These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

120 related articles for article (PubMed ID: 12372530)

  • 1. Substituted uracil derivatives as potent inhibitors of poly(ADP-ribose)polymerase-1 (PARP-1).
    Steinhagen H; Gerisch M; Mittendorf J; Schlemmer KH; Albrecht B
    Bioorg Med Chem Lett; 2002 Nov; 12(21):3187-90. PubMed ID: 12372530
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Novel poly(ADP-ribose) polymerase-1 inhibitors.
    Dunn D; Husten J; Ator MA; Chatterjee S
    Bioorg Med Chem Lett; 2007 Jan; 17(2):542-5. PubMed ID: 17074482
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Phthalazinones 2: Optimisation and synthesis of novel potent inhibitors of poly(ADP-ribose)polymerase.
    Cockcroft XL; Dillon KJ; Dixon L; Drzewiecki J; Kerrigan F; Loh VM; Martin NM; Menear KA; Smith GC
    Bioorg Med Chem Lett; 2006 Feb; 16(4):1040-4. PubMed ID: 16290932
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Design and synthesis of poly(ADP-ribose)polymerase-1 (PARP-1) inhibitors. Part 3: In vitro evaluation of 1,3,4,5-tetrahydro-benzo[c][1,6]- and [c][1,7]-naphthyridin-6-ones.
    Ferraris D; Ficco RP; Pahutski T; Lautar S; Huang S; Zhang J; Kalish V
    Bioorg Med Chem Lett; 2003 Aug; 13(15):2513-8. PubMed ID: 12852955
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis and biological evaluation of substituted 2-phenyl-2H-indazole-7-carboxamides as potent poly(ADP-ribose) polymerase (PARP) inhibitors.
    Scarpelli R; Boueres JK; Cerretani M; Ferrigno F; Ontoria JM; Rowley M; Schultz-Fademrecht C; Toniatti C; Jones P
    Bioorg Med Chem Lett; 2010 Jan; 20(2):488-92. PubMed ID: 20007017
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis and evaluation of tricyclic derivatives containing a non-aromatic amide as inhibitors of poly(ADP-ribose)polymerase-1 (PARP-1).
    Park CH; Chun K; Joe BY; Park JS; Kim YC; Choi JS; Ryu DK; Koh SH; Cho GW; Kim SH; Kim MH
    Bioorg Med Chem Lett; 2010 Apr; 20(7):2250-3. PubMed ID: 20189385
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Design and synthesis of novel 5,6-disubstituted uracil derivatives as potent inhibitors of thymidine phosphorylase.
    Nencka R; Votruba I; Hrebabecký H; Tloust'ová E; Horská K; Masojídková M; Holý A
    Bioorg Med Chem Lett; 2006 Mar; 16(5):1335-7. PubMed ID: 16337119
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Phthalazinones. Part 1: The design and synthesis of a novel series of potent inhibitors of poly(ADP-ribose)polymerase.
    Loh VM; Cockcroft XL; Dillon KJ; Dixon L; Drzewiecki J; Eversley PJ; Gomez S; Hoare J; Kerrigan F; Matthews IT; Menear KA; Martin NM; Newton RF; Paul J; Smith GC; Vile J; Whittle AJ
    Bioorg Med Chem Lett; 2005 May; 15(9):2235-8. PubMed ID: 15837300
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Design, synthesis, and evaluation in vitro of quinoline-8-carboxamides, a new class of poly(adenosine-diphosphate-ribose)polymerase-1 (PARP-1) inhibitor.
    Lord AM; Mahon MF; Lloyd MD; Threadgill MD
    J Med Chem; 2009 Feb; 52(3):868-77. PubMed ID: 19117416
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A novel and potent poly(ADP-ribose) polymerase-1 inhibitor, FR247304 (5-chloro-2-[3-(4-phenyl-3,6-dihydro-1(2H)-pyridinyl)propyl]-4(3H)-quinazolinone), attenuates neuronal damage in in vitro and in vivo models of cerebral ischemia.
