminidase.
    Konrad RJ; Mikolaenko I; Tolar JF; Liu K; Kudlow JE
    Biochem J; 2001 May; 356(Pt 1):31-41. PubMed ID: 11336633
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Cytosolic O-GlcNAc accumulation is not involved in beta-cell death in HIT-T15 or Min6.
    Okuyama R; Yachi M
    Biochem Biophys Res Commun; 2001 Sep; 287(2):366-71. PubMed ID: 11554736
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Glucose and streptozotocin stimulate p135 O-glycosylation in pancreatic islets.
    Konrad RJ; Janowski KM; Kudlow JE
    Biochem Biophys Res Commun; 2000 Jan; 267(1):26-32. PubMed ID: 10623569
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Pleiotropic and age-dependent effects of decreased protein modification by O-linked N-acetylglucosamine on pancreatic β-cell function and vascularization.
    Soesanto Y; Luo B; Parker G; Jones D; Cooksey RC; McClain DA
    J Biol Chem; 2011 Jul; 286(29):26118-26. PubMed ID: 21622566
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Streptozotocin inhibits O-GlcNAcase via the production of a transition state analog.
    Toleman C; Paterson AJ; Shin R; Kudlow JE
    Biochem Biophys Res Commun; 2006 Feb; 340(2):526-34. PubMed ID: 16376298
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Caenorhabditis elegans ortholog of a diabetes susceptibility locus: oga-1 (O-GlcNAcase) knockout impacts O-GlcNAc cycling, metabolism, and dauer.
    Forsythe ME; Love DC; Lazarus BD; Kim EJ; Prinz WA; Ashwell G; Krause MW; Hanover JA
    Proc Natl Acad Sci U S A; 2006 Aug; 103(32):11952-7. PubMed ID: 16882729
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The diabetogenic antibiotic streptozotocin modifies the tryptic digest pattern for peptides of the enzyme O-GlcNAc-selective N-acetyl-beta-d-glucosaminidase that contain amino acid residues essential for enzymatic activity.
    Lee TN; Alborn WE; Knierman MD; Konrad RJ
    Biochem Pharmacol; 2006 Sep; 72(6):710-8. PubMed ID: 16844097
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Elevation of the post-translational modification of proteins by O-linked N-acetylglucosamine leads to deterioration of the glucose-stimulated insulin secretion in the pancreas of diabetic Goto-Kakizaki rats.
    Akimoto Y; Hart GW; Wells L; Vosseller K; Yamamoto K; Munetomo E; Ohara-Imaizumi M; Nishiwaki C; Nagamatsu S; Hirano H; Kawakami H
    Glycobiology; 2007 Feb; 17(2):127-40. PubMed ID: 17095531
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Accumulation of protein O-GlcNAc modification inhibits proteasomes in the brain and coincides with neuronal apoptosis in brain areas with high O-GlcNAc metabolism.
    Liu K; Paterson AJ; Zhang F; McAndrew J; Fukuchi K; Wyss JM; Peng L; Hu Y; Kudlow JE
    J Neurochem; 2004 May; 89(4):1044-55. PubMed ID: 15140202
    [TBL] [Abstract][Full Text] [Related]  

  • 14. O-GlcNAcase uses substrate-assisted catalysis: kinetic analysis and development of highly selective mechanism-inspired inhibitors.
    Macauley MS; Whitworth GE; Debowski AW; Chin D; Vocadlo DJ
    J Biol Chem; 2005 Jul; 280(27):25313-22. PubMed ID: 15795231
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Chemical dissection of the link between streptozotocin, O-GlcNAc, and pancreatic cell death.
    Pathak S; Dorfmueller HC; Borodkin VS; van Aalten DM
    Chem Biol; 2008 Aug; 15(8):799-807. PubMed ID: 18721751
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Elevated expression of O-GlcNAc-modified proteins and O-GlcNAc transferase in corneas of diabetic Goto-Kakizaki rats.
    Akimoto Y; Kawakami H; Yamamoto K; Munetomo E; Hida T; Hirano H
    Invest Ophthalmol Vis Sci; 2003 Sep; 44(9):3802-9. PubMed ID: 12939295
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Differential insulin secretory activity in rat pancreatic islets and HIT cells.
    Tanigawa K; Kashiwada J; Tamura K; Kawaguchi M; Seino Y; Kato Y
    Diabetes Res; 1994; 26(1):1-11. PubMed ID: 7664532
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Transgenic mice expressing Shb adaptor protein under the control of rat insulin promoter exhibit altered viability of pancreatic islet cells.
    Welsh M; Christmansson L; Karlsson T; Sandler S; Welsh N
    Mol Med; 1999 Mar; 5(3):169-80. PubMed ID: 10404514
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A modified method of islet isolation preserves the ability of pancreatic islets to increase protein O-glycosylation in response to glucose and streptozotocin.
    Konrad RJ; Liu K; Kudlow JE
    Arch Biochem Biophys; 2000 Sep; 381(1):92-8. PubMed ID: 11019824
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Streptozotocin (STZ) mediates acute upregulation of serum and pancreatic osteopontin (OPN): a novel islet-protective effect of OPN through inhibition of STZ-induced nitric oxide production.
    Katakam AK; Chipitsyna G; Gong Q; Vancha AR; Gabbeta J; Arafat HA
    J Endocrinol; 2005 Nov; 187(2):237-47. PubMed ID: 16293771
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.