BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

150 related articles for article (PubMed ID: 12369946)

  • 1. Purine nucleosides bearing 1-alkynyl chains as adenosine receptor agonists.
    Volpini R; Costanzi S; Lambertucci C; Vittori S; Cristalli G
    Curr Pharm Des; 2002; 8(26):2285-98. PubMed ID: 12369946
    [TBL] [Abstract][Full Text] [Related]  

  • 2. N(6)-alkyl-2-alkynyl derivatives of adenosine as potent and selective agonists at the human adenosine A(3) receptor and a starting point for searching A(2B) ligands.
    Volpini R; Costanzi S; Lambertucci C; Taffi S; Vittori S; Klotz KN; Cristalli G
    J Med Chem; 2002 Jul; 45(15):3271-9. PubMed ID: 12109910
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Medicinal chemistry and pharmacology of A2B adenosine receptors.
    Volpini R; Costanzi S; Vittori S; Cristalli G; Klotz KN
    Curr Top Med Chem; 2003; 3(4):427-43. PubMed ID: 12570760
    [TBL] [Abstract][Full Text] [Related]  

  • 4. 2-Alkynyl-8-aryl-9-methyladenines as novel adenosine receptor antagonists: their synthesis and structure-activity relationships toward hepatic glucose production induced via agonism of the A(2B) receptor.
    Harada H; Asano O; Hoshino Y; Yoshikawa S; Matsukura M; Kabasawa Y; Niijima J; Kotake Y; Watanabe N; Kawata T; Inoue T; Horizoe T; Yasuda N; Minami H; Nagata K; Murakami M; Nagaoka J; Kobayashi S; Tanaka I; Abe S
    J Med Chem; 2001 Jan; 44(2):170-9. PubMed ID: 11170626
    [TBL] [Abstract][Full Text] [Related]  

  • 5. 2-Alkynyl derivatives of adenosine-5'-N-ethyluronamide: selective A2 adenosine receptor agonists with potent inhibitory activity on platelet aggregation.
    Cristalli G; Volpini R; Vittori S; Camaioni E; Monopoli A; Conti A; Dionisotti S; Zocchi C; Ongini E
    J Med Chem; 1994 May; 37(11):1720-6. PubMed ID: 8201607
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Medicinal chemistry of adenosine A2A receptor agonists.
    Cristalli G; Lambertucci C; Taffi S; Vittori S; Volpini R
    Curr Top Med Chem; 2003; 3(4):387-401. PubMed ID: 12570757
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A2B adenosine receptor agonists: synthesis and biological evaluation of 2-phenylhydroxypropynyl adenosine and NECA derivatives.
    Vittori S; Costanzi S; Lambertucci C; Portino FR; Taffi S; Volpini R; Klotz KN; Cristalli G
    Nucleosides Nucleotides Nucleic Acids; 2004; 23(1-2):471-81. PubMed ID: 15043167
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Comparative pharmacology of human adenosine receptor subtypes - characterization of stably transfected receptors in CHO cells.
    Klotz KN; Hessling J; Hegler J; Owman C; Kull B; Fredholm BB; Lohse MJ
    Naunyn Schmiedebergs Arch Pharmacol; 1998 Jan; 357(1):1-9. PubMed ID: 9459566
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Adenosine receptor agonists: synthesis and biological evaluation of the diastereoisomers of 2-(3-hydroxy-3-phenyl-1-propyn-1-yl)NECA.
    Camaioni E; Di Francesco E; Vittori S; Volpini R; Cristalli G
    Bioorg Med Chem; 1997 Dec; 5(12):2267-75. PubMed ID: 9459024
    [TBL] [Abstract][Full Text] [Related]  

