140 related articles for article (PubMed ID: 12270168)
1. Novel amide-based inhibitors of inosine 5'-monophosphate dehydrogenase.
Watterson SH; Liu C; Dhar TG; Gu HH; Pitts WJ; Barrish JC; Fleener CA; Rouleau K; Sherbina NZ; Hollenbaugh DL; Iwanowicz EJ
Bioorg Med Chem Lett; 2002 Oct; 12(20):2879-82. PubMed ID: 12270168
[TBL] [Abstract][Full Text] [Related]
2. Novel guanidine-based inhibitors of inosine monophosphate dehydrogenase.
Iwanowicz EJ; Watterson SH; Liu C; Gu HH; Mitt T; Leftheris K; Barrish JC; Fleener CA; Rouleau K; Sherbina NZ; Hollenbaugh DL
Bioorg Med Chem Lett; 2002 Oct; 12(20):2931-4. PubMed ID: 12270177
[TBL] [Abstract][Full Text] [Related]
3. Inhibition of inosine monophosphate dehydrogenase (IMPDH) by the antiviral compound, 2-vinylinosine monophosphate.
Pal S; Bera B; Nair V
Bioorg Med Chem; 2002 Nov; 10(11):3615-8. PubMed ID: 12213477
[TBL] [Abstract][Full Text] [Related]
4. Novel inhibitors of IMPDH: a highly potent and selective quinolone-based series.
Watterson SH; Carlsen M; Dhar TG; Shen Z; Pitts WJ; Guo J; Gu HH; Norris D; Chorba J; Chen P; Cheney D; Witmer M; Fleener CA; Rouleau K; Townsend R; Hollenbaugh DL; Iwanowicz EJ
Bioorg Med Chem Lett; 2003 Feb; 13(3):543-6. PubMed ID: 12565968
[TBL] [Abstract][Full Text] [Related]
5. A survey of cyclic replacements for the central diamide moiety of inhibitors of inosine monophosphate dehydrogenase.
Dhar TG; Liu C; Pitts WJ; Guo J; Watterson SH; Gu H; Fleener CA; Rouleau K; Sherbina NZ; Barrish JC; Hollenbaugh D; Iwanowicz EJ
Bioorg Med Chem Lett; 2002 Nov; 12(21):3125-8. PubMed ID: 12372516
[TBL] [Abstract][Full Text] [Related]
6. Novel diamide-based inhibitors of IMPDH.
Gu HH; Iwanowicz EJ; Guo J; Watterson SH; Shen Z; Pitts WJ; Dhar TG; Fleener CA; Rouleau K; Sherbina NZ; Witmer M; Tredup J; Hollenbaugh D
Bioorg Med Chem Lett; 2002 May; 12(9):1323-6. PubMed ID: 11965381
[TBL] [Abstract][Full Text] [Related]
7. 3-cyanoindole-based inhibitors of inosine monophosphate dehydrogenase: synthesis and initial structure-activity relationships.
Dhar TG; Shen Z; Gu HH; Chen P; Norris D; Watterson SH; Ballentine SK; Fleener CA; Rouleau KA; Barrish JC; Townsend R; Hollenbaugh DL; Iwanowicz EJ
Bioorg Med Chem Lett; 2003 Oct; 13(20):3557-60. PubMed ID: 14505670
[TBL] [Abstract][Full Text] [Related]
8. Synthesis of the inosine 5'-monophosphate dehydrogenase (IMPDH) inhibitors.
Cholewiński G; Iwaszkiewicz-Grześ D; Prejs M; Głowacka A; Dzierzbicka K
J Enzyme Inhib Med Chem; 2015; 30(4):550-63. PubMed ID: 25198892
[TBL] [Abstract][Full Text] [Related]
9. [The determination and clinical application of inosine 5’-monophosphate dehydrogenase activity].
