141 related articles for article (PubMed ID: 12368098)
1. Inhibition of HhaI DNA (Cytosine-C5) methyltransferase by oligodeoxyribonucleotides containing 5-aza-2'-deoxycytidine: examination of the intertwined roles of co-factor, target, transition state structure and enzyme conformation.
Brank AS; Eritja R; Garcia RG; Marquez VE; Christman JK
J Mol Biol; 2002 Oct; 323(1):53-67. PubMed ID: 12368098
[TBL] [Abstract][Full Text] [Related]
2. Mechanism of inhibition of DNA (cytosine C5)-methyltransferases by oligodeoxyribonucleotides containing 5,6-dihydro-5-azacytosine.
Sheikhnejad G; Brank A; Christman JK; Goddard A; Alvarez E; Ford H; Marquez VE; Marasco CJ; Sufrin JR; O'gara M; Cheng X
J Mol Biol; 1999 Feb; 285(5):2021-34. PubMed ID: 9925782
[TBL] [Abstract][Full Text] [Related]
3. A 7-Deazaadenosylaziridine Cofactor for Sequence-Specific Labeling of DNA by the DNA Cytosine-C5 Methyltransferase M.HhaI.
Kunkel F; Lurz R; Weinhold E
Molecules; 2015 Nov; 20(11):20805-22. PubMed ID: 26610450
[TBL] [Abstract][Full Text] [Related]
4. The mechanism of DNA cytosine-5 methylation. Kinetic and mutational dissection of Hhai methyltransferase.
Vilkaitis G; Merkiene E; Serva S; Weinhold E; Klimasauskas S
J Biol Chem; 2001 Jun; 276(24):20924-34. PubMed ID: 11283006
[TBL] [Abstract][Full Text] [Related]
5. DNA containing 4'-thio-2'-deoxycytidine inhibits methylation by HhaI methyltransferase.
Kumar S; Horton JR; Jones GD; Walker RT; Roberts RJ; Cheng X
Nucleic Acids Res; 1997 Jul; 25(14):2773-83. PubMed ID: 9207024
[TBL] [Abstract][Full Text] [Related]
6. Structure of a binary complex of HhaI methyltransferase with S-adenosyl-L-methionine formed in the presence of a short non-specific DNA oligonucleotide.
O'Gara M; Zhang X; Roberts RJ; Cheng X
J Mol Biol; 1999 Mar; 287(2):201-9. PubMed ID: 10080885
[TBL] [Abstract][Full Text] [Related]
7. Enzymatic C5-cytosine methylation of DNA: mechanistic implications of new crystal structures for HhaL methyltransferase-DNA-AdoHcy complexes.
O'Gara M; Klimasauskas S; Roberts RJ; Cheng X
J Mol Biol; 1996 Sep; 261(5):634-45. PubMed ID: 8800212
[TBL] [Abstract][Full Text] [Related]
8. DNA (Cytosine-C5) methyltransferase inhibition by oligodeoxyribonucleotides containing 2-(1H)-pyrimidinone (zebularine aglycon) at the enzymatic target site.
van Bemmel DM; Brank AS; Eritja R; Marquez VE; Christman JK
Biochem Pharmacol; 2009 Sep; 78(6):633-41. PubMed ID: 19467223
[TBL] [Abstract][Full Text] [Related]
9. S-adenosyl-L-methionine-dependent methyl transfer: observable precatalytic intermediates during DNA cytosine methylation.
Youngblood B; Shieh FK; Buller F; Bullock T; Reich NO
Biochemistry; 2007 Jul; 46(30):8766-75. PubMed ID: 17616174
[TBL] [Abstract][Full Text] [Related]
10. AdoMet-dependent methyl-transfer: Glu119 is essential for DNA C5-cytosine methyltransferase M.HhaI.
Shieh FK; Reich NO
J Mol Biol; 2007 Nov; 373(5):1157-68. PubMed ID: 17897676
[TBL] [Abstract][Full Text] [Related]
11. Functional roles of the conserved threonine 250 in the target recognition domain of HhaI DNA methyltransferase.
Vilkaitis G; Dong A; Weinhold E; Cheng X; Klimasauskas S
J Biol Chem; 2000 Dec; 275(49):38722-30. PubMed ID: 11102456
[TBL] [Abstract][Full Text] [Related]
12. Probing a rate-limiting step by mutational perturbation of AdoMet binding in the HhaI methyltransferase.
Merkiene E; Klimasauskas S
Nucleic Acids Res; 2005; 33(1):307-15. PubMed ID: 15653631
[TBL] [Abstract][Full Text] [Related]
13. Determination of the order of substrate addition to MspI DNA methyltransferase using a novel mechanism-based inhibitor.
Taylor C; Ford K; Connolly BA; Hornby DP
Biochem J; 1993 Apr; 291 ( Pt 2)(Pt 2):493-504. PubMed ID: 8484730
[TBL] [Abstract][Full Text] [Related]
14. Active site dynamics of the HhaI methyltransferase: insights from computer simulation.
Lau EY; Bruice TC
J Mol Biol; 1999 Oct; 293(1):9-18. PubMed ID: 10512711
[TBL] [Abstract][Full Text] [Related]
15. A structural basis for the preferential binding of hemimethylated DNA by HhaI DNA methyltransferase.
O'Gara M; Roberts RJ; Cheng X
J Mol Biol; 1996 Nov; 263(4):597-606. PubMed ID: 8918941
[TBL] [Abstract][Full Text] [Related]
16. Kinetic and catalytic mechanism of HhaI methyltransferase.
Wu JC; Santi DV
J Biol Chem; 1987 Apr; 262(10):4778-86. PubMed ID: 3558369
[TBL] [Abstract][Full Text] [Related]
17. Structure of the Q237W mutant of HhaI DNA methyltransferase: an insight into protein-protein interactions.
Dong A; Zhou L; Zhang X; Stickel S; Roberts RJ; Cheng X
Biol Chem; 2004 May; 385(5):373-9. PubMed ID: 15195996
[TBL] [Abstract][Full Text] [Related]
18. Protein-facilitated base flipping in DNA by cytosine-5-methyltransferase.
Huang N; Banavali NK; MacKerell AD
Proc Natl Acad Sci U S A; 2003 Jan; 100(1):68-73. PubMed ID: 12506195
[TBL] [Abstract][Full Text] [Related]
19. Nucleosides and nucleotides. CXIX. Inhibition of DNA-cytosine methylase HhaI by a self-complementary oligonucleotide containing 5-fluorocytosine.
Ono A; Matsuo Y; Matsuda A; Ueda T
Biol Pharm Bull; 1993 Jun; 16(6):529-33. PubMed ID: 8364503
[TBL] [Abstract][Full Text] [Related]
20. The role of Arg165 towards base flipping, base stabilization and catalysis in M.HhaI.
Shieh FK; Youngblood B; Reich NO
J Mol Biol; 2006 Sep; 362(3):516-27. PubMed ID: 16926025
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
