121 related articles for article (PubMed ID: 12369867)
1. The microcystins and nodularins: cyclic polypeptide inhibitors of PP1 and PP2A.
Gulledgea BM; Aggena JB; Huangb HB; Nairnc AC; Chamberlin AR
Curr Med Chem; 2002 Nov; 9(22):1991-2003. PubMed ID: 12369867
[TBL] [Abstract][Full Text] [Related]
2. Microcystin analogues comprised only of Adda and a single additional amino acid retain moderate activity as PP1/PP2A inhibitors.
Gulledge BM; Aggen JB; Eng H; Sweimeh K; Chamberlin AR
Bioorg Med Chem Lett; 2003 Sep; 13(17):2907-11. PubMed ID: 14611855
[TBL] [Abstract][Full Text] [Related]
3. Linearized and truncated microcystin analogues as inhibitors of protein phosphatases 1 and 2A.
Gulledge BM; Aggen JB; Chamberlin AR
Bioorg Med Chem Lett; 2003 Sep; 13(17):2903-6. PubMed ID: 14611854
[TBL] [Abstract][Full Text] [Related]
4. Characterization of natural toxins with inhibitory activity against serine/threonine protein phosphatases.
Honkanen RE; Codispoti BA; Tse K; Boynton AL; Honkanan RE
Toxicon; 1994 Mar; 32(3):339-50. PubMed ID: 8016855
[TBL] [Abstract][Full Text] [Related]
5. The design, synthesis, and biological evaluation of analogues of the serine-threonine protein phosphatase 1 and 2A selective inhibitor microcystin LA: rational modifications imparting PP1 selectivity.
Aggen JB; Humphrey JM; Gauss CM; Huang HB; Nairn AC; Chamberlin AR
Bioorg Med Chem; 1999 Mar; 7(3):543-64. PubMed ID: 10220039
[TBL] [Abstract][Full Text] [Related]
6. Use of a colorimetric protein phosphatase inhibition assay and enzyme linked immunosorbent assay for the study of microcystins and nodularins.
An J; Carmichael WW
Toxicon; 1994 Dec; 32(12):1495-507. PubMed ID: 7725318
[TBL] [Abstract][Full Text] [Related]
7. A model for binding of structurally diverse natural product inhibitors of protein phosphatases PP1 and PP2A.
Gupta V; Ogawa AK; Du X; Houk KN; Armstrong RW
J Med Chem; 1997 Sep; 40(20):3199-206. PubMed ID: 9379439
[TBL] [Abstract][Full Text] [Related]
8. Cyanobacterial microcystin-LR is a potent and specific inhibitor of protein phosphatases 1 and 2A from both mammals and higher plants.
MacKintosh C; Beattie KA; Klumpp S; Cohen P; Codd GA
FEBS Lett; 1990 May; 264(2):187-92. PubMed ID: 2162782
[TBL] [Abstract][Full Text] [Related]
9. Inhibition of several protein phosphatases by a non-covalently interacting microcystin and a novel cyanobacterial peptide, nostocyclin.
Hastie CJ; Borthwick EB; Morrison LF; Codd GA; Cohen PT
Biochim Biophys Acta; 2005 Nov; 1726(2):187-93. PubMed ID: 16046071
[TBL] [Abstract][Full Text] [Related]
10. Microcystin-LR and okadaic acid-induced cellular effects: a dualistic response.
Gehringer MM
FEBS Lett; 2004 Jan; 557(1-3):1-8. PubMed ID: 14741332
[TBL] [Abstract][Full Text] [Related]
11. Using an enzyme linked immunosorbent assay (ELISA) and a protein phosphatase inhibition assay (PPIA) for the detection of microcystins and nodularins.
Carmichael WW; An J
Nat Toxins; 1999; 7(6):377-85. PubMed ID: 11122533
[TBL] [Abstract][Full Text] [Related]
12. In vivo and in vitro binding of microcystin to protein phosphatases 1 and 2A.
Runnegar M; Berndt N; Kong SM; Lee EY; Zhang L
Biochem Biophys Res Commun; 1995 Nov; 216(1):162-9. PubMed ID: 7488083
[TBL] [Abstract][Full Text] [Related]
13. Cantharimides: a new class of modified cantharidin analogues inhibiting protein phosphatases 1 and 2A.
McCluskey A; Walkom C; Bowyer MC; Ackland SP; Gardiner E; Sakoff JA
Bioorg Med Chem Lett; 2001 Nov; 11(22):2941-6. PubMed ID: 11677131
[TBL] [Abstract][Full Text] [Related]
14. Synthesis and biological evaluation of a targeted library of protein phosphatase inhibitors.
Wipf P; Aslan DC; Luci DK; Southwick EC; Lazo JS
Biotechnol Bioeng; 2000; 71(1):58-70. PubMed ID: 10629537
[TBL] [Abstract][Full Text] [Related]
15. Cyanobacterial PPP family protein phosphatases possess multifunctional capabilities and are resistant to microcystin-LR.
Shi L; Carmichael WW; Kennelly PJ
J Biol Chem; 1999 Apr; 274(15):10039-46. PubMed ID: 10187782
[TBL] [Abstract][Full Text] [Related]
16. Human and rat hepatocyte toxicity and protein phosphatase 1 and 2A inhibitory activity of naturally occurring desmethyl-microcystins and nodularins.
Ufelmann H; Krüger T; Luckas B; Schrenk D
Toxicology; 2012 Mar; 293(1-3):59-67. PubMed ID: 22230684
[TBL] [Abstract][Full Text] [Related]
17. A fluorescent microplate assay for microcystin-LR.
Fontal OI; Vieytes MR; Baptista de Sousa JM; Louzao MC; Botana LM
Anal Biochem; 1999 May; 269(2):289-96. PubMed ID: 10222000
[TBL] [Abstract][Full Text] [Related]
18. Serine-threonine protein phosphatase inhibitors: development of potential therapeutic strategies.
McCluskey A; Sim AT; Sakoff JA
J Med Chem; 2002 Mar; 45(6):1151-75. PubMed ID: 11881984
[No Abstract] [Full Text] [Related]
19. Protein phosphatases 1 and 2A promote Raf-1 activation by regulating 14-3-3 interactions.
Jaumot M; Hancock JF
Oncogene; 2001 Jul; 20(30):3949-58. PubMed ID: 11494123
[TBL] [Abstract][Full Text] [Related]
20. Role of phosphoprotein phosphatases in the corpus luteum: I identification and characterisation of serine/threonine phosphoprotein phosphatases in isolated rat luteal cells.
Ford SL; Abayasekara DR; Persaud SJ; Jones PM
J Endocrinol; 1996 Aug; 150(2):205-11. PubMed ID: 8869587
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]