BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

588 related articles for article (PubMed ID: 12360479)

  • 1. PTEN and TNF-alpha regulation of the intestinal-specific Cdx-2 homeobox gene through a PI3K, PKB/Akt, and NF-kappaB-dependent pathway.
    Kim S; Domon-Dell C; Wang Q; Chung DH; Di Cristofano A; Pandolfi PP; Freund JN; Evers BM
    Gastroenterology; 2002 Oct; 123(4):1163-78. PubMed ID: 12360479
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Down-regulation of the tumor suppressor PTEN by the tumor necrosis factor-alpha/nuclear factor-kappaB (NF-kappaB)-inducing kinase/NF-kappaB pathway is linked to a default IkappaB-alpha autoregulatory loop.
    Kim S; Domon-Dell C; Kang J; Chung DH; Freund JN; Evers BM
    J Biol Chem; 2004 Feb; 279(6):4285-91. PubMed ID: 14623898
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Her-2/neu overexpression induces NF-kappaB via a PI3-kinase/Akt pathway involving calpain-mediated degradation of IkappaB-alpha that can be inhibited by the tumor suppressor PTEN.
    Pianetti S; Arsura M; Romieu-Mourez R; Coffey RJ; Sonenshein GE
    Oncogene; 2001 Mar; 20(11):1287-99. PubMed ID: 11313873
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Inhibition of nuclear factor kappaB and phosphatidylinositol 3-kinase/Akt is essential for massive hepatocyte apoptosis induced by tumor necrosis factor alpha in mice.
    Imose M; Nagaki M; Naiki T; Osawa Y; Brenner DA; Asano T; Hayashi H; Kato T; Moriwaki H
    Liver Int; 2003 Oct; 23(5):386-96. PubMed ID: 14708901
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inhibition of the phosphatidylinositol 3-kinase pathway contributes to HT29 and Caco-2 intestinal cell differentiation.
    Wang Q; Wang X; Hernandez A; Kim S; Evers BM
    Gastroenterology; 2001 May; 120(6):1381-92. PubMed ID: 11313308
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Requirement of phosphoinositide 3-kinase and Akt for interferon-beta-mediated induction of the beta-R1 (SCYB11) gene.
    Rani MR; Hibbert L; Sizemore N; Stark GR; Ransohoff RM
    J Biol Chem; 2002 Oct; 277(41):38456-61. PubMed ID: 12169689
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Preferential killing of PTEN-null myelomas by PI3K inhibitors through Akt pathway.
    Zhang J; Choi Y; Mavromatis B; Lichtenstein A; Li W
    Oncogene; 2003 Sep; 22(40):6289-95. PubMed ID: 13679867
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Akt regulates COX-2 mRNA and protein expression in mutated-PTEN human endometrial cancer cells.
    St-Germain ME; Gagnon V; Mathieu I; Parent S; Asselin E
    Int J Oncol; 2004 May; 24(5):1311-24. PubMed ID: 15067356
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The PI 3-kinase/Akt signaling pathway is activated due to aberrant Pten expression and targets transcription factors NF-kappaB and c-Myc in pancreatic cancer cells.
    Asano T; Yao Y; Zhu J; Li D; Abbruzzese JL; Reddy SA
    Oncogene; 2004 Nov; 23(53):8571-80. PubMed ID: 15467756
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Suppression of PTEN expression by NF-kappa B prevents apoptosis.
    Vasudevan KM; Gurumurthy S; Rangnekar VM
    Mol Cell Biol; 2004 Feb; 24(3):1007-21. PubMed ID: 14729949
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Dual regulation of MMP-2 expression by the type 1 insulin-like growth factor receptor: the phosphatidylinositol 3-kinase/Akt and Raf/ERK pathways transmit opposing signals.
    Zhang D; Bar-Eli M; Meloche S; Brodt P
    J Biol Chem; 2004 May; 279(19):19683-90. PubMed ID: 14993222
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Type 1 insulin-like growth factor regulates MT1-MMP synthesis and tumor invasion via PI 3-kinase/Akt signaling.
    Zhang D; Brodt P
    Oncogene; 2003 Feb; 22(7):974-82. PubMed ID: 12592384
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Phosphoinositide 3-kinase/Akt involvement in arsenic trioxide resistance of human leukemia cells.
    Tabellini G; Cappellini A; Tazzari PL; FalĂ  F; Billi AM; Manzoli L; Cocco L; Martelli AM
    J Cell Physiol; 2005 Feb; 202(2):623-34. PubMed ID: 15316930
    [TBL] [Abstract][Full Text] [Related]  

  • 14. PTEN suppresses breast cancer cell growth by phosphatase activity-dependent G1 arrest followed by cell death.
    Weng LP; Smith WM; Dahia PL; Ziebold U; Gil E; Lees JA; Eng C
    Cancer Res; 1999 Nov; 59(22):5808-14. PubMed ID: 10582703
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Loss of tumor suppressor p53 decreases PTEN expression and enhances signaling pathways leading to activation of activator protein 1 and nuclear factor kappaB induced by UV radiation.
    Wang J; Ouyang W; Li J; Wei L; Ma Q; Zhang Z; Tong Q; He J; Huang C
    Cancer Res; 2005 Aug; 65(15):6601-11. PubMed ID: 16061640
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Regulation of TRAIL expression by the phosphatidylinositol 3-kinase/Akt/GSK-3 pathway in human colon cancer cells.
    Wang Q; Wang X; Hernandez A; Hellmich MR; Gatalica Z; Evers BM
    J Biol Chem; 2002 Sep; 277(39):36602-10. PubMed ID: 12140294
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Modulation of hypoxia-inducible factor 1alpha expression by the epidermal growth factor/phosphatidylinositol 3-kinase/PTEN/AKT/FRAP pathway in human prostate cancer cells: implications for tumor angiogenesis and therapeutics.
    Zhong H; Chiles K; Feldser D; Laughner E; Hanrahan C; Georgescu MM; Simons JW; Semenza GL
    Cancer Res; 2000 Mar; 60(6):1541-5. PubMed ID: 10749120
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Insulin-like growth factor-I inhibits transcriptional responses of transforming growth factor-beta by phosphatidylinositol 3-kinase/Akt-dependent suppression of the activation of Smad3 but not Smad2.
    Song K; Cornelius SC; Reiss M; Danielpour D
    J Biol Chem; 2003 Oct; 278(40):38342-51. PubMed ID: 12876289
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Role of the phosphatidylinositol 3'-kinase/PTEN/Akt kinase pathway in tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in non-small cell lung cancer cells.
    Kandasamy K; Srivastava RK
    Cancer Res; 2002 Sep; 62(17):4929-37. PubMed ID: 12208743
    [TBL] [Abstract][Full Text] [Related]  

  • 20. TNF-alpha activates MUC2 transcription via NF-kappaB but inhibits via JNK activation.
    Ahn DH; Crawley SC; Hokari R; Kato S; Yang SC; Li JD; Kim YS
    Cell Physiol Biochem; 2005; 15(1-4):29-40. PubMed ID: 15665513
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 30.