BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

250 related articles for article (PubMed ID: 12361980)

  • 1. Functional evidence for the mediation of diabetogenic T cell responses by HLA-A2.1 MHC class I molecules through transgenic expression in NOD mice.
    Marron MP; Graser RT; Chapman HD; Serreze DV
    Proc Natl Acad Sci U S A; 2002 Oct; 99(21):13753-8. PubMed ID: 12361980
    [TBL] [Abstract][Full Text] [Related]  

  • 2. "Humanized" HLA transgenic NOD mice to identify pancreatic beta cell autoantigens of potential clinical relevance to type 1 diabetes.
    Serreze DV; Marron MP; Dilorenzo TP
    Ann N Y Acad Sci; 2007 Apr; 1103():103-11. PubMed ID: 17376821
    [TBL] [Abstract][Full Text] [Related]  

  • 3. HLA-A*0201-restricted T cells from humanized NOD mice recognize autoantigens of potential clinical relevance to type 1 diabetes.
    Takaki T; Marron MP; Mathews CE; Guttmann ST; Bottino R; Trucco M; DiLorenzo TP; Serreze DV
    J Immunol; 2006 Mar; 176(5):3257-65. PubMed ID: 16493087
    [TBL] [Abstract][Full Text] [Related]  

  • 4. MHC class II molecules play a role in the selection of autoreactive class I-restricted CD8 T cells that are essential contributors to type 1 diabetes development in nonobese diabetic mice.
    Serreze DV; Holl TM; Marron MP; Graser RT; Johnson EA; Choisy-Rossi C; Slattery RM; Lieberman SM; DiLorenzo TP
    J Immunol; 2004 Jan; 172(2):871-9. PubMed ID: 14707058
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Thymic and postthymic regulation of diabetogenic CD8 T cell development in TCR transgenic nonobese diabetic (NOD) mice.
    Kanagawa O; Shimizu J; Vaupel BA
    J Immunol; 2000 May; 164(10):5466-73. PubMed ID: 10799914
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Equivalent specificity of peripheral blood and islet-infiltrating CD8+ T lymphocytes in spontaneously diabetic HLA-A2 transgenic NOD mice.
    Enée E; Martinuzzi E; Blancou P; Bach JM; Mallone R; van Endert P
    J Immunol; 2008 Apr; 180(8):5430-8. PubMed ID: 18390725
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Improved Murine MHC-Deficient HLA Transgenic NOD Mouse Models for Type 1 Diabetes Therapy Development.
    Racine JJ; Stewart I; Ratiu J; Christianson G; Lowell E; Helm K; Allocco J; Maser RS; Chen YG; Lutz CM; Roopenian D; Schloss J; DiLorenzo TP; Serreze DV
    Diabetes; 2018 May; 67(5):923-935. PubMed ID: 29472249
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The good turned ugly: immunopathogenic basis for diabetogenic CD8+ T cells in NOD mice.
    DiLorenzo TP; Serreze DV
    Immunol Rev; 2005 Apr; 204():250-63. PubMed ID: 15790363
    [TBL] [Abstract][Full Text] [Related]  

  • 9. An HLA-Transgenic Mouse Model of Type 1 Diabetes That Incorporates the Reduced but Not Abolished Thymic Insulin Expression Seen in Patients.
    Babad J; Ali R; Schloss J; DiLorenzo TP
    J Diabetes Res; 2016; 2016():7959060. PubMed ID: 26824049
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Identification of a CD8 T cell that can independently mediate autoimmune diabetes development in the complete absence of CD4 T cell helper functions.
    Graser RT; DiLorenzo TP; Wang F; Christianson GJ; Chapman HD; Roopenian DC; Nathenson SG; Serreze DV
    J Immunol; 2000 Apr; 164(7):3913-8. PubMed ID: 10725754
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Islet-specific CTL cloned from a type 1 diabetes patient cause beta-cell destruction after engraftment into HLA-A2 transgenic NOD/scid/IL2RG null mice.
    Unger WW; Pearson T; Abreu JR; Laban S; van der Slik AR; der Kracht SM; Kester MG; Serreze DV; Shultz LD; Griffioen M; Drijfhout JW; Greiner DL; Roep BO
    PLoS One; 2012; 7(11):e49213. PubMed ID: 23155466
    [TBL] [Abstract][Full Text] [Related]  

