691 related articles for article (PubMed ID: 12362358)
1. Drug design strategies for targeting G-protein-coupled receptors.
Klabunde T; Hessler G
Chembiochem; 2002 Oct; 3(10):928-44. PubMed ID: 12362358
[TBL] [Abstract][Full Text] [Related]
2. Strategies for designing GPCR-focused libraries and screening sets.
Jimonet P; Jäger R
Curr Opin Drug Discov Devel; 2004 May; 7(3):325-33. PubMed ID: 15216936
[TBL] [Abstract][Full Text] [Related]
3. The 7 TM G-protein-coupled receptor target family.
Jacoby E; Bouhelal R; Gerspacher M; Seuwen K
ChemMedChem; 2006 Aug; 1(8):761-82. PubMed ID: 16902930
[TBL] [Abstract][Full Text] [Related]
4. Peptide interactions with G-protein coupled receptors.
Marshall GR
Biopolymers; 2001; 60(3):246-77. PubMed ID: 11774230
[TBL] [Abstract][Full Text] [Related]
5. G-protein-coupled receptor-focused drug discovery using a target class platform approach.
Heilker R; Wolff M; Tautermann CS; Bieler M
Drug Discov Today; 2009 Mar; 14(5-6):231-40. PubMed ID: 19121411
[TBL] [Abstract][Full Text] [Related]
6. Protein-based virtual screening of chemical databases. II. Are homology models of G-Protein Coupled Receptors suitable targets?
Bissantz C; Bernard P; Hibert M; Rognan D
Proteins; 2003 Jan; 50(1):5-25. PubMed ID: 12471595
[TBL] [Abstract][Full Text] [Related]
7. Virtual screening of biogenic amine-binding G-protein coupled receptors: comparative evaluation of protein- and ligand-based virtual screening protocols.
Evers A; Hessler G; Matter H; Klabunde T
J Med Chem; 2005 Aug; 48(17):5448-65. PubMed ID: 16107144
[TBL] [Abstract][Full Text] [Related]
8. Recognition of privileged structures by G-protein coupled receptors.
Bondensgaard K; Ankersen M; Thøgersen H; Hansen BS; Wulff BS; Bywater RP
J Med Chem; 2004 Feb; 47(4):888-99. PubMed ID: 14761190
[TBL] [Abstract][Full Text] [Related]
9. Sequence-derived three-dimensional pharmacophore models for G-protein-coupled receptors and their application in virtual screening.
Klabunde T; Giegerich C; Evers A
J Med Chem; 2009 May; 52(9):2923-32. PubMed ID: 19374402
[TBL] [Abstract][Full Text] [Related]
10. PREDICT modeling and in-silico screening for G-protein coupled receptors.
Shacham S; Marantz Y; Bar-Haim S; Kalid O; Warshaviak D; Avisar N; Inbal B; Heifetz A; Fichman M; Topf M; Naor Z; Noiman S; Becker OM
Proteins; 2004 Oct; 57(1):51-86. PubMed ID: 15326594
[TBL] [Abstract][Full Text] [Related]
11. Structural basis for ligand binding and specificity in adrenergic receptors: implications for GPCR-targeted drug discovery.
Huber T; Menon S; Sakmar TP
Biochemistry; 2008 Oct; 47(42):11013-23. PubMed ID: 18821775
[TBL] [Abstract][Full Text] [Related]
12. Molecular mechanisms of ligand binding, signaling, and regulation within the superfamily of G-protein-coupled receptors: molecular modeling and mutagenesis approaches to receptor structure and function.
Kristiansen K
Pharmacol Ther; 2004 Jul; 103(1):21-80. PubMed ID: 15251227
[TBL] [Abstract][Full Text] [Related]
13. Agonist-induced conformational changes in bovine rhodopsin: insight into activation of G-protein-coupled receptors.
Bhattacharya S; Hall SE; Vaidehi N
J Mol Biol; 2008 Oct; 382(2):539-55. PubMed ID: 18638482
[TBL] [Abstract][Full Text] [Related]
14. Structural diversity of G protein-coupled receptors and significance for drug discovery.
Lagerström MC; Schiöth HB
Nat Rev Drug Discov; 2008 Apr; 7(4):339-57. PubMed ID: 18382464
[TBL] [Abstract][Full Text] [Related]
15. G-protein-coupled receptor affinity prediction based on the use of a profiling dataset: QSAR design, synthesis, and experimental validation.
Rolland C; Gozalbes R; Nicolaï E; Paugam MF; Coussy L; Barbosa F; Horvath D; Revah F
J Med Chem; 2005 Oct; 48(21):6563-74. PubMed ID: 16220973
[TBL] [Abstract][Full Text] [Related]
16. Discovery of novel chemotypes to a G-protein-coupled receptor through ligand-steered homology modeling and structure-based virtual screening.
Cavasotto CN; Orry AJ; Murgolo NJ; Czarniecki MF; Kocsi SA; Hawes BE; O'Neill KA; Hine H; Burton MS; Voigt JH; Abagyan RA; Bayne ML; Monsma FJ
J Med Chem; 2008 Feb; 51(3):581-8. PubMed ID: 18198821
[TBL] [Abstract][Full Text] [Related]
17. GLIDA: GPCR-ligand database for chemical genomic drug discovery.
Okuno Y; Yang J; Taneishi K; Yabuuchi H; Tsujimoto G
Nucleic Acids Res; 2006 Jan; 34(Database issue):D673-7. PubMed ID: 16381956
[TBL] [Abstract][Full Text] [Related]
18. Molecular modelling studies on G protein-coupled receptors: from sequence to structure?
van Neuren AS; Müller G; Klebe G; Moroder L
J Recept Signal Transduct Res; 1999; 19(1-4):341-53. PubMed ID: 10071769
[TBL] [Abstract][Full Text] [Related]
19. Modeling the 3D structure of GPCRs: advances and application to drug discovery.
Becker OM; Shacham S; Marantz Y; Noiman S
Curr Opin Drug Discov Devel; 2003 May; 6(3):353-61. PubMed ID: 12833668
[TBL] [Abstract][Full Text] [Related]
20. Structure-based identification of binding sites, native ligands and potential inhibitors for G-protein coupled receptors.
Cavasotto CN; Orry AJ; Abagyan RA
Proteins; 2003 May; 51(3):423-33. PubMed ID: 12696053
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]