BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

295 related articles for article (PubMed ID: 12368474)

  • 41. Age-dependent neurofibrillary tangle formation, neuron loss, and memory impairment in a mouse model of human tauopathy (P301L).
    Ramsden M; Kotilinek L; Forster C; Paulson J; McGowan E; SantaCruz K; Guimaraes A; Yue M; Lewis J; Carlson G; Hutton M; Ashe KH
    J Neurosci; 2005 Nov; 25(46):10637-47. PubMed ID: 16291936
    [TBL] [Abstract][Full Text] [Related]  

  • 42. Spatial and temporal distribution of intracellular free cholesterol in brains of a Niemann-Pick type C mouse model showing hyperphosphorylated tau protein. Implications for Alzheimer's disease.
    Treiber-Held S; Distl R; Meske V; Albert F; Ohm TG
    J Pathol; 2003 May; 200(1):95-103. PubMed ID: 12692847
    [TBL] [Abstract][Full Text] [Related]  

  • 43. Accelerated amyloid deposition, neurofibrillary degeneration and neuronal loss in double mutant APP/tau transgenic mice.
    Ribé EM; Pérez M; Puig B; Gich I; Lim F; Cuadrado M; Sesma T; Catena S; Sánchez B; Nieto M; Gómez-Ramos P; Morán MA; Cabodevilla F; Samaranch L; Ortiz L; Pérez A; Ferrer I; Avila J; Gómez-Isla T
    Neurobiol Dis; 2005 Dec; 20(3):814-22. PubMed ID: 16125396
    [TBL] [Abstract][Full Text] [Related]  

  • 44. Characterization of a double (amyloid precursor protein-tau) transgenic: tau phosphorylation and aggregation.
    Pérez M; Ribe E; Rubio A; Lim F; Morán MA; Ramos PG; Ferrer I; Isla MT; Avila J
    Neuroscience; 2005; 130(2):339-47. PubMed ID: 15664690
    [TBL] [Abstract][Full Text] [Related]  

  • 45. Neurofibrillary degeneration in Alzheimer's disease: from molecular mechanisms to identification of drug targets.
    Pei JJ; Sjögren M; Winblad B
    Curr Opin Psychiatry; 2008 Nov; 21(6):555-61. PubMed ID: 18852562
    [TBL] [Abstract][Full Text] [Related]  

  • 46. The tau R406W mutation causes progressive presenile dementia with bitemporal atrophy.
    Ostojic J; Elfgren C; Passant U; Nilsson K; Gustafson L; Lannfelt L; Froelich Fabre S
    Dement Geriatr Cogn Disord; 2004; 17(4):298-301. PubMed ID: 15178940
    [TBL] [Abstract][Full Text] [Related]  

  • 47. Retarded axonal transport of R406W mutant tau in transgenic mice with a neurodegenerative tauopathy.
    Zhang B; Higuchi M; Yoshiyama Y; Ishihara T; Forman MS; Martinez D; Joyce S; Trojanowski JQ; Lee VM
    J Neurosci; 2004 May; 24(19):4657-67. PubMed ID: 15140937
    [TBL] [Abstract][Full Text] [Related]  

  • 48. SJLB mice develop tauopathy-induced parkinsonism.
    Takenokuchi M; Kadoyama K; Chiba S; Sumida M; Matsuyama S; Saigo K; Taniguchi T
    Neurosci Lett; 2010 Apr; 473(3):182-5. PubMed ID: 20178834
    [TBL] [Abstract][Full Text] [Related]  

  • 49. Val97Leu mutant presenilin-1 induces tau hyperphosphorylation and spatial memory deficit in mice and the underlying mechanisms.
    Wang Y; Cheng Z; Qin W; Jia J
    J Neurochem; 2012 Apr; 121(1):135-45. PubMed ID: 21929538
    [TBL] [Abstract][Full Text] [Related]  

  • 50. Transgenic expression of the shortest human tau affects its compartmentalization and its phosphorylation as in the pretangle stage of Alzheimer's disease.
    Brion JP; Tremp G; Octave JN
    Am J Pathol; 1999 Jan; 154(1):255-70. PubMed ID: 9916940
    [TBL] [Abstract][Full Text] [Related]  

