BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

171 related articles for article (PubMed ID: 12244155)

  • 1. IL-12 provides proliferation and survival signals to murine CD4+ T cells through phosphatidylinositol 3-kinase/Akt signaling pathway.
    Yoo JK; Cho JH; Lee SW; Sung YC
    J Immunol; 2002 Oct; 169(7):3637-43. PubMed ID: 12244155
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The forkhead transcription factor FoxO regulates transcription of p27Kip1 and Bim in response to IL-2.
    Stahl M; Dijkers PF; Kops GJ; Lens SM; Coffer PJ; Burgering BM; Medema RH
    J Immunol; 2002 May; 168(10):5024-31. PubMed ID: 11994454
    [TBL] [Abstract][Full Text] [Related]  

  • 3. CD28 costimulation mediates down-regulation of p27kip1 and cell cycle progression by activation of the PI3K/PKB signaling pathway in primary human T cells.
    Appleman LJ; van Puijenbroek AA; Shu KM; Nadler LM; Boussiotis VA
    J Immunol; 2002 Mar; 168(6):2729-36. PubMed ID: 11884439
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A co-stimulatory molecule on activated T cells, H4/ICOS, delivers specific signals in T(h) cells and regulates their responses.
    Arimura Y; Kato H; Dianzani U; Okamoto T; Kamekura S; Buonfiglio D; Miyoshi-Akiyama T; Uchiyama T; Yagi J
    Int Immunol; 2002 Jun; 14(6):555-66. PubMed ID: 12039907
    [TBL] [Abstract][Full Text] [Related]  

  • 5. IL-2 and related cytokines can promote T cell survival by activating AKT.
    Kelly E; Won A; Refaeli Y; Van Parijs L
    J Immunol; 2002 Jan; 168(2):597-603. PubMed ID: 11777951
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Phagocytosis of apoptotic cells by macrophages induces novel signaling events leading to cytokine-independent survival and inhibition of proliferation: activation of Akt and inhibition of extracellular signal-regulated kinases 1 and 2.
    Reddy SM; Hsiao KH; Abernethy VE; Fan H; Longacre A; Lieberthal W; Rauch J; Koh JS; Levine JS
    J Immunol; 2002 Jul; 169(2):702-13. PubMed ID: 12097372
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Interleukin-7 promotes the survival of human CD4+ effector/memory T cells by up-regulating Bcl-2 proteins and activating the JAK/STAT signalling pathway.
    Chetoui N; Boisvert M; Gendron S; Aoudjit F
    Immunology; 2010 Jul; 130(3):418-26. PubMed ID: 20465565
    [TBL] [Abstract][Full Text] [Related]  

  • 8. T cell leukemia-1 modulates TCR signal strength and IFN-gamma levels through phosphatidylinositol 3-kinase and protein kinase C pathway activation.
    Hoyer KK; Herling M; Bagrintseva K; Dawson DW; French SW; Renard M; Weinger JG; Jones D; Teitell MA
    J Immunol; 2005 Jul; 175(2):864-73. PubMed ID: 16002684
    [TBL] [Abstract][Full Text] [Related]  

  • 9. IL-7 inhibits dexamethasone-induced apoptosis via Akt/PKB in mature, peripheral T cells.
    Sade H; Sarin A
    Eur J Immunol; 2003 Apr; 33(4):913-9. PubMed ID: 12672057
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Phosphatidylinositol 3-kinase and NF-kappa B/Rel are at the divergence of CD40-mediated proliferation and survival pathways.
    Andjelic S; Hsia C; Suzuki H; Kadowaki T; Koyasu S; Liou HC
    J Immunol; 2000 Oct; 165(7):3860-7. PubMed ID: 11034392
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The phosphatidylinositol 3-kinase/AKT signal transduction pathway plays a critical role in the expression of p21WAF1/CIP1/SDI1 induced by cisplatin and paclitaxel.
    Mitsuuchi Y; Johnson SW; Selvakumaran M; Williams SJ; Hamilton TC; Testa JR
    Cancer Res; 2000 Oct; 60(19):5390-4. PubMed ID: 11034077
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Distinct IL-2 receptor signaling pattern in CD4+CD25+ regulatory T cells.
    Bensinger SJ; Walsh PT; Zhang J; Carroll M; Parsons R; Rathmell JC; Thompson CB; Burchill MA; Farrar MA; Turka LA
    J Immunol; 2004 May; 172(9):5287-96. PubMed ID: 15100267
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Diacylglycerol kinase inhibition prevents IL-2-induced G1 to S transition through a phosphatidylinositol-3 kinase-independent mechanism.
    Flores I; Jones DR; Ciprés A; Díaz-Flores E; Sanjuan MA; Mérida I
    J Immunol; 1999 Jul; 163(2):708-14. PubMed ID: 10395661
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Defective cell cycle induction by IL-2 in naive T-cells antigen stimulated in the presence of refractory T-lymphocytes.
    Inaba H; Geiger TL
    Int Immunol; 2006 Jul; 18(7):1043-54. PubMed ID: 16702166
    [TBL] [Abstract][Full Text] [Related]  

  • 15. CD28-dependent activation of protein kinase B/Akt blocks Fas-mediated apoptosis by preventing death-inducing signaling complex assembly.
    Jones RG; Elford AR; Parsons MJ; Wu L; Krawczyk CM; Yeh WC; Hakem R; Rottapel R; Woodgett JR; Ohashi PS
    J Exp Med; 2002 Aug; 196(3):335-48. PubMed ID: 12163562
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Cytokine-mediated inhibition of apoptosis in non-transformed T cells and neutrophils can be dissociated from protein kinase B activation.
    Scheel-Toellner D; Wang K; Henriquez NV; Webb PR; Craddock R; Pilling D; Akbar AN; Salmon M; Lord JM
    Eur J Immunol; 2002 Feb; 32(2):486-93. PubMed ID: 11828365
    [TBL] [Abstract][Full Text] [Related]  

  • 17. IL-7 activates the phosphatidylinositol 3-kinase/AKT pathway in normal human thymocytes but not normal human B cell precursors.
    Johnson SE; Shah N; Bajer AA; LeBien TW
    J Immunol; 2008 Jun; 180(12):8109-17. PubMed ID: 18523275
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Role of the phosphatidylinositol 3-kinase/Akt and mTOR/P70S6-kinase pathways in the proliferation and apoptosis in multiple myeloma.
    Pene F; Claessens YE; Muller O; Viguié F; Mayeux P; Dreyfus F; Lacombe C; Bouscary D
    Oncogene; 2002 Sep; 21(43):6587-97. PubMed ID: 12242656
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Protein kinase C-theta-mediated signals enhance CD4+ T cell survival by up-regulating Bcl-xL.
    Manicassamy S; Gupta S; Huang Z; Sun Z
    J Immunol; 2006 Jun; 176(11):6709-16. PubMed ID: 16709830
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Requirement for the PI3K/Akt pathway in MEK1-mediated growth and prevention of apoptosis: identification of an Achilles heel in leukemia.
    Blalock WL; Navolanic PM; Steelman LS; Shelton JG; Moye PW; Lee JT; Franklin RA; Mirza A; McMahon M; White MK; McCubrey JA
    Leukemia; 2003 Jun; 17(6):1058-67. PubMed ID: 12764369
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.