BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

132 related articles for article (PubMed ID: 12369980)

  • 1. Origin of chiral pharmacology: stereochemistry in metalloprotease inhibition.
    Kim DH
    Mini Rev Med Chem; 2001 Jul; 1(2):155-61. PubMed ID: 12369980
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mechanistic insight into the inactivation of carboxypeptidase A by alpha-benzyl-2-oxo-1,3-oxazolidine-4-acetic acid, a novel type of irreversible inhibitor for carboxypeptidase A with no stereospecificity.
    Chung SJ; Chung S; Lee HS; Kim EJ; Oh KS; Choi HS; Kim KS; Kim YJ; Hahn JH; Kim DH
    J Org Chem; 2001 Sep; 66(19):6462-71. PubMed ID: 11559199
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Syntheses and kinetic evaluation of racemic and optically active 2-benzyl-2-methyl-3,4-epoxybutanoic acids as irreversible inactivators for carboxypeptidase A.
    Lee M; Kim DH
    Bioorg Med Chem; 2002 Apr; 10(4):913-22. PubMed ID: 11836098
    [TBL] [Abstract][Full Text] [Related]  

  • 4. N-(Hydroxyaminocarbonyl)phenylalanine: a novel class of inhibitor for carboxypeptidase A.
    Chung SJ; Kim DH
    Bioorg Med Chem; 2001 Jan; 9(1):185-9. PubMed ID: 11197339
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Insight into the stereochemistry in the inhibition of carboxypeptidase A with N-(hydroxyaminocarbonyl)phenylalanine: binding modes of an enantiomeric pair of the inhibitor to carboxypeptidase A.
    Cho JH; Kim DH; Chung SJ; Ha NC; Oh BH; Yong Choi K
    Bioorg Med Chem; 2002 Jun; 10(6):2015-22. PubMed ID: 11937361
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Principles of hydroxamate inhibition of metalloproteases: carboxypeptidase A.
    Mock WL; Cheng H
    Biochemistry; 2000 Nov; 39(45):13945-52. PubMed ID: 11076537
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Sulfamide-based inhibitors for carboxypeptidase A. Novel type transition state analogue inhibitors for zinc proteases.
    Park JD; Kim DH; Kim SJ; Woo JR; Ryu SE
    J Med Chem; 2002 Nov; 45(24):5295-302. PubMed ID: 12431056
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A novel strategy for designing irreversible inhibitors of metalloproteases: acetals as latent electrophiles that interact with catalytic nucleophile at the active site.
    Han MS; Ryu CH; Chung SJ; Kim DH
    Org Lett; 2000 Oct; 2(20):3149-52. PubMed ID: 11009368
    [TBL] [Abstract][Full Text] [Related]  

  • 9. 2-Benzyl-3,4-iminobutanoic acid as inhibitor of carboxypeptidase A.
    Park JI; Kim DH
    Bioorg Med Chem Lett; 2001 Nov; 11(22):2967-70. PubMed ID: 11677137
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Irreversible inhibition of zinc-containing protease by oxazolidinone derivatives. Novel inactivation chemistry.
    Kim DH; Chung SJ; Kim EJ; Tian GR
    Bioorg Med Chem Lett; 1998 Apr; 8(7):859-64. PubMed ID: 9871555
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Design of mechanism-based carboxypeptidase A inactivators on the basis of the X-ray crystal structure and catalytic reaction pathway.
    Lee KJ; Kim DH
    Bioorg Med Chem; 1998 Sep; 6(9):1613-22. PubMed ID: 9801832
    [TBL] [Abstract][Full Text] [Related]  

  • 12. First hydroxamate inhibitors for carboxypeptidase A. N-acyl-N-hydroxy-beta-phenylalanines.
    Kim DH; Jin Y
    Bioorg Med Chem Lett; 1999 Mar; 9(5):691-6. PubMed ID: 10201830
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Nitro as a novel zinc-binding group in the inhibition of carboxypeptidase A.
    Wang SH; Wang SF; Xuan W; Zeng ZH; Jin JY; Ma J; Tian GR
    Bioorg Med Chem; 2008 Apr; 16(7):3596-601. PubMed ID: 18289863
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Cysteine derivatives as inhibitors for carboxypeptidase A: synthesis and structure-activity relationships.
    Park JD; Kim DH
    J Med Chem; 2002 Feb; 45(4):911-8. PubMed ID: 11831903
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Effect of zinc ion on the inhibition of carboxypeptidase A by imidazole-bearing substrate analogues.
    Han MS; Kim DH
    Bioorg Med Chem Lett; 2001 Jun; 11(11):1425-7. PubMed ID: 11378369
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Crystal structure of carboxypeptidase A complexed with D-cysteine at 1.75 A - inhibitor-induced conformational changes.
    van Aalten DM; Chong CR; Joshua-Tor L
    Biochemistry; 2000 Aug; 39(33):10082-9. PubMed ID: 10955996
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structure-based design and synthesis of novel non-zinc chelating MMP-12 inhibitors.
    Dublanchet AC; Ducrot P; Andrianjara C; O'Gara M; Morales R; Compère D; Denis A; Blais S; Cluzeau P; Courté K; Hamon J; Moreau F; Prunet ML; Tertre A
    Bioorg Med Chem Lett; 2005 Aug; 15(16):3787-90. PubMed ID: 16002291
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A new inhibitor design strategy for carboxypeptidase A as exemplified by N-(2-chloroethyl)-N-methylphenylalanine.
    Park JD; Lee KJ; Kim DH
    Bioorg Med Chem; 2001 Feb; 9(2):237-43. PubMed ID: 11249116
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Stereoselective inhibition of glutamate carboxypeptidase by chiral phosphonothioic acids.
    Lu H; Berkman CE
    Bioorg Med Chem; 2001 Feb; 9(2):395-402. PubMed ID: 11249132
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A new type of carboxypeptidase A inhibitors designed using an imidazole as a zinc coordinating ligand.
    Lee KJ; Joo KC; Kim EJ; Lee M; Kim DH
    Bioorg Med Chem; 1997 Oct; 5(10):1989-98. PubMed ID: 9370042
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.