These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

162 related articles for article (PubMed ID: 12373540)

  • 1. Antidepressant-like effect of MPEP, a potent, selective and systemically active mGlu5 receptor antagonist in the olfactory bulbectomized rats.
    Wieronska JM; Szewczyk B; Branski P; Palucha A; Pilc A
    Amino Acids; 2002; 23(1-3):213-6. PubMed ID: 12373540
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Potential antidepressant-like effect of MTEP, a potent and highly selective mGluR5 antagonist.
    Pałucha A; Brański P; Szewczyk B; Wierońska JM; Kłak K; Pilc A
    Pharmacol Biochem Behav; 2005 Aug; 81(4):901-6. PubMed ID: 16040106
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Potential anxiolytic- and antidepressant-like effects of MPEP, a potent, selective and systemically active mGlu5 receptor antagonist.
    Tatarczyńska E; Klodzińska A; Chojnacka-Wójcik E; Palucha A; Gasparini F; Kuhn R; Pilc A
    Br J Pharmacol; 2001 Apr; 132(7):1423-30. PubMed ID: 11264235
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Anxiolytic-like effects of group I metabotropic glutamate antagonist 2-methyl-6-(phenylethynyl)-pyridine (MPEP) in rats.
    Kłodzińska A; Tatarczyńska E; Chojnacka-Wójcik E; Pilc A
    Pol J Pharmacol; 2000; 52(6):463-6. PubMed ID: 11334240
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Metabotropic glutamate 5 receptor antagonism is associated with antidepressant-like effects in mice.
    Li X; Need AB; Baez M; Witkin JM
    J Pharmacol Exp Ther; 2006 Oct; 319(1):254-9. PubMed ID: 16803860
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Multiple MPEP administrations evoke anxiolytic- and antidepressant-like effects in rats.
    Pilc A; Kłodzińska A; Brański P; Nowak G; Pałucha A; Szewczyk B; Tatarczyńska E; Chojnacka-Wójcik E; Wierońska JM
    Neuropharmacology; 2002 Aug; 43(2):181-7. PubMed ID: 12213272
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mutational analysis and molecular modeling of the binding pocket of the metabotropic glutamate 5 receptor negative modulator 2-methyl-6-(phenylethynyl)-pyridine.
    Malherbe P; Kratochwil N; Zenner MT; Piussi J; Diener C; Kratzeisen C; Fischer C; Porter RH
    Mol Pharmacol; 2003 Oct; 64(4):823-32. PubMed ID: 14500738
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Interactive effects of the mGlu5 receptor antagonist MPEP and the mGlu2/3 receptor antagonist LY341495 on nicotine self-administration and reward deficits associated with nicotine withdrawal in rats.
    Liechti ME; Markou A
    Eur J Pharmacol; 2007 Jan; 554(2-3):164-74. PubMed ID: 17113075
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Antagonism at metabotropic glutamate 5 receptors inhibits nicotine- and cocaine-taking behaviours and prevents nicotine-triggered relapse to nicotine-seeking.
    Tessari M; Pilla M; Andreoli M; Hutcheson DM; Heidbreder CA
    Eur J Pharmacol; 2004 Sep; 499(1-2):121-33. PubMed ID: 15363959
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The mGlu5 receptor antagonist MPEP activates specific stress-related brain regions and lacks neurotoxic effects of the NMDA receptor antagonist MK-801: significance for the use as anxiolytic/antidepressant drug.
    Inta D; Filipovic D; Lima-Ojeda JM; Dormann C; Pfeiffer N; Gasparini F; Gass P
    Neuropharmacology; 2012 Apr; 62(5-6):2034-9. PubMed ID: 22261382
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The effect of the mGlu5 receptor antagonist MPEP in rodent tests of anxiety and cognition: a comparison.
    Ballard TM; Woolley ML; Prinssen E; Huwyler J; Porter R; Spooren W
    Psychopharmacology (Berl); 2005 Apr; 179(1):218-29. PubMed ID: 15739074
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Anxiolytic-like effects of the prototypical metabotropic glutamate receptor 5 antagonist 2-methyl-6-(phenylethynyl)pyridine in rodents.
    Spooren WP; Vassout A; Neijt HC; Kuhn R; Gasparini F; Roux S; Porsolt RD; Gentsch C
    J Pharmacol Exp Ther; 2000 Dec; 295(3):1267-75. PubMed ID: 11082464
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Antidepressant-like effects of mGluR1 and mGluR5 antagonists in the rat forced swim and the mouse tail suspension tests.
    Belozertseva IV; Kos T; Popik P; Danysz W; Bespalov AY
    Eur Neuropsychopharmacol; 2007 Feb; 17(3):172-9. PubMed ID: 16630709
    [TBL] [Abstract][Full Text] [Related]  

  • 14. [3H]Methoxymethyl-3-[(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridine binding to metabotropic glutamate receptor subtype 5 in rodent brain: in vitro and in vivo characterization.
    Anderson JJ; Rao SP; Rowe B; Giracello DR; Holtz G; Chapman DF; Tehrani L; Bradbury MJ; Cosford ND; Varney MA
    J Pharmacol Exp Ther; 2002 Dec; 303(3):1044-51. PubMed ID: 12438526
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Neuroprotective effect caused by MPEP, an antagonist of metabotropic glutamate receptor mGluR5, on seizures induced by pilocarpine in 21-day-old rats.
    Jesse CR; Savegnago L; Rocha JB; Nogueira CW
    Brain Res; 2008 Mar; 1198():197-203. PubMed ID: 18242586
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Evidence that the metabotropic glutamate receptor 5 antagonist MPEP may act as an inhibitor of the norepinephrine transporter in vitro and in vivo.
    Heidbreder CA; Bianchi M; Lacroix LP; Faedo S; Perdona E; Remelli R; Cavanni P; Crespi F
    Synapse; 2003 Dec; 50(4):269-76. PubMed ID: 14556231
    [TBL] [Abstract][Full Text] [Related]  

  • 17. 2-Methyl-6-(phenylethynyl)-pyridine (MPEP), a potent, selective and systemically active mGlu5 receptor antagonist.
    Gasparini F; Lingenhöhl K; Stoehr N; Flor PJ; Heinrich M; Vranesic I; Biollaz M; Allgeier H; Heckendorn R; Urwyler S; Varney MA; Johnson EC; Hess SD; Rao SP; Sacaan AI; Santori EM; Veliçelebi G; Kuhn R
    Neuropharmacology; 1999 Oct; 38(10):1493-503. PubMed ID: 10530811
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Prolonged administration of antidepressant drugs leads to increased binding of [(3)H]MPEP to mGlu5 receptors.
    Nowak G; Pomierny-Chamioło L; Siwek A; Niedzielska E; Pomierny B; Pałucha-Poniewiera A; Pilc A
    Neuropharmacology; 2014 Sep; 84():46-51. PubMed ID: 24796254
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Effects of MPEP, a selective metabotropic glutamate mGlu5 ligand, on sleep and wakefulness in the rat.
    Cavas M; Scesa G; Navarro JF
    Prog Neuropsychopharmacol Biol Psychiatry; 2013 Jan; 40():18-25. PubMed ID: 23022670
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Anticonvulsant activity of two metabotropic glutamate group I antagonists selective for the mGlu5 receptor: 2-methyl-6-(phenylethynyl)-pyridine (MPEP), and (E)-6-methyl-2-styryl-pyridine (SIB 1893).
    Chapman AG; Nanan K; Williams M; Meldrum BS
    Neuropharmacology; 2000 Jul; 39(9):1567-74. PubMed ID: 10854901
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.