  • 12. HLA-B*39:06 Efficiently Mediates Type 1 Diabetes in a Mouse Model Incorporating Reduced Thymic Insulin Expression.
    Schloss J; Ali R; Racine JJ; Chapman HD; Serreze DV; DiLorenzo TP
    J Immunol; 2018 May; 200(10):3353-3363. PubMed ID: 29632144
    [TBL] [Abstract][Full Text] [Related]  

  • 13. HLA-A2-matched peripheral blood mononuclear cells from type 1 diabetic patients, but not nondiabetic donors, transfer insulitis to NOD-scid/γc(null)/HLA-A2 transgenic mice concurrent with the expansion of islet-specific CD8+ T cells.
    Whitfield-Larry F; Young EF; Talmage G; Fudge E; Azam A; Patel S; Largay J; Byrd W; Buse J; Calikoglu AS; Shultz LD; Frelinger JA
    Diabetes; 2011 Jun; 60(6):1726-33. PubMed ID: 21521873
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Prevention of "Humanized" diabetogenic CD8 T-cell responses in HLA-transgenic NOD mice by a multipeptide coupled-cell approach.
    Niens M; Grier AE; Marron M; Kay TW; Greiner DL; Serreze DV
    Diabetes; 2011 Apr; 60(4):1229-36. PubMed ID: 21346176
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Beta cells cannot directly prime diabetogenic CD8 T cells in nonobese diabetic mice.
    de Jersey J; Snelgrove SL; Palmer SE; Teteris SA; Mullbacher A; Miller JF; Slattery RM
    Proc Natl Acad Sci U S A; 2007 Jan; 104(4):1295-300. PubMed ID: 17229843
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Bridging Mice to Men: Using HLA Transgenic Mice to Enhance the Future Prediction and Prevention of Autoimmune Type 1 Diabetes in Humans.
    Serreze DV; Niens M; Kulik J; DiLorenzo TP
    Methods Mol Biol; 2016; 1438():137-51. PubMed ID: 27150089
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Pancreatic infiltration but not diabetes occurs in the relative absence of MHC class II-restricted CD4 T cells: studies using NOD/CIITA-deficient mice.
    Mora C; Wong FS; Chang CH; Flavell RA
    J Immunol; 1999 Apr; 162(8):4576-88. PubMed ID: 10201997
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Generation of β cell-specific human cytotoxic T cells by lentiviral transduction and their survival in immunodeficient human leucocyte antigen-transgenic mice.
    Babad J; Mukherjee G; Follenzi A; Ali R; Roep BO; Shultz LD; Santamaria P; Yang OO; Goldstein H; Greiner DL; DiLorenzo TP
    Clin Exp Immunol; 2015 Mar; 179(3):398-413. PubMed ID: 25302633
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Initiation of autoimmune diabetes in NOD/Lt mice is MHC class I-dependent.
    Serreze DV; Chapman HD; Varnum DS; Gerling I; Leiter EH; Shultz LD
    J Immunol; 1997 Apr; 158(8):3978-86. PubMed ID: 9103469
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Beyond HLA-A*0201: new HLA-transgenic nonobese diabetic mouse models of type 1 diabetes identify the insulin C-peptide as a rich source of CD8+ T cell epitopes.
    Antal Z; Baker JC; Smith C; Jarchum I; Babad J; Mukherjee G; Yang Y; Sidney J; Sette A; Santamaria P; DiLorenzo TP
    J Immunol; 2012 Jun; 188(11):5766-75. PubMed ID: 22539795
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.