BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

551 related articles for article (PubMed ID: 12244302)

  • 1. PKB/Akt phosphorylates p27, impairs nuclear import of p27 and opposes p27-mediated G1 arrest.
    Liang J; Zubovitz J; Petrocelli T; Kotchetkov R; Connor MK; Han K; Lee JH; Ciarallo S; Catzavelos C; Beniston R; Franssen E; Slingerland JM
    Nat Med; 2002 Oct; 8(10):1153-60. PubMed ID: 12244302
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Cytoplasmic relocalization and inhibition of the cyclin-dependent kinase inhibitor p27(Kip1) by PKB/Akt-mediated phosphorylation in breast cancer.
    Viglietto G; Motti ML; Bruni P; Melillo RM; D'Alessio A; Califano D; Vinci F; Chiappetta G; Tsichlis P; Bellacosa A; Fusco A; Santoro M
    Nat Med; 2002 Oct; 8(10):1136-44. PubMed ID: 12244303
    [TBL] [Abstract][Full Text] [Related]  

  • 3. ErbB2/neu kinase modulates cellular p27(Kip1) and cyclin D1 through multiple signaling pathways.
    Lenferink AE; Busse D; Flanagan WM; Yakes FM; Arteaga CL
    Cancer Res; 2001 Sep; 61(17):6583-91. PubMed ID: 11522658
    [TBL] [Abstract][Full Text] [Related]  

  • 4. PKB/Akt mediates cell-cycle progression by phosphorylation of p27(Kip1) at threonine 157 and modulation of its cellular localization.
    Shin I; Yakes FM; Rojo F; Shin NY; Bakin AV; Baselga J; Arteaga CL
    Nat Med; 2002 Oct; 8(10):1145-52. PubMed ID: 12244301
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Effects of oncogenic ErbB2 on G1 cell cycle regulators in breast tumour cells.
    Neve RM; Sutterlüty H; Pullen N; Lane HA; Daly JM; Krek W; Hynes NE
    Oncogene; 2000 Mar; 19(13):1647-56. PubMed ID: 10763821
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The phosphoinositide 3-kinase/Akt pathway regulates cell cycle progression of HL60 human leukemia cells through cytoplasmic relocalization of the cyclin-dependent kinase inhibitor p27(Kip1) and control of cyclin D1 expression.
    Cappellini A; Tabellini G; Zweyer M; Bortul R; Tazzari PL; Billi AM; Falà F; Cocco L; Martelli AM
    Leukemia; 2003 Nov; 17(11):2157-67. PubMed ID: 12931221
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Adhesion-regulated G1 cell cycle arrest in epithelial cells requires the downregulation of c-Myc.
    Benaud CM; Dickson RB
    Oncogene; 2001 Jul; 20(33):4554-67. PubMed ID: 11494151
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Cytokine-induced phosphoinositide 3-kinase activity promotes Cdk2 activation in factor-dependent hematopoietic cells.
    Henry MK; Nimbalkar D; Hohl RJ; Quelle FW
    Exp Cell Res; 2004 Sep; 299(1):257-66. PubMed ID: 15302592
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cytoplasmic mislocalization of p27Kip1 protein is associated with constitutive phosphorylation of Akt or protein kinase B and poor prognosis in acute myelogenous leukemia.
    Min YH; Cheong JW; Kim JY; Eom JI; Lee ST; Hahn JS; Ko YW; Lee MH
    Cancer Res; 2004 Aug; 64(15):5225-31. PubMed ID: 15289327
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Disruption of the actin cytoskeleton leads to inhibition of mitogen-induced cyclin E expression, Cdk2 phosphorylation, and nuclear accumulation of the retinoblastoma protein-related p107 protein.
    Reshetnikova G; Barkan R; Popov B; Nikolsky N; Chang LS
    Exp Cell Res; 2000 Aug; 259(1):35-53. PubMed ID: 10942577
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cell cycle-dependent phosphorylation of p27 cyclin-dependent kinase (Cdk) inhibitor by cyclin E/Cdk2.
    Morisaki H; Fujimoto A; Ando A; Nagata Y; Ikeda K; Nakanishi M
    Biochem Biophys Res Commun; 1997 Nov; 240(2):386-90. PubMed ID: 9388487
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Lovastatin mediated G1 arrest in normal and tumor breast cells is through inhibition of CDK2 activity and redistribution of p21 and p27, independent of p53.
    Rao S; Lowe M; Herliczek TW; Keyomarsi K
    Oncogene; 1998 Nov; 17(18):2393-402. PubMed ID: 9811471
    [TBL] [Abstract][Full Text] [Related]  

  • 13. 14-3-3 suppresses the nuclear localization of threonine 157-phosphorylated p27(Kip1).
    Sekimoto T; Fukumoto M; Yoneda Y
    EMBO J; 2004 May; 23(9):1934-42. PubMed ID: 15057270
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Accumulation of a form of p27(Kip1) not associated with Cdk-cyclin complexes in transforming growth factor-beta-arrested Mv1Lu cells.
    Taipale M; Tiihonen E; Heiskanen A; Laiho M
    Exp Cell Res; 2000 Aug; 259(1):107-16. PubMed ID: 10942583
    [TBL] [Abstract][Full Text] [Related]  

  • 15. An adenovirus expressing mutant p27 showed more potent antitumor effects than adenovirus-p27 wild type.
    Park KH; Seol JY; Kim TY; Yoo CG; Kim YW; Han SK; Shim YS; Lee CT
    Cancer Res; 2001 Aug; 61(16):6163-9. PubMed ID: 11507068
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Differential effects of transforming growth factor on cell cycle regulatory molecules in human myeloid leukemia cells.
    Hu X; Zhang X; Zhong Q; Fisher AB; Bryington M; Zuckerman KS
    Oncogene; 2001 Oct; 20(47):6840-50. PubMed ID: 11687963
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Herceptin-induced inhibition of phosphatidylinositol-3 kinase and Akt Is required for antibody-mediated effects on p27, cyclin D1, and antitumor action.
    Yakes FM; Chinratanalab W; Ritter CA; King W; Seelig S; Arteaga CL
    Cancer Res; 2002 Jul; 62(14):4132-41. PubMed ID: 12124352
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Lactoferrin inhibits G1 cyclin-dependent kinases during growth arrest of human breast carcinoma cells.
    Damiens E; El Yazidi I; Mazurier J; Duthille I; Spik G; Boilly-Marer Y
    J Cell Biochem; 1999 Sep; 74(3):486-98. PubMed ID: 10412049
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mutant epidermal growth factor receptor signaling down-regulates p27 through activation of the phosphatidylinositol 3-kinase/Akt pathway in glioblastomas.
    Narita Y; Nagane M; Mishima K; Huang HJ; Furnari FB; Cavenee WK
    Cancer Res; 2002 Nov; 62(22):6764-9. PubMed ID: 12438278
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Reduction of Cdc25A contributes to cyclin E1-Cdk2 inhibition at senescence in human mammary epithelial cells.
    Sandhu C; Donovan J; Bhattacharya N; Stampfer M; Worland P; Slingerland J
    Oncogene; 2000 Nov; 19(47):5314-23. PubMed ID: 11103932
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 28.