Liu FY; Qiu XY; Jiao Z
Yao Xue Xue Bao; 2016 Nov; 51(11):1666-73. PubMed ID: 29908108
[TBL] [Abstract][Full Text] [Related]
10. Novel indole-based inhibitors of IMPDH: introduction of hydrogen bond acceptors at indole C-3.
Watterson SH; Dhar TG; Ballentine SK; Shen Z; Barrish JC; Cheney D; Fleener CA; Rouleau KA; Townsend R; Hollenbaugh DL; Iwanowicz EJ
Bioorg Med Chem Lett; 2003 Apr; 13(7):1273-6. PubMed ID: 12657262
[TBL] [Abstract][Full Text] [Related]
11. Synthesis and biological activities of 2-functionalized purine nucleosides.
Nair V; Bera B; Kern ER
Nucleosides Nucleotides Nucleic Acids; 2003 Feb; 22(2):115-27. PubMed ID: 12744599
[TBL] [Abstract][Full Text] [Related]
12. Discovery of N-(2,3,5-triazoyl)mycophenolic amide and mycophenolic epoxyketone as novel inhibitors of human IMPDH.
Sunohara K; Mitsuhashi S; Shigetomi K; Ubukata M
Bioorg Med Chem Lett; 2013 Sep; 23(18):5140-4. PubMed ID: 23937979
[TBL] [Abstract][Full Text] [Related]
13. Inosine monophosphate dehydrogenase as a probe in antiviral drug discovery.
Nair V; Shu Q
Antivir Chem Chemother; 2007; 18(5):245-58. PubMed ID: 18046958
[TBL] [Abstract][Full Text] [Related]
14. Low molecular weight indole fragments as IMPDH inhibitors.
Beevers RE; Buckley GM; Davies N; Fraser JL; Galvin FC; Hannah DR; Haughan AF; Jenkins K; Mack SR; Pitt WR; Ratcliffe AJ; Richard MD; Sabin V; Sharpe A; Williams SC
Bioorg Med Chem Lett; 2006 May; 16(9):2535-8. PubMed ID: 16483769
[TBL] [Abstract][Full Text] [Related]
15. The TosMIC approach to 3-(oxazol-5-yl) indoles: application to the synthesis of indole-based IMPDH inhibitors.
Dhar TG; Shen Z; Fleener CA; Rouleau KA; Barrish JC; Hollenbaugh DL; Iwanowicz EJ
Bioorg Med Chem Lett; 2002 Nov; 12(22):3305-8. PubMed ID: 12392738
[TBL] [Abstract][Full Text] [Related]
16. Novel inhibitors of inosine monophosphate dehydrogenase in patent literature of the last decade.
Petrelli R; Vita P; Torquati I; Felczak K; Wilson DJ; Franchetti P; Cappellacci L
Recent Pat Anticancer Drug Discov; 2013 May; 8(2):103-25. PubMed ID: 23016672
[TBL] [Abstract][Full Text] [Related]
17. Quinazolinethiones and quinazolinediones, novel inhibitors of inosine monophosphate dehydrogenase: synthesis and initial structure-activity relationships.
Buckley GM; Davies N; Dyke HJ; Gilbert PJ; Hannah DR; Haughan AF; Hunt CA; Pitt WR; Profit RH; Ray NC; Richard MD; Sharpe A; Taylor AJ; Whitworth JM; Williams SC
Bioorg Med Chem Lett; 2005 Feb; 15(3):751-4. PubMed ID: 15664851
[TBL] [Abstract][Full Text] [Related]
18. IMPDH as a biological probe for RNA antiviral drug discovery: synthesis, enzymology, molecular docking, and antiviral activity of new ribonucleosides with surrogate bases.
Nair V; Ma X; Shu Q; Zhang F; Uchil V; Cherukupalli GR
Nucleosides Nucleotides Nucleic Acids; 2007; 26(6-7):651-4. PubMed ID: 18066873
[TBL] [Abstract][Full Text] [Related]
19. Inhibitors of inosine monophosphate dehydrogenase: probes for antiviral drug discovery.
Story S; Gupta M; Bonsu E; Nair V
Nucleosides Nucleotides Nucleic Acids; 2005; 24(5-7):717-20. PubMed ID: 16248022
[TBL] [Abstract][Full Text] [Related]
20. Novel indole inhibitors of IMPDH from fragments: synthesis and initial structure-activity relationships.
Beevers RE; Buckley GM; Davies N; Fraser JL; Galvin FC; Hannah DR; Haughan AF; Jenkins K; Mack SR; Pitt WR; Ratcliffe AJ; Richard MD; Sabin V; Sharpe A; Williams SC
Bioorg Med Chem Lett; 2006 May; 16(9):2539-42. PubMed ID: 16483773
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
