BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

230 related articles for article (PubMed ID: 12297048)

  • 1. Presenilin couples the paired phosphorylation of beta-catenin independent of axin: implications for beta-catenin activation in tumorigenesis.
    Kang DE; Soriano S; Xia X; Eberhart CG; De Strooper B; Zheng H; Koo EH
    Cell; 2002 Sep; 110(6):751-62. PubMed ID: 12297048
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inhibitory effect of a presenilin 1 mutation on the Wnt signalling pathway by enhancement of beta-catenin phosphorylation.
    Kawamura Y; Kikuchi A; Takada R; Takada S; Sudoh S; Shibamoto S; Yanagisawa K; Komano H
    Eur J Biochem; 2001 May; 268(10):3036-41. PubMed ID: 11358522
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Presenilin 1 negatively regulates beta-catenin/T cell factor/lymphoid enhancer factor-1 signaling independently of beta-amyloid precursor protein and notch processing.
    Soriano S; Kang DE; Fu M; Pestell R; Chevallier N; Zheng H; Koo EH
    J Cell Biol; 2001 Feb; 152(4):785-94. PubMed ID: 11266469
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Wnt-induced dephosphorylation of axin releases beta-catenin from the axin complex.
    Willert K; Shibamoto S; Nusse R
    Genes Dev; 1999 Jul; 13(14):1768-73. PubMed ID: 10421629
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Role of Wnt pathway in medulloblastoma oncogenesis.
    Yokota N; Nishizawa S; Ohta S; Date H; Sugimura H; Namba H; Maekawa M
    Int J Cancer; 2002 Sep; 101(2):198-201. PubMed ID: 12209999
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Phosphorylation and regulation of beta-catenin by casein kinase I epsilon.
    Sakanaka C
    J Biochem; 2002 Nov; 132(5):697-703. PubMed ID: 12417018
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The ankyrin repeat protein Diversin recruits Casein kinase Iepsilon to the beta-catenin degradation complex and acts in both canonical Wnt and Wnt/JNK signaling.
    Schwarz-Romond T; Asbrand C; Bakkers J; Kühl M; Schaeffer HJ; Huelsken J; Behrens J; Hammerschmidt M; Birchmeier W
    Genes Dev; 2002 Aug; 16(16):2073-84. PubMed ID: 12183362
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Substitution of a glycogen synthase kinase-3beta phosphorylation site in presenilin 1 separates presenilin function from beta-catenin signaling.
    Kirschenbaum F; Hsu SC; Cordell B; McCarthy JV
    J Biol Chem; 2001 Mar; 276(10):7366-75. PubMed ID: 11104755
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Regulation of the Wnt signaling pathway by disabled-2 (Dab2).
    Hocevar BA; Mou F; Rennolds JL; Morris SM; Cooper JA; Howe PH
    EMBO J; 2003 Jun; 22(12):3084-94. PubMed ID: 12805222
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Where Notch and Wnt signaling meet. The presenilin hub.
    De Strooper B; Annaert W
    J Cell Biol; 2001 Feb; 152(4):F17-20. PubMed ID: 11266476
    [No Abstract]   [Full Text] [Related]  

  • 11. A GSK3beta phosphorylation site in axin modulates interaction with beta-catenin and Tcf-mediated gene expression.
    Jho Eh; Lomvardas S; Costantini F
    Biochem Biophys Res Commun; 1999 Dec; 266(1):28-35. PubMed ID: 10581160
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Loss of presenilin 1 is associated with enhanced beta-catenin signaling and skin tumorigenesis.
    Xia X; Qian S; Soriano S; Wu Y; Fletcher AM; Wang XJ; Koo EH; Wu X; Zheng H
    Proc Natl Acad Sci U S A; 2001 Sep; 98(19):10863-8. PubMed ID: 11517342
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Domains of axin involved in protein-protein interactions, Wnt pathway inhibition, and intracellular localization.
    Fagotto F; Jho Eh; Zeng L; Kurth T; Joos T; Kaufmann C; Costantini F
    J Cell Biol; 1999 May; 145(4):741-56. PubMed ID: 10330403
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Casein kinase I phosphorylates and destabilizes the beta-catenin degradation complex.
    Gao ZH; Seeling JM; Hill V; Yochum A; Virshup DM
    Proc Natl Acad Sci U S A; 2002 Feb; 99(3):1182-7. PubMed ID: 11818547
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Bridging of beta-catenin and glycogen synthase kinase-3beta by axin and inhibition of beta-catenin-mediated transcription.
    Sakanaka C; Weiss JB; Williams LT
    Proc Natl Acad Sci U S A; 1998 Mar; 95(6):3020-3. PubMed ID: 9501208
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Axin: a master scaffold for multiple signaling pathways.
    Luo W; Lin SC
    Neurosignals; 2004; 13(3):99-113. PubMed ID: 15067197
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Presenilin 1 independently regulates beta-catenin stability and transcriptional activity.
    Killick R; Pollard CC; Asuni AA; Mudher AK; Richardson JC; Rupniak HT; Sheppard PW; Varndell IM; Brion JP; Levey AI; Levy OA; Vestling M; Cowburn R; Lovestone S; Anderton BH
    J Biol Chem; 2001 Dec; 276(51):48554-61. PubMed ID: 11606587
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Axin facilitates Smad3 activation in the transforming growth factor beta signaling pathway.
    Furuhashi M; Yagi K; Yamamoto H; Furukawa Y; Shimada S; Nakamura Y; Kikuchi A; Miyazono K; Kato M
    Mol Cell Biol; 2001 Aug; 21(15):5132-41. PubMed ID: 11438668
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Presenilin 1 facilitates the constitutive turnover of beta-catenin: differential activity of Alzheimer's disease-linked PS1 mutants in the beta-catenin-signaling pathway.
    Kang DE; Soriano S; Frosch MP; Collins T; Naruse S; Sisodia SS; Leibowitz G; Levine F; Koo EH
    J Neurosci; 1999 Jun; 19(11):4229-37. PubMed ID: 10341227
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanism.
    Liu C; Li Y; Semenov M; Han C; Baeg GH; Tan Y; Zhang Z; Lin X; He X
    Cell; 2002 Mar; 108(6):837-47. PubMed ID: 11955436
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.