    Iwashita A; Tojo N; Matsuura S; Yamazaki S; Kamijo K; Ishida J; Yamamoto H; Hattori K; Matsuoka N; Mutoh S
    J Pharmacol Exp Ther; 2004 Aug; 310(2):425-36. PubMed ID: 15075382
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis and enzymatic evaluation of pyridinium-substituted uracil derivatives as novel inhibitors of thymidine phosphorylase.
    Murray PE; McNally VA; Lockyer SD; Williams KJ; Stratford IJ; Jaffar M; Freeman S
    Bioorg Med Chem; 2002 Mar; 10(3):525-30. PubMed ID: 11814838
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Novel alkoxybenzamide inhibitors of poly(ADP-ribose) polymerase.
    Menear KA; Adcock C; Alonso FC; Blackburn K; Copsey L; Drzewiecki J; Fundo A; Le Gall A; Gomez S; Javaid H; Lence CF; Martin NM; Mydlowski C; Smith GC
    Bioorg Med Chem Lett; 2008 Jul; 18(14):3942-5. PubMed ID: 18579376
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Identification of substituted pyrazolo[1,5-a]quinazolin-5(4H)-one as potent poly(ADP-ribose)polymerase-1 (PARP-1) inhibitors.
    Orvieto F; Branca D; Giomini C; Jones P; Koch U; Ontoria JM; Palumbi MC; Rowley M; Toniatti C; Muraglia E
    Bioorg Med Chem Lett; 2009 Aug; 19(15):4196-200. PubMed ID: 19541484
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Improved synthesis of antibacterial 3-substituted 6-anilinouracils.
    Svenstrup N; Kuhl A; Ehlert K; Häbich D
    Bioorg Med Chem Lett; 2008 Jun; 18(11):3215-8. PubMed ID: 18468893
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Design and synthesis of poly(ADP-ribose) polymerase-1 (PARP-1) inhibitors. Part 4: biological evaluation of imidazobenzodiazepines as potent PARP-1 inhibitors for treatment of ischemic injuries.
    Ferraris D; Ficco RP; Dain D; Ginski M; Lautar S; Lee-Wisdom K; Liang S; Lin Q; Lu MX; Morgan L; Thomas B; Williams LR; Zhang J; Zhou Y; Kalish VJ
    Bioorg Med Chem; 2003 Aug; 11(17):3695-707. PubMed ID: 12901915
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis of 3-substituted benzamides and 5-substituted isoquinolin-1(2H)-ones and preliminary evaluation as inhibitors of poly(ADP-ribose)polymerase (PARP).
    Watson CY; Whish WJ; Threadgill MD
    Bioorg Med Chem; 1998 Jun; 6(6):721-34. PubMed ID: 9681138
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Inhibition of uridine phosphorylase: synthesis and structure-activity relationships of aryl-substituted 5-benzyluracils and 1-[(2-hydroxyethoxy)methyl]-5-benzyluracils.
    Orr GF; Musso DL; Boswell GE; Kelley JL; Joyner SS; Davis ST; Baccanari DP
    J Med Chem; 1995 Sep; 38(19):3850-6. PubMed ID: 7562916
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Design, synthesis, and cytoprotective effect of 2-aminothiazole analogues as potent poly(ADP-ribose) polymerase-1 inhibitors.
    Zhang WT; Ruan JL; Wu PF; Jiang FC; Zhang LN; Fang W; Chen XL; Wang Y; Cao BS; Chen GY; Zhu YJ; Gu J; Chen JG
    J Med Chem; 2009 Feb; 52(3):718-25. PubMed ID: 19125579
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Minocycline inhibits poly(ADP-ribose) polymerase-1 at nanomolar concentrations.
    Alano CC; Kauppinen TM; Valls AV; Swanson RA
    Proc Natl Acad Sci U S A; 2006 Jun; 103(25):9685-90. PubMed ID: 16769901
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Rational design of conformationally restricted quinazolinone inhibitors of poly(ADP-ribose)polymerase.
    Hattori K; Kido Y; Yamamoto H; Ishida J; Iwashita A; Mihara K
    Bioorg Med Chem Lett; 2007 Oct; 17(20):5577-81. PubMed ID: 17804225
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.