  • 51. Pattern of tau hyperphosphorylation and neurotransmitter markers in the brainstem of senescent tau filament forming transgenic mice.
    Morcinek K; Köhler C; Götz J; Schröder H
    Brain Res; 2013 Feb; 1497():73-84. PubMed ID: 23261664
    [TBL] [Abstract][Full Text] [Related]  

  • 52. Vaccination with Sarkosyl insoluble PHF-tau decrease neurofibrillary tangles formation in aged tau transgenic mouse model: a pilot study.
    Ando K; Kabova A; Stygelbout V; Leroy K; Heraud C; Frédérick C; Suain V; Yilmaz Z; Authelet M; Dedecker R; Potier MC; Duyckaerts C; Brion JP
    J Alzheimers Dis; 2014; 40 Suppl 1():S135-45. PubMed ID: 24614899
    [TBL] [Abstract][Full Text] [Related]  

  • 53. Neurodegenerative disorder FTDP-17-related tau intron 10 +16C → T mutation increases tau exon 10 splicing and causes tauopathy in transgenic mice.
    Umeda T; Yamashita T; Kimura T; Ohnishi K; Takuma H; Ozeki T; Takashima A; Tomiyama T; Mori H
    Am J Pathol; 2013 Jul; 183(1):211-25. PubMed ID: 23680655
    [TBL] [Abstract][Full Text] [Related]  

  • 54. Elevated levels of soluble total and hyperphosphorylated tau result in early behavioral deficits and distinct changes in brain pathology in a new tau transgenic mouse model.
    Flunkert S; Hierzer M; Löffler T; Rabl R; Neddens J; Duller S; Schofield EL; Ward MA; Posch M; Jungwirth H; Windisch M; Hutter-Paier B
    Neurodegener Dis; 2013; 11(4):194-205. PubMed ID: 22797329
    [TBL] [Abstract][Full Text] [Related]  

  • 55. GFP-Mutant Human Tau Transgenic Mice Develop Tauopathy Following CNS Injections of Alzheimer's Brain-Derived Pathological Tau or Synthetic Mutant Human Tau Fibrils.
    Gibbons GS; Banks RA; Kim B; Xu H; Changolkar L; Leight SN; Riddle DM; Li C; Gathagan RJ; Brown HJ; Zhang B; Trojanowski JQ; Lee VM
    J Neurosci; 2017 Nov; 37(47):11485-11494. PubMed ID: 28986461
    [TBL] [Abstract][Full Text] [Related]  

  • 56. Increase in tau tyrosine phosphorylation correlates with the formation of tau aggregates.
    Vega IE; Cui L; Propst JA; Hutton ML; Lee G; Yen SH
    Brain Res Mol Brain Res; 2005 Aug; 138(2):135-44. PubMed ID: 15913839
    [TBL] [Abstract][Full Text] [Related]  

  • 57. Raphé tauopathy alters serotonin metabolism and breathing activity in terminal Tau.P301L mice: possible implications for tauopathies and Alzheimer's disease.
    Menuet C; Borghgraef P; Matarazzo V; Gielis L; Lajard AM; Voituron N; Gestreau C; Dutschmann M; Van Leuven F; Hilaire G
    Respir Physiol Neurobiol; 2011 Sep; 178(2):290-303. PubMed ID: 21763469
    [TBL] [Abstract][Full Text] [Related]  

  • 58. Tau assembly in inducible transfectants expressing wild-type or FTDP-17 tau.
    DeTure M; Ko LW; Easson C; Yen SH
    Am J Pathol; 2002 Nov; 161(5):1711-22. PubMed ID: 12414518
    [TBL] [Abstract][Full Text] [Related]  

  • 59. T-817MA, a neuroprotective agent, attenuates the motor and cognitive impairments associated with neuronal degeneration in P301L tau transgenic mice.
    Fukushima T; Nakamura A; Iwakami N; Nakada Y; Hattori H; Hoki S; Yamaguchi H; Nakagawa M; Terashima N; Narita H
    Biochem Biophys Res Commun; 2011 Apr; 407(4):730-4. PubMed ID: 21439944
    [TBL] [Abstract][Full Text] [Related]  

  • 60. Use of a phosphosensor dye in proteomic analysis of human mutant tau transgenic mice.
    Takano M; Otani M; Sakai A; Kadoyama K; Matsuyama S; Matsumoto A; Takenokuchi M; Sumida M; Taniguchi T
    Neuroreport; 2009 Dec; 20(18):1648-53. PubMed ID: 19898260
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 15.