  • 10. 2-Alkynyl-8-aryladenines possessing an amide moiety: their synthesis and structure-activity relationships of effects on hepatic glucose production induced via agonism of the A(2B) adenosine receptor.
    Harada H; Asano O; Kawata T; Inoue T; Horizoe T; Yasuda N; Nagata K; Murakami M; Nagaoka J; Kobayashi S; Tanaka I; Abe S
    Bioorg Med Chem; 2001 Oct; 9(10):2709-26. PubMed ID: 11557358
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis and biological activity of new potential agonists for the human adenosine A2A receptor.
    Bosch MP; Campos F; Niubó I; Rosell G; Díaz JL; Brea J; Loza MI; Guerrero A
    J Med Chem; 2004 Jul; 47(16):4041-53. PubMed ID: 15267242
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Introduction of alkynyl chains on C-8 of adenosine led to very selective antagonists of the A(3) adenosine receptor.
    Volpini R; Costanzi S; Lambertucci C; Vittori S; Klotz K; Lorenzen A; Cristalli G
    Bioorg Med Chem Lett; 2001 Jul; 11(14):1931-4. PubMed ID: 11459663
    [TBL] [Abstract][Full Text] [Related]  

  • 13. 2-Substituted N-ethylcarboxamidoadenosine derivatives as high-affinity agonists at human A3 adenosine receptors.
    Klotz KN; Camaioni E; Volpini R; Kachler S; Vittori S; Cristalli G
    Naunyn Schmiedebergs Arch Pharmacol; 1999 Aug; 360(2):103-8. PubMed ID: 10494877
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis and biological activity of a new series of N6-arylcarbamoyl, 2-(Ar)alkynyl-N6-arylcarbamoyl, and N6-carboxamido derivatives of adenosine-5'-N-ethyluronamide as A1 and A3 adenosine receptor agonists.
    Baraldi PG; Cacciari B; Pineda de Las Infantas MJ; Romagnoli R; Spalluto G; Volpini R; Costanzi S; Vittori S; Cristalli G; Melman N; Park KS; Ji XD; Jacobson KA
    J Med Chem; 1998 Aug; 41(17):3174-85. PubMed ID: 9703463
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Design, synthesis, and biological evaluation of new 8-heterocyclic xanthine derivatives as highly potent and selective human A2B adenosine receptor antagonists.
    Baraldi PG; Tabrizi MA; Preti D; Bovero A; Romagnoli R; Fruttarolo F; Zaid NA; Moorman AR; Varani K; Gessi S; Merighi S; Borea PA
    J Med Chem; 2004 Mar; 47(6):1434-47. PubMed ID: 14998332
    [TBL] [Abstract][Full Text] [Related]  

  • 16. New substituted 9-alkylpurines as adenosine receptor ligands.
    Camaioni E; Costanzi S; Vittori S; Volpini R; Klotz KN; Cristalli G
    Bioorg Med Chem; 1998 May; 6(5):523-33. PubMed ID: 9629466
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Methanocarba analogues of purine nucleosides as potent and selective adenosine receptor agonists.
    Jacobson KA; Ji X; Li AH; Melman N; Siddiqui MA; Shin KJ; Marquez VE; Ravi RG
    J Med Chem; 2000 Jun; 43(11):2196-203. PubMed ID: 10841798
    [TBL] [Abstract][Full Text] [Related]  

  • 18. 2-Substituted adenosine derivatives: affinity and efficacy at four subtypes of human adenosine receptors.
    Gao ZG; Mamedova LK; Chen P; Jacobson KA
    Biochem Pharmacol; 2004 Nov; 68(10):1985-93. PubMed ID: 15476669
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Characterization of human A(2B) adenosine receptors: radioligand binding, western blotting, and coupling to G(q) in human embryonic kidney 293 cells and HMC-1 mast cells.
    Linden J; Thai T; Figler H; Jin X; Robeva AS
    Mol Pharmacol; 1999 Oct; 56(4):705-13. PubMed ID: 10496952
    [TBL] [Abstract][Full Text] [Related]  

  • 20. 2- and 8-alkynyl-9-ethyladenines: Synthesis and biological activity at human and rat adenosine receptors.
    Volpini R; Costanzi S; Lambertucci C; Vittori S; Martini C; Trincavelli ML; Klotz KN; Cristalli G
    Purinergic Signal; 2005 Jun; 1(2):173-81. PubMed ID: 18404502
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.